This issue of Neurosurgery Clinics focuses on Controversies in Spinal and Cranial Surgery. Article topics will include:Sacro-illiac Fusion; Interspinous Spacers;Bone Morphogenetic Protein, Platelet Concentrates and Other Biologics; MIS decompression; Pipeline flow diversion in subarachnoid hemorrhage; Direct versus indirect bypass for moyamoya disease; Management of prenatally diagnosed myelomeningocele; Management of incidental aneurysm; Surgical management of incidental low-grade glioma; and more!

This issue will focus on both adult and pediatric spine trauma. Featured articles are as follows: Pharmacologic Treatment of SCI; Classification of Adult Subaxial Cervical Trauma; Classification and Management of Pediatric Craniocervical Injuries; Classification and Management of Pediatric Subaxial Injuries; Classification of Adult Thoracolumbar Injuries; Management of Pediatric Thoracolumber Injuries; Treatment of Odontoid Fractures in the Aging Population; Treatment of Facet Fractures in the Cervical Spine; and many more!

This issue of Neurosurgery Clinics offers a broad review of current topics surrounding trigeminal neuralgia including: Overview and History, Diagnosis/Etiology, Scales of measuring TN pain and response, Medical Therapy, Role of Imaging, Rhizotomy, SRS, Microscopic MVD, Neuromodulation, and many more articles that focus on trigeminal neuralgia.

This issue focuses on meningiomas and includes articles on Incidental Meningiomas: Management Strategies in the Modern Neuroimaging Era, Advanced Neuroimaging for Intracranial Meningiomas, Endoscopic Endonasal and Keyhole Surgery for the Management of Skull Base Meningiomas, Preoperative Embolization for Intracranial Meningiomas, Management of Spinal Meningiomas, Medical Management of Meningiomas: Current Status, Failed Treatments and Promising Horizons, and many more!

In this book, the biology, current treatment modalities and new emerging therapeutic approaches and targets for glioma, a highly aggressive and invasive brain tumour, are described. The pathologic features of the most frequently WHO classified gliomas encountered in clinical practice, are reviewed. Molecular genetics and specifically the mutations that underlie brain tumours are outlined as is the inherited genetic susceptibility and lifestyle risk factors reflecting on glioma epidemiology. The clinical features of glioma as well as diagnostic methods that include conventional and advanced magnetic resonance imaging (MRI) and brain mapping are also discussed with an outline of emerging treatment options.

This book presents current research in the study of the causes, management and prognosis in brain damage including the implications for therapeutic intervention in the reorganisation of elementary functions (REF) after brain injury; a reorientation towards fibre tracts damage in amnesia; the use of alkaline comet assay to assess DNA damage and repair in brain damage; responsiveness and prognosis in the severe disorder of consciousness; the pathophysiology, management and prognosis of cerebral radiation necrosis; exercise as a therapeutic approach after brain damage; neuroprotection in experimental cerebral ischemia; and initiation of inflammatory mechanisms in acute brain damage.

Surgical Neuroangiography: Clinical and Interventional Aspects in Adults covers a variety of protocols and strategies combining functional vascular anatomy with a complete appreciation of the various disease processes, their pathophysiology, clinical presentation, and natural history, as well as recent technological advances. The newer endovascular techniques that apply to embolization of aneurysms, vascular malformations, and tumors of the spine, spinal cord, brain, and maxillofacial areas are reviewed. Novel techniques of revascularization for occlusive vascular diseases in the brachiocephalic and cerebral vasculature are expanding and revolutionizing the field. Implementing optimally efficient and safe strategies for occlusion or revascularization of arterial or venous structures requires the knowledge of collateral circulation covered in this volume. Alejandro Berenstein, Pierre Lasjaunias, and Karel ter Brugge, pioneers in the field with over 20 years of experience, present the second volume of the second edition of Surgical Neuroangiography, combining volumes 2, 4 and 5 of the previous edition and adding a new section, "Occlusive Vascular Diseases." Comprehensive, practice-oriented work on vascular intervention in adults and children Written by the leading experts with many years' experience in research and teaching Richly illustrated overview of all treatment modalities

In neurotechnology, deep brain stimulation (DBS) refers to a surgical treatment involving the implantation of a medical device called a brain pacemaker, which sends electrical impulses to specific parts of the brain. DBS in select brain regions has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders such as chronic pain, Parkinson's disease, tremor and dystonia. Despite the long history of DBS, its underlying principles and mechanisms are still not clear. While DBS has proven helpful for some patients, there is potential for serious complications and side effects. This book presents current research on this cutting edge treatment. Success of functional stereotactic procedures is shown to depend on a variety of factors, including patient selection, methodology of choice and localisation of the target, and the experience of the neurosurgery team. Complications on the use of the procedure in the treatment of Parkinson's Disease are also presented. The use of Vagus nerve stimulation on treatment-resistant patients with major depression is discussed as well.

Authoritative and lavishly illustrated, this best-selling reference returns in a fourth edition with comprehensive coverage of the current imaging strategies for the evaluation of disease processes affecting the temporal bone and its intricate anatomy. New in this edition is a highly practical "how-to" chapter that presents imaging modalities and technical parameters for CT and MRI as well as an overview of the role of plain film radiography, ultrasound, PET, and PET/CT. The chapter then addresses major clinical indications, providing step-by-step descriptions of how to protocol each case, how to interpret the studies, and how to report findings. The remaining chapters thoroughly cover specific anatomic areas of the temporal bone separately. Each chapter places special emphasis on gaining a solid foundation of the normal anatomy and anatomic variations. It then discusses imaging protocols and image evaluation for specific clinical problems. Highlights: Practical discussion of standard techniques, protocols, and special considerations for imaging using CT and MRI In-depth coverage of both common and rare conditions Clinical insights from international authorities in the field More than 1,500 high-quality illustrations and images, including CT, MRI, and vascular images using CTA, MRA, and conventional catheter angiography This book is an essential reference for a multidisciplinary approach to assessing diseases affecting the temporal bone. It is an ideal resource for all radiologists, neuroradiologists, head and neck radiologists, and residents in these specialties. It is also valuable for otolaryngologists, otologists, and head and neck surgeons.

"An extraordinary story that you will pick up and finish in a few hours of remarkable reading. The account of her son's and her family's regeneration is simply inspiring. It will be instructive to any family with a child with a disabling condition. But as the account of a transfiguring experience and the sensitive interpretation of how it came about, it speaks to all of us."--Arthur Kleinman, Harvard Medical School, author of "Writing at the Margin"

"Ruthann Johansen's loving account of the aftermath of her son's traumatic brain injury is an extraordinary book, . . . at once a profound meditation about the inextricable relationship between language, story-telling, and self-formation and a moving account of how one young man reconstructed his life in dialogue with the solicitations and offerings of family, friends, and caring others. This book should be read by everyone who is interested in the nature of identity and selfhood."--Janice A. Radway, Duke University, author of "A Feeling for Books: The Book-Of-The-Month Club, Literary Taste, and Middle-Class Desire

"This book clearly asks the question: Who speaks for the traumatically brain injured? It should be required reading for all neuroscientists who are providers of care or who are diligently conducting research to find a therapy that truly produces recovery of function."--David A. Hovda, Professor of Neurosurgery and Director of the Brain Injury Research Center, University of California, Los Angeles

"A singular contribution to our understanding of brain injury as illness experience, of the family dynamics of care, and of the narrative nature of lives and brains. The writing is lyrical, moving, and scholarly, not by turns butat the same time. Johansen conveys mother love, feminist self-awareness, and a critical social perspective to provide a unique account of family life through continuing trauma."--Arthur W. Frank, author of "The Wounded Storyteller: Body, Illness, and Ethics

"This book is gripping and inspired. . . . It will be of great solace and usefulness to others who find themselves in such circumstances, part of the literature of family disaster. It will find an audience as well among all those concerned with what might be called the construction of the self, which would include a good many in various psychological fields."--F. Robert Rodman, author of "Not Dying: A Memoir

This book is the result of the authors' many years of experience in using neurosurgical lasers. They began using laser diodes in their speciality at the start of the 1990s, making them pioneers in the field. The first part of the book deals with the general physical bases and comparative bio-tissue effects of the various kinds of surgical laser, safety measures required and legislation concerning powerful lasers. The second part focuses on laser diodes alone. The authors describe in detail how they use them to operate on intracranial and intraspinal tumours, in intraventricular endoscopy, and in surgery involving epilepsy. Details are given of: technical data; the choice of parameters depending on how the lasers are used (contact and non-contact, and the type of lesion being operated on) as well as their indications in neurosurgery. The authors emphasise the practical recommendations that make this book a valuable companion for current and potential users working in neurosurgery and other surgical applications. They also mention the new and future uses of laser diodes which are currently being developed and which show that this equipment really does represent a new generation of lasers. About 100 colour illustrations and tables are used to explain and underscore the authors' points.

In this issue of Neurosurgery Clinics, guest editors Drs. Peter Nakaji and Oliver Bozinov bring their considerable expertise to the topic of Ablative Therapies in Neurosurgery. Top experts in the field cover key topics such as MR-guided laser interstitial thermal therapy for infield of brain metastases; awake LITT; high frequency ultrasound ablation in neurosurgery; current application of ablative therapies for trigeminal neuralgia; and more. Contains 12 relevant, practice-oriented topics including laser interstitial thermal therapy for radionecrosis; posterior fossa LITT in children; neurosurgical applications of magnetic hyperthermia therapy (MHT); laser interstitial thermal therapy for epilepsy; pros and cons of ablation for functional neurosurgery in the neurostimulation age; and more.  Provides in-depth clinical reviews on ablative therapies in neurosurgery, offering actionable insights for clinical practice.  Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews. 

In this issue of Neurosurgery Clinics, guest editors Drs. David D. Limbrick and Jeffrey Leonard bring their considerable expertise to Chiari I Malformation. Top experts in the field cover key topics such as comorbidities associated with Chiari I malformation; orthostatic intolerance and Chiari I malformation; clinical manifestations of Chiari I malformation; imaging in Chiari I malformation; posterior fossa decompression for Chiari I malformation; and more. Contains 21 relevant, practice-oriented topics sociodemographics of Chiari I malformation; Chiari I malformation and sleep disordered breathing; complex Chiari: diagnosis, evaluation, and treatment; new insights into craniovertebral junction instability in Chiari I malformation; spine deformity associated with Chiari I malformation and syringomyelia; and more. Provides in-depth clinical reviews on Chiari I malformation, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This book has included 19 recent topics about the treatment of cerebrovascular diseases from basics to surgical (include microneurosurgical, endovascular, endoscopic and Stereotactic radiosurgical techniques) aspects in the management of cerebrovascular diseases. With illustrative cases, the treatment strategies, techniques and complication avoidance have been covered extensively in the chapters to guide the readers on when and what to expect the worst in surgeries. The neurosurgical aspect in the present scenario of COVID is also included. This book will assist the junior neurosurgeons and junior neurological physicians in endeavoring to learn the core concepts and common problems of cerebrovascular surgery. This is a worthwhile addition in this ever growing field of cerebrovascular surgery.

Filling a gap in the literature, this is the first book to comprehensively discuss 3D printing applied to bone surgery. It provides both the scientific basics and practical applications, with a special focus on 3D-printed, custom-made titanium prostheses (3DPCMP) used for bone reconstruction following tumor resection. Initially applied to pelvic and scapular prostheses - because of their of highly complex anatomy - this technology is increasingly being adopted in other fields of orthopedics, such as limb surgery, traumatology and degenerative diseases. Throughout the book, experts from various fields share their knowledge, describing 3D printing applied to the reconstruction of different bone segments, reviewing each application and comparing it with traditional reconstruction. They also present real-world case studies from their clinical practice. Uniquely responding to the growing interest surrounding 3D printing for bone reconstruction, this book is invaluable for orthopedic, neuro- , head and neck as well as maxillofacial surgeons wishing to gain insights into this new and promising field.

This Atlas summarizes current surgical strategy for cerebral revascularization in the treatment of complex neurovascular diseases. It focuses on complex intracranial aneurysms, which are mostly large/giant, irregular and short of enough collateral compensation. In the first part, it starts from the extracranial-intracranial (EC-IC) bypass strategy. For the complex middle cerebral artery aneurysms, the types of EC-IC bypass are determined based on the angioarchitecture. Furthermore, various intracranial-intracranial (IC-IC) bypasses are introduced, with the advantage of no need for graft vessel harvesting and preferable matching of donor and receipt arteries. This Atlas provides useful knowledge and cases about this basic and indispensable skill for neurosurgeons.

The quintessential reference for bedside medical management of neurocritical care patients Medical management of patients in the neurocritical care unit (NCCU) often spells the difference between life or death and return to normal function or a lifetime disability. As such, it is vital that patients with life-threatening neurological and neurosurgical illnesses receive prompt diagnosis and rapid interventions in the NCCU. The Jefferson Manual for Neurocritical Care by renowned neurosurgeon Jack I. Jallo, neurointensive care physician Jacqueline S. Urtecho, and distinguished colleagues is a high-yield pocket resource ideal for the bedside care of patients with serious, life-altering diseases. Nineteen concise chapters encompass cerebrovascular, neuromuscular, oncologic, and traumatic conditions, as well as core clinical topics applicable to the care of neurocritical patients. Key Highlights Evidence-based management strategies created at Thomas Jefferson University's Vickie and Jack Farber Institute for Neuroscience presented in reader-friendly algorithms, pictures, and charts General chapters cover brain death, sodium dysregulation, nutrition, sedation, pain management, neuromonitoring, and ventilation strategies Disease-specific chapters featuring succinct, bulleted format include epidemiology, causes, diagnostic tests, treatment options, symptoms, common clinical presentation, risk factors, differential diagnoses, and more This manual is an indispensable resource for neurocritical care residents and fellows, NCCU nurses, nurse practitioners, physician assistants, general intensive care physicians, and neurointensivists. This book includes complimentary access to a digital copy on https://medone.thieme.com.

This issue of Neurosurgery Clinics, guest edited by Dr. R. Mark Richardson and Dr. Vasileios Kokkinos, will focus on Epilepsy Surgery: The Network Approach. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: History of the network approach in epilepsy surgery, Networks in temporal lobe epilepsy, Networks in frontal lobe epilepsy, Networks in parietal and occipital lobe epilepsy, Structures facilitating epileptogenic network formation, Extracranial interictal and ictal EEG in sEEG planning, Ictal semiology as a tool for sEEG planning, The significance of MRI lesions in sEEG planning, Functional networks in epilepsy presurgical evaluation, Automation advances in sEEG planning, Interpretation of the intracranial sEEG signal, Electrical cortical stimulation, Epileptogenic index, Modeling the epileptogenic network, Machine learning in epilepsy surgery evaluations, Neuromodulation of epilepsy networks, and Decision-making in epilepsy surgery.

This issue of Neurosurgery Clinics, guest edited by Dr. Mark H. Bilsky, will cover key topics in Spinal Oncology. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: Radiation Strategies for Chordoma, New Prospects for Molecular Targets in Chordoma, Surgical Strategies for Chordoma, State of the Art Treatment for Giant Cell Tumors, NOMS and Other Decision Frameworks for Metastatic Disease, Evolving Role of SBRT in Spine Metastases, Hybrid Therapy for Metastatic Disease, Interventional Hybrid Therapy for Metastatic Disease LITT and SBRT, MIS Strategies Changing the Treatment of Spine Tumors, Intradural Tumors, SBRT for Benign Spine Tumors, and Evolving Diagnostic Treatment Paradigms for Spine and Peripheral Nerve Manifestations of NF, among others.

This issue of Neurosurgery Clinics, edited by Drs. Shahid Nimjee and Russell Lonser, will cover Coagulation and Hematology in Neurological Surgery. Topics include Biology of coagulation and coagulopathy; Evaluation of the coagulation in the neurosurgery patient; Genetics of hyper- and hypo-coagulable states; Anticoagulants: pharmacokinetics, mechanisms of action and indications; Use of antiplatelet agents in the neurosurgical patient; Common conditions requiring long-term anti-coagulation in the neurosurgical patient; Reversal of systemic and antiplatelet anticoagulants; Intraoperative blood and factor replacement neurosurgery; Management of Intraoperative coagulopathy; Deep vein thrombosis prophylaxis in the neurosurgical patient; Postoperative anticoagulation after neurological surgery; Management of venous sinus thrombosis; Management of acute ischemic thrombosis; and Management of intracranial hemorrhage the anticoagulated patient.

This issue of Neurosurgery Clinics, edited by Drs. Sigurd Berven and Praveen V. Mummaneni, will cover Degenerative Spinal Deformity: Creating Lordosis in the Lumbar Spine. Topics will include, but are not limited to, Spinopelvic Parameters; Location of lordosis (priority for L4-S1) and Age Adjustments; Approach Selection; Nuances of Pedicle Subtraction Osteotomy; Preventing Pseudarthrosis and PJK; The Challenge of Creating Lordosis in High Grade Dysplastic Spondylolisthesis; Sacropelvic Fixation; Evolution of the MISDEF Algorithm; Transpsoas Approach Nuances; Lateral Prepsoas Approach Nuances; Anterior Column Release; Navigation assisted MIS deformity correction; MIS TLIF; MIS PSO; and The challenge of L4-S1- fractional curves.

This issue of Neurosurgery Clinics will focus on subdural hematomas. Articles will include: Imaging of Subdural Hematomas; Chronic Subdural Natural History; Chronic Subdural Medical Management; Chronic Subdural Minimally Invasive Surgery; Chronic Subdural Craniotomy; Chronic Subdural ICU Management; and many more!

An authoritative pocket-sized guide on the medical and surgical management of neurosurgical intensive care patients Decompression is still the mainstay of surgical intervention for neurosurgeons treating neurocritical care patients. However, during the last 20 years, an evolution away from a mechanistic approach has transformed neurocritical care into an increasingly multidisciplinary field. Neurosurgical Intensive Care, 2nd Edition reflects this new paradigm, authored by a neurosurgeon with contributions from experts in the fields of neurology, vascular neurology, interventional neuroradiology, anesthesiology, critical care, traumatology, nutrition, and advanced practice nursing. Neuromonitoring advances have enabled customized interventions tailored to each patient's unique circumstances. The critical care of neurosurgical patients has evolved from an emphasis on pulmonary care (ventilation and oxygenation) to a more nuanced understanding of cerebral protection measures required to manage a disrupted blood-brain-barrier. This edition encompasses advances in the use of ICP monitors, external ventricular devices, brain tissue oxygen monitoring devices, cerebral microdialysis, fluid and electrolyte correction, as well as the increasing use of continuous EEG in the ICU. Key Features Straightforward summaries for each stage of patient care including bedside exams, neuroimaging, lab work, triage procedures, sedation and pain management, neuropharmacology, nutritional needs, administration of fluids, and more. 159 tables and figures facilitate rapid evaluation and decision making. Clinical pearls on a wide range of ICU scenarios - from pathophysiology and management of coma - to interventions for spinal cord injury, multisystem injuries, acute ischemic stroke, and pediatric cases. Insights on how to handle family communication and spiritual needs, medical-legal issues, and discharge planning This compact, highly practical handbook provides a stellar reference for managing critically ill neurosurgical patients in the ICU. It is a must-have resource for nurses, medical students, residents, fellows, and attending physicians who treat these patients.

The consequences of a brain injury can affect all aspects of our lives, including our personality. Brain injuries do not heal like other injuries and symptoms may appear right away or may not be present for days or weeks after the injury. This issue will include Past, Present, and Future of TBI research; Pathophysiology of TBI; Advances in brain imaging of TBI; and many more articles leading up to Degenerative Disease following Traumatic Brain Injury.