In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

Meningiomas are the most frequently reported neuro-oncologic condition, accounting for 12% to 30% of all primary intracranial tumors. The first case of intracranial meningioma treated with stereotactic radiosurgery was reported by Backlund E-O in 1971. Since then, more than 200,000 meningiomas have been treated with stereotactic radiosurgery worldwide to date. The large number of patients treated using this method is due to the fact that meningiomas are frequently located in critical areas and microsurgery is often associated with severe and permanent neurological complications. This book discusses the advantages, risks and limits of stereotactic radiosurgery relating to all regions of interest for a neuroradiosurgical approach for the treatment of central nervous system meningiomas. Firstly, it presents an introduction focusing on the "state of the art". It then discusses the physics, imaging, neurological and neuro-oncological issues in multidisciplinary management. Lastly, it features a summary of results, including the most recent published papers regarding all the locations involved in the stereotactic radiosurgery treatment as well as new approaches to meningiomas, with particular reference to the hypofrationated treatments. Intended for anyone involved in the neuroradiosurgical treatment of brain diseases, the book provides an up-to-date overview of the latest stereotactic radiosurgery treatment of central nervous system meningiomas.

The objective of this 5th edition of the book, as with the prior editions, is to teach through images a practical approach to magnetic resonance (MR) physics and image quality. Unlike other texts covering this topic, the focus is on clinical images rather than equations. A practical approach to MR physics is developed through images, emphasizing knowledge of fundamentals important to achieve high image quality. Pulse diagrams are also included, which many at first find difficult to understand. Readers are encouraged to glance at these as they go through the text. With time and repetition, as a reader progresses through the book, the value of these and the knowledge thus available will become evident (and the diagrams themselves easier to understand). The text is organized into concise chapters, each discussing an important point relevant to clinical MR and illustrated largely with images from routine patient exams. The topics covered encompass the breadth of the field, from imaging basics and pulse sequences to advanced topics including contrast-enhanced MR angiography, spectroscopy, perfusion and advanced parallel imaging/data sparsity techniques. Discussion of the latest hardware and software innovations, for example next generation low field MR, deep learning, MR-PET, 7 T, interventional MR, 4D flow, CAIPIRINHA, spiral techniques, radial acquisition, simultaneous multislice, compressed sensing and MR fingerprinting, is included because these topics are critical to current clinical practice as well as to future advances. Included in the fifth edition are a large number of new topics, keeping the text up to date in this increasingly complex field. The text has also been thoroughly revised to include additional relevant clinical images, to improve the clarity of descriptions, and to increase the depth of content. The book is highly recommended for radiologists, physicists, and technologists interested in the background of image acquisition used in standard as well as specialized clinical settings.

This practical guide for trainees and advanced practice providers covers the essential management of hospitalized patients with acute neurologic conditions. Divided into five sections, this text serves as an incredibly easy-to-use, visually accessible, how-to manual that covers exactly what every responding clinician needs to know to care for the patient in front of them. The first section provides tangible guidance about how to pre-round, structure a presentation, examine neurologically ill patients, and interpret the core diagnostics obtained in many neurology patients: CT, MRI and EEG. The next three sections cover common complaints encountered in the hospital: spanning from non-vascular admissions, vascular & stroke neurology topics, and core neurocritical care principals and chief complaints. Throughout are checklists, scoring systems, pro-tips, images, helpful reminders, as well as concise summary of the pertinent literature. This is an ideal guide for medical students, neurology & neurosurgery trainees and advanced practice providers, as well as experienced professionals who want to brush up on the latest updates.

In this issue of Neurosurgery Clinics, Guest Editor James A. Stadler brings his considerable expertise to the topic of syndromic neurosurgery. Top experts in the field cover key topics such as Syndromic epilepsy, tumor syndromes, syndromic craniosynostosis, and more. Provides in-depth, clinical reviews on syndromic neurosurgery, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 14 relevant, practice-oriented topics including The history of syndromic neurosurgery; Multidisciplinary evaluation of neurosurgical patients with genetic syndromes; Neurosurgical evaluation and management of children with achondroplasia; Neurosurgical evaluation and management of patients with connective tissue disorders; and more.

A practical and succinct guide to neurophysiological monitoring for safer brain tumor surgery The surgical treatment of infiltrating brain tumors is an extremely challenging and often highly rewarding facet of neurosurgery. The decision-making process involves deeply human interconnections with patients and relatives, cutting-edge neuroscience, and fascinating technology. Video Atlas of Neurophysiological Monitoring in Surgery of Infiltrating Brain Tumors by renowned oncological neurosurgeon Michael Sabel and esteemed contributors demonstrates the practical applications of neurophysiological monitoring to achieve safe removal of infiltrating brain tumors in asleep and awake settings. Organized in three primary parts, the book starts with an introduction including a discussion of the impact and challenges posed by infiltrating gliomas and cerebral metastases and the philosophy behind supramarginal resection. The second part covers critical theoretical components including relevant anatomy, nervous system electricity and fields, transcranial monitoring methods and principles, and direct cortical and subcortical mapping including awake brain surgery. The final part provides insightful, practical guidance on decision making, monitoring set-up, planning of surgical cases, and a summary of accompanying videos. Key Highlights Discussion of impacted anatomy, physiology of the neural pathways monitored in brain tumor surgery, and key neurophysiological techniques for monitoring and testing during resection Instructive illustrations coupled with concise explanations enhance knowledge and facilitate understanding of techniques Fifteen videos covering real-life intraoperative cases provide in-depth insights on applying IONM principles to infiltrating brain tumors This is an essential resource for any neurosurgeon involved or interested in brain tumor surgery, from residents and fellows to board-certified neurosurgeons not yet trained in this field. This book includes complimentary access to a digital copy on https://medone.thieme.com.

This issue of Neurosurgery Clinics, guest edited by Dr. Domagoj Coric, provides an Update on Motion Preservation Technologies. This issue is one of four selected each year by our series consulting editors, Drs. Russell R. Lonser and Daniel K. Resnick. This issue discusses state-of-the-art indications, technique, devices, complications and evidence basis for motion preserving technologies in the cervical and lumbar spines. Topics covered in this issue will include: Cervical Total Disc Replacement: Indications and Technique, Cervical Total Disc Replacement: Off-label and Expanded Indications, Cervical Total Disc Replacement: FDA-approved Devices, Cervical Total Disc Replacement: Novel Devices, Cervical Spine Surgery: Arthroplasty versus Fusion versus Posterior Foraminotomy, Cervical Total Disc Replacement: Complications and Complication Avoidance, Cervical Total Disc Replacement: Long-term Outcomes, Biomechanics of Cervical Arthroplasty Devices, Adjacent-level Disease following Spinal Arthroplasty, Lumbar Total Disc Replacement: Current Usage, and Posterior Lumbar Facet Replacement and Arthroplasty. Provides in-depth, clinical reviews on the latest updates in Motion Preservation Technologies, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

This book is a detailed resource on the technical aspects of pediatric neurosurgery that relate to vascular malformations of the brain and spinal cord. It introduces concepts relevant to cerebrovascular system development and the classification of vascular malformations. Information on a range of disorders is then provided with an emphasis placed on answering frequently asked questions in relation to a particular condition. Therefore, enabling the reader to systematically improve their understanding of how approach treating patients utilizing techniques such as ultrasound and spinal angiography. The chapters, authored by experts in their respective field, provide a standard of care based on current diagnostic and management guidelines for pediatric neurosurgical diseases. Pediatric Vascular Neurosurgery: Technical Nuances in Contemporary Pediatric Neurosurgery (Part 2) is a comprehensive overview of how to approach diagnosing and treating a range of vascular malformations encountered in pediatric patients. The problem-solving approach of this work makes it a valuable addition to the literature and suitable for use by residents, fellows and consultants within pediatrics and allied specialities, including Neurosurgery, Neurology, Neuro-anesthesia, Neuro-critical care and advanced health care providers amongst others.

Das vorliegende Werk liefert das Basiswissen fur die Versorgung des internistischen Intensivpatienten - systematisch dargestellt, verstandlich erklart und mit vielen konkreten Tipps. Es wendet sich an Assistenzarzte in der Inneren Medizin, die im Rahmen ihrer Facharztweiterbildung auf die Intensivstation rotieren mussen und eine erste Anleitung fur die Arbeit auf der Intensivstation benoetigen. Dargestellt werden allgemeinen Prinzipien, wie apparative Diagnostik, Ernahrung und Gerinnungsmanagement uber spezielle Interventionen, wie Gefasspunktionen, Schrittmacheranlage und Analgosedierung bis hin zum konkreten Vorgehen bei haufigen intensivpflichtigen Krankheitsbildern und Akutsituationen, wie akutes Koronarsyndrom, Herzrhythmusstoerungen, ARDS und Intoxikationen. Ein praxisnahes Werk, mit dem der Einstieg in die internistische Intensivmedizin gelingt.

This issue of Neurosurgery Clinics, guest edited by Drs. Edjah Nduom and Jeff Olson, will focus on Metastases to the Central Nervous System. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: Epidemiology of metastatic CNS disease, Initial approach to the patient with a newly diagnosed solitary brain metastasis, Initial approach to the patient with multiple newly diagnosed brain metastases, When to consider a stereotactic biopsy for brain metastases, Techniques for open surgical resection of cerebral metastases, Laser ablation for cerebral metastases, Histopathological features and laboratory markers of common brain metastases, Recurrence vs radiation necrosis - evaluation and treatment, Anti-epileptic drugs for the management of cerebral metastases, Chemotherapy for the management of cerebral metastases, Approach to the management of metastatic leptomeningeal disease, Immune therapy for CNS metastases, Novel therapeutic targets for the treatment of cerebral metastases, Skull base metastases - diagnosis and management, and more.

The book is a practical guide for neurosurgeons and radiation oncologists willing to better understand the contemporary multimodal management of neurosurgical diseases including, but not limited to, stereotactic radiosurgery (SRS). Since its invention 1950s, SRS has dramatically impacted the treatment and prognosis of several neurosurgical diseases such as brain and spine metastases, intracranial and spinal arteriovenous malformations, benign head and spine tumors, functional neurological diseases, etc. The book is formed by 35 chapters encompassing all aspects of SRS, from basic principles to the traditional and novel clinical applications. Each chapter points out the current evidence-based indications, contraindications, and adverse effects of SRS and other techniques that should be considered as an alternative or as a complement to SRS.

Seven Bypasses: Tenets and Techniques for Revascularization is the third book in a trilogy of bravura, technical nuance, and strategy by master neurosurgeon Michael Lawton. Like his first two books on aneurysms and AVMs, Seven Bypasses provides unparalleled firsthand insights and guidance on complex pathologies in vascular neurosurgery. The fundamentals of microsurgical anastomosis and the craft of bypass surgery are explored in depth with clinical pearls in every chapter. Lawton eloquently reveals the art of cerebral revascularization in exquisite, metaphorical detail. The surgeon performing bypass surgery is like an architect envisioning and building a beautiful structure. A bypass is designed to fit the patient's unique anatomy; blueprints designate anastomotic sites, connections, and conduits; the anastomoses are constructed; and the bypass is brought to life with pulsations, flow, and reperfusion. The book highlights Lawton's aesthetic, which has evolved from the common STA-MCA bypasses to IC-IC bypasses and elaborate arterial reconstructions. Key Highlights Stepwise discussion of the three anastomoses that form the building blocks of all bypasses: end-to-side, side-to-side, and end-to-end anastomoses Ten tenets delineate nuances of bypass: dexterity, preparing donors and recipients, establishing a working zone, temporary arterial occlusion, arteriotomy, suturing technique, tissue handling, knot tying, patency, and aneurysm occlusion Step-by-step guidance on the seven bypasses: EC-IC bypass, EC-IC interpositional bypass, arterial reimplantation, in-situ bypass, reanastomosis, IC-IC interpositional bypass, and combination bypass Strategies and algorithms for aneurysms organized by specific anatomical sites, including the MCA and the Sylvian cistern, ACA and the interhemispheric cistern, basilar artery and the basal cisterns, and PICA and the cisterna magna More than 1,500 radiographs, operative photographs, and exquisite illustrations drawn by artist Kenneth Xavier Probst elucidate anatomy, surgical principles, and clinical cases Dr. Lawton has bequeathed a remarkable treasure of knowledge to current and future generations of neurosurgeons and their patients. The Seven series is destined to be an enduring classic for residents, fellows, and neurosurgeons specializing in the treatment of cerebrovascular disease, and for those who believe that manual dexterity and technical skill still matter.

Pocket Atlas of Spine Surgery, 2nd Edition by Kern Singh and Alexander Vaccaro is unique in its presentation, utilizing multilayered visuals to delineate the most commonly performed spine procedures. High-definition intraoperative photographs are juxtaposed with translucent anatomic drawings. This facilitates visualization of both the entire surgical field and complex anatomy never "seen" during surgery. It also provides greater insights into the subtleties of both open and technically demanding minimally invasive spine surgery techniques. Unlike many large spine surgery atlases, this is the perfect, on-the-go, pocket-size resource for busy spine surgeons who work in any clinical setting. From the cervical to lumbar spine, 21 concise chapters reflect the collective technical expertise of internationally renowned spine surgeons. Easy-to-follow guidance is provided on fundamental open and minimally invasive techniques, including pedicle screw placement, fusion, discectomy, corpectomy, foraminotomy, laminoplasty, and laminectomy. Each procedural chapter focuses on the importance of accurate visualization, adequate homeostasis, and impacted anatomical structures. Insightful tips, pearls, and potential pitfalls throughout the book expedite acquisition of knowledge Nearly 200 detailed, clearly labeled images of common spine procedures provide invaluable anatomical and clinical guidance Expanded insights on positioning in spine surgery Added discussion of surgical challenges, including warnings and descriptions of internervous planes Orthopaedic surgeons, neurosurgeons, and surgical trainees will discover an indispensable and friendly white coat reference for everyday practice. The visually rich atlas will also benefit physician assistants, surgical nurses, and all practitioners involved in the operative care of spine surgery patients.

Part of the Neurosurgery by Example series, this volume on functional neurosurgery presents exemplary cases in which renowned authors guide readers through the assessment and planning, decision making, surgical procedure, after care, and complication management of common and uncommon disorders. The cases explore the spectrum of clinical diversity and complexity within functional neurosurgery, including essential tremor, thalamotomy, parkinson's disease, epilepsy, dystonia, and more. Each chapter also contains 'pivot points' that illuminate changes required to manage patients in alternate or atypical situations, and pearls for accurate diagnosis, successful treatment, and effective complication management. Containing a focused review of medical evidence and expected outcomes, Functional Neurosurgery is appropriate for neurosurgeons who wish to learn more about a subspecialty, and those preparing for the American Board of Neurological Surgery oral examination.

Das vorliegende Buch prasentiert das gesamte klinische und wissenschaftliche Spektrum der neurologischen Beatmungsmedizin. Es wendet sich an alle AErzte, die beatmete neurologische Patienten betreuen, wie Neurologen, Anasthesisten, Internisten, Pneumologen, Intensivmediziner, Schlafmediziner und Palliativmediziner. Das Werk vermittelt sowohl die fur die neurointensivmedizinische und neurorehabilitative Behandlung als auch die fur die optimale Versorgung ausserklinisch beatmeter Patienten erforderlichen Kenntnisse. Zahlreiche Handlungsempfehlungen fur das Vorgehen bei den oft schwierigen Beatmungs- und Atemwegssituationen machen das Werk besonders praxistauglich.

This issue of Neurosurgery Clinics, guest edited by Dr. Nathaniel P. Brooks and Dr. Michael Y. Wang, is devoted to New Technologies in Spine Surgery. Articles in this issue include: Endoscopic Lumbar Discectomy, Endoscopic Cervical Foraminotomy, Endoscopic Lumbar Interbody Fusion, Endoscopic Lumbar Decompression, Lateral Lumbar Interbody Fusion, Retropleural Thoracic Approach, Novel Intervertebral Technologies, Surface Technologies for Fusion, Cell derived/Stem Cell Technologies for Fusion, Disk Replacement, Enhanced Recovery in Spine Surgery/Perioperative pain management, Imaging Technologies, Robotic Instrumentation Placement, Minimally Invasive Deformity Advances, Tissue Engineering/Regenerative Treatments, Minimally Invasive Tumor Ablation, and more.

This issue of Neurosurgery Clinics, guest edited by Drs. Wendell B. Lake, Ashwini D. Sharan, and Chengyuan Wu, will focus on Neuromodulation. Topics include, but are not limited to, Deep brain stimulation for Parkinson's disease, Deep Brain Stimulation for Essential Tremor, Deep Brain Stimulation for Dystonia, Spinal Cord Stimulation, Baclofen Pumps for Spasticity and Secondary Dystonia, Occipital Nerve Stimulation, Vagal Nerve Stimulation for the treatment of Epilepsy, Responsive Neurostimulation for the treatment of Epilepsy, Emerging Indications for Deep Brain Stimulation, Peripheral Nerve Stimulation for Pain, Brain computer interface.

This issue of Neurosurgery Clinics, edited by Dr. Michael G. Fehlings and Dr. Junichi Mizuno, focuses on Cervical Myelopathy. Topics include, but are not limited to, Epidemiology and overview of the clinical spectrum of degenerative cervical myelopathy; Pathobiology of degenerative cervical myelopathy; Natural history of degenerative cervical myelopathy; Imaging evaluation of degenerative cervical myelopathy: current state of the art and future directions; Pathophysiology of CPPD and OYL(OLF); Radiological evaluation of OPLL with dural ossification; Relationship of OALL, OPLL and OYL (OLF); Importance of sagittal alignment of the cervical spine in the management of degenerative cervical myelopathy; Anterior cervical options to manage degenerative cervical myelopathy; Laminectomy with or without fusion to manage degenerative cervical myelopathy; History and evolution of laminoplasty; Prediction of outcomes in managing degenerative cervical myelopathy; Neurological complications in managing degenerative cervical myelopathy; Options to manage the patient with mild degenerative cervical myelopathy; Management of the patient with cervical cord compression but no evidence of myelopathy; Intraoperative neurophysiological monitoring for CDD; Future Directions and New Technology, and more!

This issue of Neurosurgery Clinics focus on Intraoperative Imaging. Article topics will include historical, current and future intraoperative imaging modality; iMRI suites: history, design, utility and cost-effectiveness; Stereotactic platforms for iMRI; iMRI for tumor: maximizing extent of resection of glioma; IMRI for tumor: combining iMRI with functional MRI; iMRI for tumor: pituitary adenoma; iMRI for tumor: MR thermometry; iMRI for tumor: LITT for spinal tumors; iMRI for functional/epilepsy neurosurgery: DBS placement; iMRI for functional/epilepsy neurosurgery: MR thermometry for mesial temporal epilepsy; iMRI for functional/epilepsy neurosurgery: MR thermometry HIFU; Fluorescence imaging/agents in tumor resection; Intraoperative 3D ultrasound; Intraoperative 3D CT: spine surgery; Intraoperative 3D CT: cranial/functional/trigem; Intraoperative imaging for vascular lesions; Imaging of intraoperative drug delivery; Intraoperative ultrasound for peripheral nerve; and Intraoperative Raman Spectroscopy.

Dating Neurological Injury: A Forensic Guide for Radiologists, Other Expert Medical Witnesses, and Attorneys presents a unique way to approach the dating of neurological injury as imaged by modern computed tomography (CT), magnetic resonance (MR) and ultrasound (US). Chapters are presented in a logical progression beginning with the general appearance of normal brain and progressing to the way abnormalities manifest themselves. The emphasis in these discussions is on the appearance of edema and of hemorrhage, as these two findings are the brain's most common response to injury. This volume presents in a systematic fashion the principles involved in the interpretation of images of the central nervous system specifically in a medical-legal setting where concern exists about the occurrence and timing of an injury. Dating Neurological Injury: A Forensic Guide for Radiologists, Other Expert Medical Witnesses, and Attorneys is a welcome addition to institutional, medical, and legal libraries, and to the personal libraries of malpractice defense and plaintiff lawyers and physicians in the neurosciences (neurosurgery, neurology, neuropathology, and neuroradiology) involved in medical-legal issues.

This issue of Neurosurgery Clinics focuses on Controversies in Spinal and Cranial Surgery. Article topics will include:Sacro-illiac Fusion; Interspinous Spacers;Bone Morphogenetic Protein, Platelet Concentrates and Other Biologics; MIS decompression; Pipeline flow diversion in subarachnoid hemorrhage; Direct versus indirect bypass for moyamoya disease; Management of prenatally diagnosed myelomeningocele; Management of incidental aneurysm; Surgical management of incidental low-grade glioma; and more!

This issue will focus on both adult and pediatric spine trauma. Featured articles are as follows: Pharmacologic Treatment of SCI; Classification of Adult Subaxial Cervical Trauma; Classification and Management of Pediatric Craniocervical Injuries; Classification and Management of Pediatric Subaxial Injuries; Classification of Adult Thoracolumbar Injuries; Management of Pediatric Thoracolumber Injuries; Treatment of Odontoid Fractures in the Aging Population; Treatment of Facet Fractures in the Cervical Spine; and many more!