One of the greatest public health achievements during the 20th century was the dramatic reduction in the incidence of infectious diseases due to the development of improved hygiene, vaccines, and antimicrobial agents. However, new infectious diseases are emerging and bacteria-induced illnesses - such as tuberculosis, whooping cough, and typhoid fever - are still a major cause of global mortality. In recent decades, the development of molecular biology and genetic tools has led to extensive studies on the molecular and cellular aspects of the virulence properties of pathogenic bacteria. In this book, a group of distinguished scientists from eight different countries and three continents, under the expert guidance of the editors Camille Locht and Michel Simonet, overview the molecular and cellular mechanisms of bacterial pathogenesis. The 15 chapters are organized into five sections: a) approaches to the study of bacterial pathogenesis; b) bacterial adhesion to the cell surface and extracellular matrix of host tissues; c) poisoning the host by toxins; d) cellular invasion by bacterial pathogens; and e) bacterial evasion of host defenses. The book comprehensively describe the most relevant and up-to-date information on pathogenic features across the bacterial world. Aimed at the entire scientific community from students to senior scientists and physicians, Bacterial Pathogenesis is relevant to a broad range of people interested in the mechanisms of bacterial infectious diseases and is a recommended text for all microbiology laboratories.

This collection of essays examines the way psychoactive substances are described and discussed within late eighteenth- and nineteenth-century British literary and cultural texts. Covering several genres, such as novels, poetry, autobiography and non-fiction, individual essays provide insights on eighteenth- and nineteenth-century understandings of drug effects of opium, alcohol and many other plant-based substances. Contributors consider both contemporary and recent medical knowledge in order to contextualise and illuminate understandings of how drugs were utilised as stimulants, as relaxants, for pleasure, as pain relievers and for other purposes. Chapters also examine the novelty of experimentations of drugs in conversation with the way literary texts incorporate them, highlighting the importance of literary and cultural texts for addressing ethical questions.

Assessing, Diagnosing, and Treating Serious Mental Disorders uniquely provides information that is useful across mental health, psychopathology, practice, and human behavior and development classes, particularly for psychopathology and advanced mental health practice courses. DSM-IV-TR diagnostic criteria is provided for each mental disorder discussed in the textbook. This book represents a new wave of social work education, focusing on mental disorders as an interaction among neurobiology, genetics, and ecological social systems. Edward Taylor argues that most all mental disorders have a foundation within the person's brain that differentially interacts with the social environment. Therefore, how the brain is involved in mental disorders is covered far more comprehensively than found in most social work textbooks. However, the purpose is not to turn social workers into neuroscientists, but to prepare them for educating, supporting, and where appropriate providing treatment for, clients and families facing mental illness. Entire chapters are dedicated to explaining bioecological and other related theories, family support and intervention, and assessment methods. To help students conceptualize methods, the book includes specific steps for assessing needs, joining, and including families in mental health treatment decisions. Methods for helping families become part of the treatment team and for providing in-home interventions are highlighted. Throughout the book, readers can find helpful outlines and illustrations for how to understand, assess, and treat mental disorders.

Edited by Stephanie W. Cawthon and Carrie Lou Garberoglio, Research in Deaf Education: Contexts, Challenges, and Considerations is a showcase of insight and experience from a seasoned group of researchers across the field of deaf education. Research in Deaf Education begins with foundational chapters in research design, history, researcher positionality, community engagement, and ethics to ground the reader within the context of research in the field. Here, the reader will be motivated to consider significant contemporary issues within deaf education, including the relevance of theoretical frameworks and the responsibility of deaf researchers in the design and implementation of research in the field. As the volume progresses, contributing authors explore scientific research methodologies such as survey design, single case design, intervention design, secondary data analysis, and action research at large. In doing so, these chapters provide solid examples as to how the issues raised in the earlier groundwork of the book play out in diverse orientations within deaf education, including both quantitative and qualitative research approaches. Designed to help guide researchers from the germ of their idea through seeing their work publish, Research in Deaf Education offers readers a comprehensive understanding of the critical issues behind the decisions that go into this rigorous and important research for the community at hand.

Substance use and substance use disorders (SUDs) have been documented in a number of cultures since the beginnings of recorded time and represent major societal concerns in the present day. The Oxford Handbook of Substance Use and Substance Use Disorders provides comprehensive reviews of key areas of inquiry into the fundamental nature of substance use and SUDs, their features, causes, consequences, course, treatment, and prevention. It is clear that understanding these various aspects of substance use and SUDs requires a multidisciplinary perspective that considers the pharmacology of drugs of abuse, genetic variation in these acute and chronic effects, and psychological processes in the context of the interpersonal and cultural contexts. Comprising two volumes, this Handbook also highlights a range of opportunities and challenges facing those interested in the basic understanding of the nature of these phenomena and novel approaches to assess, prevent, and treat these conditions with the goal of reducing the enormous burden these problems place on our global society. Chapters in Volume 1 cover the historical and cultural contexts of substance use and its consequences, its epidemiology and course, etiological processes from the perspective of neuropharmacology, genetics, personality, development, motivation, and the interpersonal and larger social environment. Chapters in Volume 2 cover major health and social consequences of substance involvement, psychiatric comorbidity, assessment, and interventions. Each chapter highlights key issues in the respective topic area and raises unanswered questions for future research. All chapters are authored by leading scholars in each topic. The level of coverage is sufficiently deep to be of value to both trainees and established scientists and clinicians interested in an evidenced-based approach.

Many will remember the segment of "The Sorcerer's Apprentice" in the Disney film Fantasia; it is a perfect metaphor for medical imaging as it stands today. The apprentice magician tests his nascent skills at sorcery by bringing common household items to life and putting them to work. At first, things go well, but eventually he loses control, and chaos ensues.
Medical imaging, too, could spin out of control. The benefits of imaging are undeniable. In the past thirty years, innovations like CT, MRI, and PET scanning have not only markedly reduced clinical risk for patients but have also transformed medical practice. Its costs, however, have grown explosively, to the point where imaging expenses have become a political issue. The aggressive adoption of imaging technology has raised issues about the role of inappropriate economic incentives and the role of defensive medicine in driving up medical costs.
Radiologists have utilized imaging technology to transform their practice from a pure diagnostic discipline into a curative one. Radiologists are among the most successful knowledge workers in the entire economy, leveraging digital information technology and Internet connectivity to become the first global medical discipline. Imaging is poised to make a further quantum advance - into the workings of the human cell and the molecular biology of complex disease.
Where is this remarkable technology, and the discipline which uses it, headed? How can society make the most responsible use of this powerful new tool? How will imaging and radiologists reshape medical practice? These questions will be answered by The Sorcerer's Apprentice.

As a physician who personally suffers from depression, Susan J. Noonan draws on her own expertise and empathy to create a guide for people who suffer from the disease. Explaining the basics of mental health-including sleep hygiene, diet and nutrition, exercise, routine and structure, and avoiding isolation - "Managing Your Depression" empowers people to participate in their own care, offering them a better chance of getting, and staying, well. Noonan's depression management strategies draw on the best available educational resources, psychoeducational programs, seminars, expert health care providers, and patient experiences. The book is specifically designed to be highly readable for people who are finding it difficult to focus and concentrate during an episode of depression. Cognitive exercises and daily worksheets help track progress and response to therapy and provide valuable information for making treatment decisions. A relapsing and remitting condition, depression affects nearly 15 percent of people in the United States. "Managing Your Depression" will bring depression management strategies to people who do not have access to mental health programs or who want to learn new skills.

In this book, a multidisciplinary and international selection of Jungian clinicians and academics discuss some of the most compelling issues in contemporary politics. Presented in five parts, each chapter offers an in-depth and timely discussion on themes including migration, climate change, walls and boundaries, future developments, and the psyche. Taken together, the book presents an account of current thinking in their psychotherapeutic community as well as the role of practitioners in working with the results of racism, forced relocation, colonialism, and ecological damage. Ultimately, this book encourages analysts, scholars, psychotherapists, sociologists, and students to actively engage in shaping current and future political, socio-economic, and cultural developments in this increasingly complex and challenging time.

Psychoanalysis and the Politics of Family aims to raise a sophisticated and highly accessible debate around the family, self-making and the political and cultural implications of liberation. The text proposes a new way to read the Lacanian theory of Oedipus and through this reading resituate a series of important political and theoretical debates that have concerned intellectual life over the last forty years. It is written with an accessible style so that both specialists in Lacanian and Marxist theory and a broader cross-section of readers interested in understanding the implications of debates across populist and Marxist perspectives that have occupied the global left since the 2008 economic crash. The text aims to resituate the way theories of emancipation and liberation are theorized from a distinctive psychoanalytic and Lacanian point of view. In resituating the infamous "Oedipus complex" in a new light, the text re-opens a series of debates with important theoretical interlocutors, including the influential American historian and psychoanalytic thinker Christopher Lasch, whose thought has witnessed a significant renaissance of interest today, to the staunch critic of Freud and Lacan, Rene Girard, to Gilles Deleuze and Felix Guattari and their widely read Anti-Oedipus series that disputes the Freudian and Lacanian notions of Oedipus.

Psychotherapy, in order to survive, must shift from curing to caring. The pathological model is giving way to the growth model. Finding wholeness in our confusion requires imagination and transcendence. Healing requires more than self-knowledge and awareness. Only through experiencing oneself, in a struggle of mutual acceptance, are the blocks to the life force removed. The book is about being fully alive. It leads to the thinking of the most profound psychotherapy into the next century. Existentialism is the framework by which the author addresses our deepest life needs. It alone gives meaning to our experience. A seasoned and thoughtful clinician, the author furnishes rich techniques and approaches toward a new understanding of patients' life dilemmas. His solid and dramatic case material shows how he keeps himself and his patients deeply engaged in experiencing life in abundance. This nourishing book will lead both therapist and client away from burnout into deeper lives of optimism, freshness and creativity.

"Dr. Feldmar's book is jam-packed with interesting information. You will get a basic understanding of how and why we, and the people around us, behave the way we do. A must-have book for any personal library." - Louis Puglisi, MA "I found Dr. Feldmar's book to be very informative. He cuts through the professional jargon, and makes it easily understandable for the lay person. It is an invaluable reference book for every household." - Gabor Kovacs, MD, FACS "After reading Dr. Feldmar's book, I feel it should be mandatory reading for all parents. In a world of confusion about psychological labels, this book gives the reader a clear understanding of the problems and conditions we all face. For those of us dealing with people under stress at work or home, this book is a valuable tool." - Edward M. Portnoy, DMD "As a health care professional, I know it is important for patients and their families to become educated consumers in recognizing and dealing with abnormal psychological or psychiatric conditions. With the assistance of Dr. Feldmar's comprehensive and easy-to-read book, individuals will hopefully seek professional treatment sooner and be willing to partner with their health care providers to achieve a more successful outcome." - Roberta Kiel, RN, MPH

This book provides up-to-date information on the state of the art in applications of biotechnological and microbiological tools for protecting the environment. Written by leading international experts, it discusses potential applications of biotechnological and microbiological techniques in solid waste management, wastewater treatment, agriculture, energy and environmental health. This second volume of book "Environmental Microbiology and Biotechnology," covers two main topics: bioenergy and environmental health, exploring the latest developments from around the globe regarding applications of biotechnology and microbiology for converting wastes into valuable products and at the same time reducing the environmental pollution resulting from disposal. Wherever possible it also includes real-world examples. Further, it offers advice on which procedures should be followed to achieve satisfactory results, and provides insights that will promote the transition to the sustainable utilization of various waste products.

Renee Moreau Cunningham's unique study utilizes the psychology of C. G. Jung and the spiritual teachings of Mahatma Gandhi and Martin Luther King, Jr. to explore how nonviolence works psychologically as a form of spiritual warfare, confronting and transmuting aggression. Archetypal Nonviolence uses King's iconic march from Selma to Montgomery, a demonstration which helped introduce America to nonviolent philosophy on a mass scale, as a metaphor for psychological and spiritual activism on an individual and collective level. Cunningham's work explores the core wound of racism in America on both a collective and a personal level, investigating how we hide from our own potential for evil and how the divide within ourselves can be bridged. The book demonstrates that the alchemical transmutation of aggression through a nonviolent ethos, as shown in the Selma marches, is important to understand as a beginning to something greater within the paradox of human violence and its bedfellow, nonviolence. Archetypal Nonviolence explores how we can truly transform hatred by understanding how it operates within. It will be of great interest to Jungian analysts and analytical psychologists in practice and in training, and to academics and students of Jungian and post-Jungian studies, American history, race and racism, and nonviolent movements.

The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. A needed reference for entry level researchers and researchers working in interdisciplinary / collaborative projects, Peptide and Protein Delivery addresses the current and emerging routes for delivery of therapeutics. Covering cerebral delivery, pulmonary delivery, transdermal delivery, intestinal delivery, ocular delivery, parenteral delivery, and nasal delivery, this resource offers an overview of the main routes in therapeutics. Researchers across biochemistry, pharmaceutical, molecular biology, cell biology, immunology, chemistry and biotechnology fields will find this publication invaluable for peptide and protein laboratory research.
Discusses the most recent data, ideas and conceptsPresents case studies and an industrial perspectiveDetails information from the molecular level to bioprocessingThought provoking, for the novice to the specialistTimely, for today's biopharmaceuticals market