'Through different voices and styles of contributions, including papers, edited talks and panel discussion, this collection explores and applies the principles of relational transactional analysis. It sets them in social, cultural and political contexts, and considers a number of important implications of this particular relational turn in psychotherapy. The book advances relational transactional analyses and, in doing so, reflects the creativity and vibrancy of contemporary TA. The editors have skilfully brought together different generations of TA practitioners in an accessible and stimulating volume. I commend the editors and highly recommend the book.'- Dr Keith Tudor, author of a number of books and co-author of the article "Co-creative transactional analysis" in the Transactional Analysis Journal. He is Associate Professor, Auckland University of Technology, Auckland, Aotearoa, New Zealand.

Marek's disease virus (MDV) is a herpesvirus which causes a lymphoproliferative disorder of the domestic chicken worldwide. This serious economical problem caused by MDV was mostly solved by development of an effective vaccine against MDV. The development of live vaccines against the disease is remarkable as it has led to the first example of a commercially available vaccine against cancer as well as against diseases caused by herpesviruses.This volume gives an overview on many aspects of MDV research and summarizes recent advances in the field. The topics include the history, biology,and molecular biology of MDV, pathogenesis, vaccinal immunity, immune response, genetic resistance and development of recombinant polyvalent vaccines. It is hoped that this volume will make an important contribution towards the control of infectious diseases.

This book highlights important techniques for cellular imaging and covers the basics and applications of electron tomography and related techniques. In addition, it considers practical aspects and broadens the technological focus by incorporating techniques that are only now becoming accessible (e.g. block face imaging). The first part of the book describes the electron microscopy 3D technique available to scientists around the world, allowing them to characterize organelles, cells and tissues. The major emphasis is on new technologies like scanning transmission electron microscopy (STEM) tomography, though the book also reviews some of the more proven technologies like electron tomography. In turn, the second part is dedicated to the reconstruction of data sets, signal improvement and interpretation

This book offers a summary and discussion of the advances of inflammation and infection in various cancers. The authors cover the classically known virus infections in cancer, novel roles of other pathogens (e.g. bacteria and fungi), as well as biomarkers for diagnosis and therapy. Further, the chapters highlight the progress of immune therapy, stem cells and the role of the microbiome in the pathophysiology of cancers. Readers will gain insights into complex microbial communities, that inhabit most external human surfaces and play a key role in health and disease. Perturbations of host-microbe interactions often lead to altered host responses that can promote cancer development. Thus, this book highlights emerging roles of the microbiome in pathogenesis of cancers and outcome of therapy. The focus is on mechanistic concepts that underlie the complex relationships between host and microbes. Approaches that can inhibit infection, suppress chronic inflammation and reverse the dysbiosis are discussed, as a means for restoring the balance between host and microbes. This comprehensive work will be beneficial to researchers and students interested in infectious diseases, microbiome, and cancer as well as clinicians and general physiologists.

The second of two companion books which address the biology and clinical aspects of prostate cancer. This volume, Prostate Cancer: Molecular & Diagnostic Imaging and Treatment Stategies, discusses both classic and the most recent imaging approaches for detection, early diagnosis and treatment of prostate cancer. The companion title, Cell & Molecular Biology of Prostate Cancer, covers classic and modern cell and molecular biology as well as genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis, progression to metastasis, and treatment strategies including clinical trials related to prostate cancer. Taken together, these volumes form one comprehensive and invaluable contribution to the literature.

The book starts with a general introduction into the relevance of systems biology for understanding tuberculosis. This will be followed by several chapters which describe the application of systems biology to various aspects of the study of the pathogen, Mycobacterium tuberculosis, and its interaction with the host. The book provides the reader with an account of how the new science of systems biology is providing novel insights into the ancient scourge of tuberculosis. It will also describe how systems biology can be applied to the control of tuberculosis, including the development of new treatments, vaccines and diagnostics.

Interventional Oncology is a fast-growing new field, as well as an emerging specialty. Many minimally-invasive, imaging-guided procedures seem set to replace more traditional open surgical techniques of treating solid tumors in a variety of organs. The aim of this book is to describe new interventional radiological methods in a succinct and practical form. Diagnostic radiological considerations relevant to the selection and follow-up of patients are also covered. The book begins with an overview of the basic principles of current interventional techniques, including thermal ablation, high intensity focused ultrasound, and embolization. Later chapters focus on tumors of the liver, kidney, lung, and bone, placing new interventional techniques in context by referring to the surgical and oncologic methods of treating the same conditions. With an emphasis on best practices, Interventional Oncology: A Practical Guide for the Interventional Radiologist will serve as a definitive guide to practicing physicians involved in this rapidly evolving field.

This book presents a comprehensive overview of Asian families residing in Canada and the United States by portraying and analyzing Asian Canadian and Asian American immigrant families in an integrated yet nuanced way. Chapters use an interdisciplinary approach to provide more comprehensive coverage of the vast diversity as well as common trends and shared characteristics of Asian families. Specifically, the volume examines the experiences of families whose ancestry can be traced to East Asia, Southeast Asia, South Asia, and West Asia. Key areas of coverage include: Integrated overview of Asian American and Asian Canadian families, including an exploration of the historical and current immigration policies. Experiences of families of East Asian, Southeast Asian, South Asian, and West Asian ancestry across Canada and the United States. Asian religious traditions and worldviews, traditional practices, and religio-cultural views on gender, sexuality, and family. Specific Asian immigrant groups on immigration demographics, family dynamics and relationships, gendered roles, parenting practices and beliefs, and implications for mental health. Challenges and issues that families face as Asians and immigrants, the strength and resilience of families, with extensive reviews on various intervention and prevention programs. Methodological strategies in investigating Asian families and their impact on the field. Asian Families in Canada and the United States is a must-have resource for researchers, professors, graduate students as well as clinicians, professionals, and policymakers in the fields of developmental, social, and cross-cultural psychology, parenting and family studies, social work, and all interrelated disciplines.

Aimed at students, researchers, nutritionists, and developers in food technology, this research text addresses the nascent field of metabiotics. Metabiotics are products based on components of cells, metabolites, and signaling molecules released by probiotic strains, engineered to optimize host-specific physiological functions in a way that traditional probiotics cannot. This book examines the history, processes, design, classifications, and functions of metabiotics. It includes an overview of the composition and function of the gut microbiota, and discusses development of target-specific metabiotics. Further coverage includes comparisons to traditional probiotics, as well as probiotic safety and side-effects. Metabiotics: Present State, Challenges and Perspectives provides a complete history and understanding of this new field, the next phase of the probiotic industry.

1. Einfuhrung in die schlafendokrine Regulation.- 1.1 Schlaf - ein dynamisches Verhalten.- 1.2 Schlaf und Depression.- 1.3 Das Schlaf EEG - Grundlage der Untersuchung der Schlafregulation.- 1.31 Das Schlaf EEG.- 1.32 Die Schlafregulation.- 1.4 Die schlafendokrine Regulation.- 1.41 Bisherige Untersuchungen zur Rolle von Alter und Geschlecht fur die schlafendokrine Regulation bei gesunden Kontrollpersonen.- 1.5 Schlafendokrine Veranderungen bei Patienten mit Major.- 1.51 Veranderungen der Schlafregulation bei Patienten mit.- 1.52 Neuroendokrine Veranderungen bei Patienten mit Major.- 1.53 Bisherige Untersuchungen zur Rolle von Alter und Geschlecht fur die schlafendokrine Regulation bei Patienten mit Major Depression.- 2 Methodologie.- 2.1 Ethische Aspekte.- 2.11 Patienten und Probanden.- 2.2 Studiendesign.- 2.3 Behandlungen.- 2.31 CRH.- 2.32 GHRH.- 2.33 Kortikosteroide.- 2.4 Schlaf-EEG Untersuchung.- 2.5 Hormonmessungen.- 2.6 Statistische Methoden.- 3 Zusammenfassung der eigenen experimentelle Studien.- 4 Zusammenfassung und abschliessende Diskussion.- 4.1 Geschlechtsunterschiede der schlafendokrinen Regulation bei jungen, gesunden Probanden.- 4.2 Die klinische Relevanz einer geschlechtsspezifischen schlafendokrinen Regulation.- 4.3 Pathophysiologische UEberlegungen zur Geschlechts-spezifitat der schlafendokrinen Regulation bei Patienten mit Major Depression.- 4.31 Die Rolle der HPA Achse.- 4.32 Die Rolle des Serotonin-Systems.- 4.33 Die Rolle des Immunsystems.- 4.4 Pathomechanismen und Relevanz einer verminderten'delta sleep ratio'bei Patienten mit Major Depression.- 4.41 Vulnerabilitatsmarker fir depressive Stoerungen: eine verminderte 'delta sleep ratio'.- 4.5 Zusammenfassende Schlussfolgerung.

Providing optimal care to patients is a primary concern in the healthcare field. By utilizing the latest resources and research in biomedical applications, the needs and expectations of patients can be successfully exceeded. Novel Approaches for Drug Delivery is an authoritative reference source for the latest scholarly research on emerging developments within the pharmaceutical industry, examining the current state and future directions of drug delivery systems. Highlighting therapeutic applications, predictive toxicology, and risk assessment perspectives, this book is ideally designed for medical practitioners, pharmacists, graduate-level students, scientists, and researchers.

Retrain your thinking and your life with these simple, scientifically proven techniques! Cognitive behavioural therapy, or CBT for short, is often cited as the gold standard of psychotherapy. Its techniques allow you to identify the negative thought processes that hold you back and exchange them for new, productive ones that can change your life. CBT's popularity continues to grow, and more individuals are turning to CBT as a way to help develop a healthier, more productive outlook on life. Cognitive Behavioural Therapy For Dummies shows you how you can easily incorporate the techniques of CBT into your day-to-day life and produce tangible results. You'll learn how to take your negative thoughts to boot camp and retrain them, establishing new habits that tackle your toxic thoughts and retool your awareness, allowing you to be free of the weight of past negative thinking biases. Move on: Take a fresh look at your past and maybe even overcome it Mellow out: Relax yourself through techniques that reduce anger and stress Lighten up: Read practical advice on healthy attitudes for living and ways to nourish optimism Look again: Discover how to overcome low self-esteem and body image issues Whatever the issue, don't let your negative thoughts have the last say--start developing your new outlook on life today with help from Cognitive Behavioural Therapy For Dummies!

This book digs into the complex archaeology of empathy illuminating controversies, epistemic problems and unanswered questions encapsulated within its cross-disciplinary history. The authors ask how a neutral innate capacity to directly understand the actions and feelings of others becomes charged with emotion and moral values associated with altruism or caregiving. They explore how the discovery of the mirror neuron system and its interpretation as the neurobiological basis of empathy has stimulated such an enormous body of research and how in a number of these studies, the moral values and social attitudes underlying empathy in human perception and action are conceptualized as universal traits. It is argued that in the humanities the historical, cultural and scientific genealogies of empathy and its forerunners, such as Einfuhlung, have been shown to depend on historical preconditions, cultural procedures, and symbolic systems of production. The multiple semantics of empathy and related concepts are discussed in the context of their cultural and historical foundations, raising questions about these cross-disciplinary constellations. This volume will be of interest to scholars of psychology, art history, cultural research, history of science, literary studies, neuroscience, philosophy and psychoanalysis.