Advances in Structure and Activity Relationship of Coumarin Derivatives covers the structural behavior of various coumarin derivatives for various potential pharmaceutical applications. Based on substitution targeted for active sites, the book takes a rational approach for designing new and specific potent drugs, optimizing existing ones, and developing novel reactions. This focused primer describes the chemical structure and activity of coumarin derivatives to explore the effects of different substituents at specific positions, and their properties for effective bioactivity.

This volume brings together the latest basic and clinical research examining the effects and underlying mechanisms of psychedelic drugs. Examples of drugs within this group include LSD, psilocybin, and mescaline. Despite their structural differences, these compounds produce remarkably similar experiences in humans and share a common mechanism of action. Commonalities among the substances in this family are addressed both at the clinical and phenomenological level and at the basic neurobiological mechanism level. To the extent possible, contributions relate the clinical and preclinical findings to one another across species. The volume addresses both the risks associated with the use of these drugs and the potential medical benefits that might be associated with these and related compounds.

In Adulthood, Morality, and the Fully Human, John J. Shea describes an adult, moral, and fully human self in terms of integrity and mutuality. Those who are fully human are caring and just. Violence is the absence of care and justice. Peace-the pinnacle of human development-is their embodiment. Integrity and mutuality together beget care and justice and care and justice together beget peace. Shea shows the practical importance of the fully human self for education, psychotherapy, and spirituality. This book is especially recommended for scholars and those in helping professions.

This volume of Progress in Molecular Biology and Translational Science focuses on the molecular biology of eye disease.

This book can enhance everyone's understanding of how women experience loss and grief, and how they transition to resolution. It is an invaluable resource to women and everyone who supports them-spouses, partners, and family members as well as community and government. Women's grief is often a complex phenomenon-a natural, normal experience, but one that can seriously impact everyone-female or male-at every stage of life. Understanding Loss and Grief for Women: A New Perspective on Their Pain and Healing provides a way to look at how women experience loss through the lens of their socially constructed roles, and in light of the theories and practice of grief therapy and support. The book begins by explaining the social construction of women's traditional, transitional, and modern/postmodern roles, and then addresses the social construction of grief theory and practice in past eras and modern society. Several case studies enable readers to see how social constructs shape women's responses to various causes of grief, such as the death of a spouse or partner, child, marriage (divorce), and career (retirement). The final section of the book examines the health impacts of grief, offers suggestions to ameliorate negative health impacts, and emphasizes how loss and grief for women can be used as opportunities for self-growth. This book serves all members of the general population as well as educators, academics, scientists, and students of disciplines such as psychology, psychotherapy, medicine, sociology, and women's studies. It will enable all women to better understand, deal with, and heal from their loss and grief experience. Male readers will empathize with what their spouses/partners, mothers, grandmothers, siblings, and friends are experiencing in loss and grief and understand how to support healthy transition through grief to resolution. The community at large and care providers will learn how to create a more nurturing and supportive environment for women's grief response. Explicates the socially constructed roles of women, in the past and in modern society, to illustrate what has been considered "appropriate" expression and response to loss and grief for women, and to enable a unique understanding the phenomenal loss experience for women Presents an invaluable framework, as a scaffolding, that allows readers to interrogate their own and others' experiences of loss in a novel, more in-depth way-one that supports improved practice in the helping professions Includes women's real-life stories that tell their truths of the loss experience and how grief worked through them in transitioning to resolution Provides seminal information to professional grief counselors, physicians, nurses, clinical psychologists, and psychiatric social workers, as well as students of psychology, sociology, medicine, public health, and women's studies Allows family members, friends, or partners to better understand what a woman who is experiencing loss and grief is feeling, and instructs how to support healthy transition through grief to resolution

International Review of Research in Developmental Disabilities is an ongoing scholarly look at research into the causes, effects, classification systems, and syndromes of developmental disabilities. Contributors come from wide-ranging perspectives, including genetics, psychology, education, and other health and behavioral sciences.

Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer, the latest volume in the Advances in Pharmacology series, presents not only the function of cytochrome P450 but also its pharmacological roles in inflammation and cancer.

This groundbreaking annual review has provided over three decades of knowledge, insight, and research on topics critical to the field of nursing.

In this issue of Radiologic Clinics, guest editor Dr. Hillary W. Garner brings her considerable expertise to the topic of Imaging of Bone and Soft Tissue Tumors and Mimickers. Top experts provide timely articles on the imaging findings and other relevant clinical information of frequently encountered benign and malignant tumors of bone and soft tissue, in addition to separate reviews on common and potentially confusing tumor mimics. In addition, orthopaedic oncologists have contributed valuable perspectives on how they incorporate imaging information into their patient care plans. Contains 11 relevant, practice-oriented topics including bone tumors: what the oncology team wants to know; bone tumors: imaging features of common and rare benign entities; bone tumors: common mimickers; soft tissue tumors: what the oncology team wants to know; soft tissue tumors: common mimickers; bone and soft tissue tumors: horizons in radiomics and artificial intelligence; and more. Provides in-depth clinical reviews on imaging of bone and soft tissue tumors and mimickers, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Transforming Teen Behavior: Parent-Teen Protocols for Psychosocial Skills Training is a clinician's guide for treating teens exhibiting emotional and behavioral disturbances. Unlike other protocols, the program involves both parents and teens together, is intended for use by varied provider types of differing training and experience, and is modular in nature to allow flexibility of service. This protocol is well-established, standardized, evidence-based, and interdisciplinary. There are 6 modules outlining parent training techniques and 6 parallel and complementary modules outlining psychosocial skills training techniques for teens. The program is unique in its level of parent involvement and the degree to which it is explicit, structured, and standardized. Developed at Children's Hospital Colorado (CHCO), and in use for 8+years, the book summarizes outcome data indicating significant, positive treatment effects.