Tailor-Made Polysaccharides in Drug Delivery provides extensive details on all the vital precepts, basics and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industry for understanding and developing high quality products. The book offers a comprehensive resource to understand the potential of the materials in forming new drug delivery methods. It will be useful to pharmaceutical scientists, chemical engineers, and regulatory scientists and students actively involved in pharmaceutical product and process development of tailored-made polysaccharides in drug delivery applications. The utilization of natural polymeric excipients in numerous healthcare applications demand the replacement of the synthetic polymers with the natural ones due to their biocompatibility, biodegradability, economic extraction and readily availability. The reality behind the rise in importance of these natural materials is that these sources are renewable if grown in a sustainable means and they can tender incessant supply of raw materials. Amongst these natural polymers, polysaccharides are considered as excellent excipients because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of polysaccharides in drug delivery.

Our mind is one of the most extraordinary wonders of mankind! We use it to think critically and creatively, it stores our treasured memories, it helps us make friends and look after our loved ones, and it can transform our impossible dreams into reality.Sometimes we encounter glitches in our life's journey. The brain may not advance as fast as expected. This book delves into both the normal as well as the abnormal functioning of a child's mind. Topics covered include intelligence, creativity, consciousness, memory and normal development. It also gives practical advice on how to manage children's mental health and problems like ADHD, dyslexia, autism and depression.The book is timely because of the recent surge in interest of the human mind during the Covid-19 pandemic where there has been a dramatic worldwide increase in mental problems brought about by isolation, economic slowdown, unemployment, and loss of our loved ones.This book is suitable for everyone who is fascinated by the human mind.

The problem of how to understand and to treat masochism has plagued the vast majority of clinicians. The Clinical Problem of Masochism, edited by Deanna Holtzman, PhD, and Nancy Kulish, PhD, focuses on the common and difficult clinical problems posed by masochistic patients who are spread throughout all diagnostic categories. Foremost psychoanalytic clinicians in the field from various theoretical backgrounds demonstrate their approaches to working clinically with these problems. Each expert provides detailed clinical examples, making their approaches and suggestions come alive. This volume, unique in its varied clinical and practical focus, offers therapists of all theoretical persuasions ideas on how to think about and help individuals suffering from masochistic difficulties.

In this issue of Radiologic Clinics, guest editors Drs. Benjamin M. Yeh and Frank H. Miller bring their considerable expertise to the topic of Hepatobiliary Imaging. Top experts in the field offer comprehensive reviews of every major aspect of hepatobiliary imaging: biliary cancer, trauma, vascular disorders, and benign liver disease. This issue also includes articles on imaging modalities (MR, CT, ultrasound), contrast agents, and "Pearls and Pitfalls." Contains 13 practice-oriented topics including abbreviated MR liver protocols; update on MR contrast agents for liver imaging: what to use and when; biliary imaging interpretation pearls and pitfalls: CT and MRI; update on biliary cancer imaging; atypical liver malignancies and diagnostic pitfalls; and more. Provides in-depth clinical reviews on hepatobiliary imaging, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Magnetic Resonance Imaging Clinics, guest editors Drs. John Conklin and Michael Lev bring their considerable expertise to the topic of MR in the Emergency Room. Top experts in the field cover key topics such as penile and scrotal trauma, thoracic emergencies, biliary obstruction, GI/GU emergencies, abdominal and pelvic emergencies in the pregnant patient, pediatric emergencies, and more. Contains 14 relevant, practice-oriented topics including acute stroke; intracranial trauma, hemorrhage, and other non-stroke vascular emergencies; spinal emergencies; head and neck emergencies; musculoskeletal trauma and infection; and more. Provides in-depth clinical reviews on MR in the emergency room, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This clear, concise manual fills the growing need for a text covering the process of physical examination of the spine and extremities. Serving students and clinicians as a functional guidebook, this text incorporates three important features: a tight consistent organization, an abundance of constructive illustrations, and an effective teaching method.

Microbial Resources: From Functional Existence in Nature to Applications provides an exciting interdisciplinary journey through the rapidly developing field of microbial resources, including relationships to aspects of microbiology. Covers the functional existence of microorganisms in nature, as well as the transfer of this knowledge for industrial and other applications. Examines the economic perspective of revealing the potential value of microbial material and figuring it into socio-economic value; legal perspectives; and how to organize a fair allotment of socio-economic benefits to all stakeholders who have effectively contributed to the preservation, study, and exploitation of microbiological material.

Progress in Medicinal Chemistry, Volume 56 provides a review of eclectic developments in medicinal chemistry. This volume includes chapters covering recent advances in cancer therapeutics, fluorine in medicinal chemistry, a perspective on the next generation of antibacterial agents derived by manipulation of natural products, a potential new era for Chagas Disease drug discovery, and imaging in drug development. Specific chapters cover timely topics, such as the development of LRRK2 inhibitors for the treatment of Parkinson's, and recent discoveries and developments in TRPA1 modulators. Users will find a comprehensive resource on the topic of medicinal chemistry that also discusses avenues for the acceleration of drug discovery programs.

Adverse Effects of Engineered Nanomaterials: Exposure, Toxicology, and Impact on Human Health, Second Edition, provides a systematic evaluation of representative engineered nanomaterials (ENM) of high volume production and their high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies, and the general public need to know about nanosafety. Written by leading international experts in nanotoxicology and nanomedicine, this book gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers, and patients. All chapters have been updated with new sections on the endocrine system and other organ systems. In addition, other newly added sections include introductory chapters on the physio-chemical characterization of nanomaterials and interactions between nanomaterials and biological systems, as well as a new chapter that explores risk assessment and management of nanomaterials. This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, also detailing the clinical and pathological consequences of such exposure in the human population.

Nutritional Modulators of Pain in the Aging Population provides an overview on the role of foods, dietary supplements, obesity, and nutrients in the prevention and amelioration of pain in various diseases in the aging population. Headaches, fibromyalgia, joint pain, arthritis pain, back pain, and stomach pain are discussed. In addition, the potential health risks of using foods to reduce symptoms is evaluated. Each chapter reviews pain causing conditions before reviewing the role of food or exercise. Both researchers and physicians will learn about dietary approaches that may benefit or harm people with various types of pain. Chapters include current research on the actions of nutrients in pain treatment, the effects of lifestyle and exercise on pain management, and discussions of dietary supplements that provide pain relief from chronic conditions like arthritis.

Medicinal Spices and Vegetables from Africa: Therapeutic Potential against Metabolic, Inflammatory, Infectious and Systemic Diseases provides a detailed look at medicinal spices and vegetables that have proven safe-and-effective for consumption and the treatment of diseases, including infectious diseases, cardiovascular disease, and cancer. It provides pharmacological evidence, such as the latest information related to efficacy and safety data, in vitro and in vivo studies, clinical trials, and more, to illustrate the use of these spices and vegetables as both palliative and alternative treatments with the goal of furthering research in this area to produce safer and more effective drugs.

Critical Care Neurology, Part I: Neurocritical Care focuses on the care specialists and general neurologists that consult in the ICU and their work with patients in acute, life-threatening situations who are dealing with neurologic or neurosurgical crises emanating from either a preexisting neurologic syndrome or from a new neurologic complication appearing as a result of another medical or surgical critical illness. These two separate clinical situations form the pillars of neurocritical care, hence these practices are addressed via two separate, but closely related, HCN volumes. Chapters in both focus on pathophysiology and management, and are tailored for both general neurologists and active neurocritical specialists, with a specific focus on management over diagnostics. Part I addresses the principles of neurocritical care and the management of various neurologic diseases. Part II addresses the interplay between neurologic complications and the surgical, medical, cardiac, and trauma of critical illnesses that most typically present in the ICU.