Inhalation aerosols continue to be the basis for successful lung therapy for several diseases, with therapeutic strategies and the range of technology significantly evolving in recent years. In response, this third edition takes a new approach to reflect the close integration of technology with its application. After briefly presenting the general considerations that apply to aerosol inhalation, the central section of the book uses the focus on disease and therapeutic agents to illustrate the application of specific technologies. The final integrated strategies section draws the major points from the applications for disease targets and drug products.

Cost-effectiveness analysis is becoming an increasingly important tool for decision making in the health systems. Cost-Effectiveness of Medical Treatments formulates the cost-effectiveness analysis as a statistical decision problem, identifies the sources of uncertainty of the problem, and gives an overview of the frequentist and Bayesian statistical approaches for decision making. Basic notions on decision theory such as space of decisions, space of nature, utility function of a decision and optimal decisions, are explained in detail using easy to read mathematics. Features Focuses on cost-effectiveness analysis as a statistical decision problem and applies the well-established optimal statistical decision methodology. Discusses utility functions for cost-effectiveness analysis. Enlarges the class of models typically used in cost-effectiveness analysis with the incorporation of linear models to account for covariates of the patients. This permits the formulation of the group (or subgroup) theory. Provides Bayesian procedures to account for model uncertainty in variable selection for linear models and in clustering for models for heterogeneous data. Model uncertainty in cost-effectiveness analysis has not been considered in the literature. Illustrates examples with real data. In order to facilitate the practical implementation of real datasets, provides the codes in Mathematica for the proposed methodology. The motivation for the book is to make the achievements in cost-effectiveness analysis accessible to health providers, who need to make optimal decisions, to the practitioners and to the students of health sciences. Elias Moreno is Professor of Statistics and Operational Research at the University of Granada, Spain, Corresponding Member of the Royal Academy of Sciences of Spain, and elect member of ISI. Francisco Jose Vazquez-Polo is Professor of Mathematics and Bayesian Methods at the University of Las Palmas de Gran Canaria, and Head of the Department of Quantitative Methods. Miguel Angel Negrin is Senior Lecturer in the Department of Quantitative Methods at the ULPGC. His main research topics are Bayesian methods applied to Health Economics, economic evaluation and cost-effectiveness analysis, meta-analysis and equity in the provision of healthcare services.

This book provides clinicians and researchers with the current state-of-the-art on the pharmacological treatment of aphasia. The focus is on the role of different pharmacological agents to improve aphasia associated with stroke and to attenuate language dissolution in degenerative conditions like Alzheimer's disease and primary progressive aphasia. This book is the first one that addresses these topics. Leaders in the field provide tutorial reviews on how focal brain injury and degeneration impact on the normal the activity of different neurotransmitter systems and how drugs combined or not with rehabilitation can improve language and communication deficits. This is nicely illustrated by studies on single cases and case series describing the beneficial effects of interventions combining drugs with evidence-based rehabilitation techniques. Throughout the volume, future directions to refine testing aimed to detect gains in language and non-language cognitive deficits promoted by drug treatment are highlighted. This book is essential reading for anyone interested in the rehabilitation of aphasia and related cognitive disorders. This book was originally published as a special issue of Aphasiology.

This book aims at presenting biologists and clinicians with a compact description of the physiological manifestations of sleep that are significant from the viewpoint of the principle of homeostasis. In the jargon of the physiological literature, the word "homeostasis", introduced by W.B. Cannon (1926), refers to the existence of a constant state of extracellular body fluids with regard to their physical and chemical properties. Since normal cell function depends on the constancy of such fluids, in multicellular animals there are many regulatory mechanisms under the control of the central nervous system that act to maintain the constancy of the internal environment.The experimental study of homeostasis in wakefulness already revealed the nature and complexity of the underlying physiological mechanisms. Many of these regulatory mechanisms trigger compensatory changes according to the principle of negative feedback. In contrast, the control of homeostasis across sleep states is still an issue under debate concerning its physiological persistence and significance. The author's aim is to find the specific mechanistic proofs of the actual consistency or inconsistency of the principle in different states of sleep. In this respect, there are several interacting physiological functions that ought to be examined across the sleep states. The selection of the most significant experimental data is carried out with a view to present a simple but not simplistic approach to the issue.The book brings forth the evidence that the systemic homeostatic regulation of many physiological variables underlying cellular life is not active in a particular state of the ultradian sleep cycle in mammals. It also shows the theoretical and functional importance of the principle of homeostasis, as a criterion of the systemic characterisation of the integrative control of physiological functions by the central nervous system during sleep in mammals.

* This is the first book in 30 years to focus specifically on Global Aphasia. it provides: an overview of current evidence base for speech and language therapy in global aphasia. * assessment and therapy ideas specifically tailored to this population including new non-linguistic approaches. * Provides clinical approaches for managing the cognitive difficulties that often co-occur in this population * New ways of assessing functional communication through observation in this hard-to-assess population

This proposed book draws on the expertise of 35 experts in the field of Addiction Medicine to provide the reader with a current and comprehensive view of addiction as related to women, pregnancy, newborns, infants and children. The volume begins by placing current attitudes towards addicted women in a historical context, and continues with contributions on the relationship of gender to substance abuse research, addiction as a general health issue in women, and ethical dilemmas faced when approaching drug use during pregnancy. The volume discusses high-risk pregnancies and HIV infection related to maternal drug abuse. It details specific pharmacotherapy such as methadone and buprenorphine, and assesses society's punitive view toward illicit drug using women. Finally, the book describes outcomes of newborns, infants and children born following intrauterine drug exposure. Health providers in many related disciplines, specialists in Addiction Medicine, social workers and ethicists are among those who will gain insight into the complex interdisciplinary matrix of abuse in women, its unique relationship to pregnancy, and its impact on drug-exposed children. This book was published as a special issue in the Journal of Addictive Diseases.

Why do many people with disorders of communication experience a sense of demoralization? Do these subjective experiences have any bearing on how such problems should be treated? How can professionals dealing with speech, language, hearing and other communication disorders analyse and respond to the subjective and relational needs of clients with such problems? In this book, authors in the fields of communication disorders analyse the psychological, social and linguistic processes and interactions that underpin clinical practice, from both client and clinician perspectives. The chapters demonstrate how it is possible to analyze and understand client-clinician discourse using qualitative research, and describe various challenges to establishing relationships such as cultural, gender and age differences. The authors go on to describe self-care processes, the therapeutic use of the self, and various psychological factors that could be important for developing therapeutic relationships. Also covered are the rarely considered topics of spirituality and transpersonal issues, which may at times be relevant to clinicians working with clients who have debilitating, degenerative and terminal illnesses associated with certain communication disorders. While this book is geared toward the needs of practicing and training speech, language and hearing clinicians, other professional such as teachers of the deaf, psychotherapists, nurses, and occupational therapists will find the ideas relevant, interesting and easily translatable for use in their own clinical practice.

This highly practical resource has been designed to support working memory and curriculum success in the Key Stage 1 and Key Stage 2 classroom. Working memory is crucial for success in maths, reading, reading comprehension and problem solving, yet children with poor working memory often struggle to meet the demands of everyday classroom activities. Filled with activities and support for Key Stage 1 and Key Stage 2 Maths and English, this book offers ideas for the practising teacher on how to make the classroom a place to reinforce memory skills, and to ensure that those with working memory difficulties are included and supported. Key features include: * Information on recognising working memory difficulties * Practical and specific strategies to support learners in the classroom * Graduated activities for Maths and English learners based on the national curriculum The importance of working memory on curriculum success is becoming increasingly evident, with growing emphasis on testing and an ever more demanding curriculum. With photocopiable and downloadable resources, this is an essential book for teachers, teaching assistants and other education staff looking to support working memory with children.

Now in a fully revised and updated third edition, Working with Voice Disorders offers practical insight and direction into all aspects of voice disorders, from assessment and diagnosis to intervention and case management. Using evidence-based material, it provides clinicians with pragmatic, accessible support, facilitating and informing decision-making along the clinical journey, from referral to discharge. Key features of this resource include: A wealth of new, up-to-date practical and theoretical information, covering topics such as the prevention, assessment, intervention and treatment of a wide spectrum of voice disorders. A multi-dimensional structure, allowing the clinician to consider both specific aspects of patient management and aspects such as clinical effectiveness, clinical efficiencies and service management. Photocopiable clinical resources, from an at-a-glance summary of voice disorders to treatment and assessment protocols, and practical exercises and advice sheets for patients. Sample programmes for voice information groups and teacher workshops. Checklists for patients on topics such as the environmental and acoustic challenges of the workplace. Self-assessed personalised voice review sheets and weekly voice diaries encourage patients to monitor their voice quality and utilise strategies to prevent vocal misuse. Combining the successful format of mixing theory and practice, this edition offers a patient-centred approach to voice disorders in a fully accessible and easy-to-read format and addresses the challenges of service provision in a changing world. This is an essential resource for speech and language therapists of varying levels of experience, from student to specialist.

* Psychoanalytic/psychodynamic self-psychology is illustrated using 12 case studies, each of which exemplifies specific theoretical, clinical, and technical principles of the approach. Together, the 12 case studies form a cohesive whole which enables the reader to follow in detail an entire process of therapy, illustrating the technique and its roots in self-psychology theory. * Provides the evidence basis for the efficacy of this treatment of eating disorders and the empirical capability of the theory to predict the development of eating disorders as well as remission from EDs. * The cases and the empirical studies are integrated around the basic themes of the theory so as to create a comprehensive text while balancing between theory, clinical examples, and empirical basis.

Currently a great deal of public discourse around health is on the assumed relationship between childhood inactivity, young people's diets, and a putative steep rise in obesity. Children and young people are increasingly being identified as a population at 'risk' in relation to these health concerns. Such concerns are driving what might be described as new 'health imperatives' which prescribe the choices young people should make around lifestyle: physical activity, body regulation, dietary habits, and sedentary behaviour. These health imperatives are a powerful force driving major policy initiatives on health and education in a number of countries in the Western world. Schools in particular have been targeted for the implementation of a plethora of initiatives designed to help children and young people lose weight, become more active and change their eating patterns inside and outside school. Addressing these issues requires an innovative theoretical approach. Neither the fields of 'eating disorders' nor 'obesity research' has addressed these issues from a sociological and pedagogical perspective. The contributors to this edited collection draw on a range of social theories, including Michel Foucault and Basil Bernstein to interpret the data collected across three countries (Australia and New Zealand, United Kingdom) and from a range of primary and secondary schools. Each chapter addresses various aspects of the relationship between health imperatives as constituted in government policies, school programs and practices, their recontextualised in school practices and the impact of this on the subjectivities of children and teachers. This book was originally published as a special issue of Discourse: Studies in the Cultural Politics of Education.

"Co-authored by a neurologist, a psychiatrist, and a pulmonologist, Sleep Medicine in Clinical Practice reflects the cross-disciplinary nature in the clinical management of sleep disorders. The authors present an overview of sleep medicine including the physiological basis of sleep, diagnostic tools and possible therapeutic strategies, emphasizing throughout the role of the clinician in diagnosing and managing disease. A practical reference for the busy physician, Sleep Medicine in Clinical Practice includes chapters on the assessment and diagnosis of sleep disorders, conditions such as narcolepsy and sleep apnea, the management of insomnia and a selection on co-existent neurologic conditions such as epilepsy and dementia. It will be of interest to sleep medicine specialists and trainees as well as neurologists, pulmonologists, psychiatrists and internists"--Provided by publisher.

This year 's special issue contains papers presented at the 39th Clinical Aphasiology Conference held in Keystone, Colorado in May, 2009. The issue contains another excellent mix of articles, demonstrating the depth and breadth of issues covered in clinical aphasiology at the present time. As a venue for the discussion of applied research in aphasia, CAC encourages researchers to explore the ultimate social ramifications of different assessment and treatment protocols, while retaining strong theoretical underpinnings related to both neurological and cognitive factors involved in the impairment.

This practical, interactive resource is designed to be used by professionals who work with children and young people who have Social, Emotional and Mental Health needs and Speech, Language and Communication needs. Gaps in language and emotional skills can have a negative impact on behaviour as well as mental health and self-esteem. The Language for Behaviour and Emotions approach provides a systematic approach to developing these skills so that young people can understand and work through social interaction difficulties. Key features include: A focus on specific skills that are linked to behaviour, such as understanding meaning, verbal reasoning and emotional literacy skills. A framework for assessment, as well as a range of downloadable activities, worksheets and resources for supporting students. Sixty illustrated scenarios that can be used flexibly with a wide range of ages and abilities to promote language skills, emotional skills and self-awareness. This invaluable resource is suitable for use with young people with a range of abilities in one to one, small group or whole class settings. It is particularly applicable to children and young people who are aiming to develop wider language, social and emotional skills including those with Developmental Language Disorder and Autism Spectrum Disorder.

The first source on insomnia treatment since the advancement of newer drug options and cognitive behavioral therapies, "Insomnia: Diagnosis and Treatment" presents a comprehensive reference on the complications, evaluation, and treatment of insomnia. Ideal for sleep medicine specialists, psychiatrists, and neurologists, this text uses a multi-disciplinary approach to discuss the essential information on assessment and treatment, while also covering the science of insomnia, including the definitions, origins, and complications of the condition.

Key features include:

* The field of AAC is a rapidly expanding one, as both technology innovations and demographic profiles make it increasingly possible and important to provide non-speech communication options for individuals with significant communication impairments. * Case reports provide a hook for student learning, drawing their interest and providing immediate relevance for students. * Features internationally recognised authors who are experts in their field and have been drawn from Ireland, the United Kingdom, the USA and Australia, to ensure that the reach of the text is broad and internationally relevant.

This is a text for practicing pharmacists on the understanding, management and treatment of Obesity. Obesity is an important risk factor for a number of chronic conditions such as heart disease, stroke, some cancers and type two diabetes. It is responsible for more than 9000 premature deaths a year in England alone and is a growing problem both among adults and children especially in the UK and USA. Community pharmacists now have an increasingly important role in public health. The increased health promotion responsibility under the new contract in the UK and improved consultation facilities now available means that a book such as this is very timely. This text focuses on pharmacists care with the first part concentrating on the background and epidemiology of the problem, the current rates of obesity and the facts, also linking obesity with the emergence of potential public health crisis. Part two of the text focuses on the prevention of obesity including prevention on government level, psychological intervention and exercise and nutrition. The chapters then go on to include the pharmacological interventions including drugs available and also surgical interventions and diets. The closing chapter looks at the structure of the evolving services from community pharmacy nationally and internationally.

This practical introduction to linguistics is a must-have resource for all speech and language therapy students, providing you with the fundamental theory needed as a foundation for practice. Written by authors with extensive experience in both research and teaching, Introductory Linguistics for Speech and Language Practice equips you with a practical understanding of relevant linguistic concepts in the key language areas of morphology, syntax, semantics, discourse and pragmatics. Each chapter opens by explaining why the information is of relevance to the speech language therapist, and this integrated approach is emphasised via reference to relevant clinical resources. Exercises throughout each chapter also allow you to test your understanding of key principles and apply this knowledge to other areas of your study. This concise, readable guide is a core text for all undergraduate and postgraduate students of speech and language therapy, and is also ideal for qualified therapists wanting to enrich their understanding of the linguistic assessments they use in practice.

Eating disorders (EDs) have become a social epidemic in the developed world. This book addresses the close links between EDs and exercise, helping us to understand why people with EDs often exercise to excessive and potentially harmful levels. This is also the first book to examine this issue from an ethical and legal perspective, identifying the rights and responsibilities of people with EDs, heir families and the fitness professionals and clinicians that work with them.

The book offers an accessible account of EDs and closely examines the concept of addiction. Drawing on a wide range of medical, psychological, physiological, ociological and philosophical sources, the book examines the benefits and risks of exercise for the ED population, explores the links between EDs and other abuses of the body in the sports environment and addresses the issue of athletes with disordered eating behaviour. Importantly, the book also surveys current legislation and professional codes of conduct that guide the work of fitness professionals and clinicians in this area and presents a clear and thorough set of case histories and action points to help professionals better understand, and care for, their clients with EDs.

Exercise and Eating Disorders is important reading for students of applied ethics, medical ethics and the ethics of sport, as well as for fitness professionals, psychiatrists, clinical psychologists, sports coaches and sport and exercise scientists looking to improve their understanding of this important issue.

This practical teaching resource has been designed to give children aged 9-12 the basic tools required to challenge some of the conflicting information which they may encounter in everyday life. With increasing exposure to modern information technology and social media, amongst other things, children are increasingly exposed to misleading information that can seriously influence their worldview and self-esteem. The sooner they are helped to approach some of this material with a critical eye, the better they will be able to make independent judgements and resist undue persuasion. Key features of this book include: * Short texts designed to give opportunities for critical examination, created to be points of discussion with individuals, groups or whole classes * Topics covering seven areas of critical thought, ordered in level of difficulty, including finding contradictions, and detecting bias and fake news * Supporting teacher prompts and questions, as well as photocopiable resources without prompts The ability to question and evaluate information is an essential life skill, as well as a key skill for academic learning, yet it remains one of the most challenging aspects of comprehension to teach. This is a vital text for teachers, teaching assistants and other professionals looking to develop critical thinking skills in their students.

The second edition of Making Mandated Addiction Treatment Work integrates cutting edge research with evidence-based addiction treatments to create a unified and effective treatment model for mental health professionals and those in training. Because the largest and fastest growing segment of the community-based addiction treatment population includes those who are mandated, Barbara C. Wallace provides insightful best practices for tailoring addiction treatment to diverse and challenging clients, including those who may have a history of trauma or mental disorders, different levels of motivation, and a high risk of relapse. Applicable in a variety of treatment settings in both urban and rural communities, this text weaves together new research and vivid case studies into a concise and practical resource. This book is ideal for practitioners and students of public health, criminal justice, and social welfare services.

This is the basic text of the Narcotics Anonymous fellowship. Just as with alcoholism, there is no 'cure' for narcotic addiction, but recovery is possible through a program adapted from the ""Twelve Steps and Twelve Traditions"" of Alcoholics Anonymous. This book, written by addicts, for addicts, about addicts, sets forth the spiritual principles of Narcotics Anonymous that hundreds of thousands of addicts have used in recovery. Intended as a complete textbook for every addict seeking recovery, ""Narcotics Anonymous"" describes the N.A. program and how it works. It includes the ""N.A. Twelve Steps and Twelve Traditions"", as well as many personal stories of men and women who have found freedom from addiction through Narcotics Anonymous.

Many national professional organizations of speech-language pathologists have adopted evidence-based practice (EBP) as the preferred approach to clinical practice. This mandate brings with it an added responsibility for university programs because they need to prepare future generations of speech-language pathologists for these new demands.

This special issue is the first in a peer-reviewed journal in the field that focuses on the teaching of EBP at the pre-professional level! That is, four university programs from three continents (Australia, Europe, and North America) showcase how they conceptualized and implemented their innovative approach to teaching EBP.

Because many programs are in the midst of moving toward EBP, this is a must read for anyone who is teaching or learning in a university-based program in speech-language pathology.

We believe that this issue will serve as a catalyst for increased scholarly discourse on this critical need.

First published in 2012. Routledge is an imprint of Taylor and Francis, an informa company.

Fourteen specialists from across the European Union discuss current issues regarding Middle Eastern and North African immigrants in Europe, focusing on topics such as immigration legislation, assimilation, integration, multiculturalism, community formation, citizenship, political participation, and religious and cultural identities.
This book was previously published as a special issue of the journal Immigrants and Minorities.