In this issue of Surgical Clinics, guest editor Dr. John M. Kane brings his considerable expertise to the topic of A Surgeon's Guide to Sarcomas and Other Soft Tissue Tumors. In 2021, more than 13,400 new soft tissue sarcomas will be diagnosed. This issue provides a timely update for management of the most common sarcomas, including discussions of pathology, imaging, chemotherapy, radiation, and reconstruction. Contains 13 relevant, practice-oriented topics including the implications of an unplanned sarcoma excision (the "Whoops" operation); the importance of preoperative pathology and the optimal biopsy of soft tissue masses; gastrointestinal stromal tumors (GIST) and the general surgeon; the evolving management of desmoid/aggressive fibromatosis; plastic surgery reconstruction of sarcoma resection defects; and more. Provides in-depth clinical reviews on sarcomas and other soft tissue tumors, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Surgical Oncology Clinics, guest editor Dr. Traci L. Hedrick brings her considerable expertise to the topic of Colorectal Cancer. Excluding skin cancers, colorectal cancer remains the third most common cancer diagnosed in both men and women in the United States. In this issue, top experts in the field provide current discussions on surgery of rectal cancer, colon cancer, targeted therapies, technological advances, genetics of colorectal cancer, and health disparities. Contains 12 relevant, practice-oriented topics including preoperative staging and evaluation of colorectal cancer; technological advances in the surgical treatment of colorectal cancer; surgical principles of rectal cancer; targeted therapy for colorectal cancer; surgical principles of colon cancer; molecular genetics of colorectal cancer/hereditary colorectal cancer syndromes; and more. Provides in-depth clinical reviews on colorectal cancer, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This book aims to facilitate readers to understand the origin, growth pattern and relationship between tumor and adherent structure of craniopharyngioma, so as to improve the cure rate and safety of surgery. It's contributed by Neurosurgery Department of Nanfang Hospital, Southern Medical University, China, which focuses on the management of craniopharyngioma. This book covers histoembryology of craniopharyngioma, together with anatomical morphology and abundant clinical data, systematically showing an innovative classification method, i.e. QST classification. This classification method can better reflect the different origin and growth pattern of craniopharyngioma,the relationship between tumors and surrounding structure of the tumor growth pattern, and clinical significance in surgery. The 70 clinical cases with different classification and treatment history are discussed as an important reference for surgical treatment of craniopharyngioma. The anatomy, morphology and pathology of sellar region also have great reference value for researchers in the field of neural science. The underlying intention of this book is to help bring a change in the concept that "craniopharyngioma is an incurable benign tumor only due to its anatomical location".

In this issue of Surgical Oncology Clinics, guest editor Oluwadamilola "Lola" Fayanju brings considerable expertise to the topic of Disparities and Determinants of Health in Surgical Oncology. Provides in-depth, clinical reviews on the latest updates on Disparities and Determinants of Health in Surgical Oncology, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize

In the past, liver resections and liver transplantations were performed by different surgical teams, with very little interplay between the two. However, the evolution toward more complex operations called for an increasingly intense interaction between these surgical techniques: split liver and living donor liver transplantation have become popular in the transplant community, utilizing the Coinaud segmental anatomy in a very sophisticated way, while portal and arterial resection and reconstruction have become indispensable methods for treating Klatskin tumors infiltrating the hepatic hilum. This book offers a complete overview of the connections between liver transplantation and hepatobiliary surgery. It focuses on ex situ techniques for resection of tumors at the suprahepatic confluence, with or without venous reconstruction, and on total vascular exclusion of the liver with the aid of a venovenous bypass that should be a surgical option for referral centers in hepatopancreatobiliary surgery. By taking into consideration the development of minimally invasive liver surgery, it will introduce readers to a variety of new perspectives such as: vascular exclusion techniques with or without extracorporeal circulation, hemodynamic implications and lessons learned from liver transplant surgery, and technical details on pediatric transplantation and its informative role in modern biliary tract surgery.

Despite the rising popularity of the minimally invasive laparoscopic option, open nephron-sparing surgery is still seen by many experts as the 'gold standard' for open surgery for kidney tumors and should remain the first choice for many patients. This challenges the idea that less-invasive therapies are always more desirable than open surgery. While laparoscopic nephron-sparing surgery may be a more attractive option for treating small, easily accessible kidney tumors, for large tumors this is not always the case. Nephron-sparing surgery is a outstanding text that analyses all forms of surgery, open or laparoscopic, as well as providing a backdrop on renal cell carcinoma in general, and the complications and outcomes following surgery that both surgeon and patient will face. Featuring 100 colour photos, the text includes chapters on: Imaging renal masses: current status Open nephron-sparing surgery for renal cell carcinoma Minimally invasive approaches for renal cell carcinoma: an overview Laparoscopic partial nephrectomy Controversies in nephron-sparing surgery Renal cell carcinoma: long-term outcome following nephron-sparing surgery Dr Sasidharan and Professor Soloway have created a superb text covering all aspects of nephron-sparing surgery that should provide excellent guidance for all those who are just beginning to perform nephron-sparing surgery or act as an aide-memoire for those familiar with nephron-sparing surgery.

In this issue of Thoracic Surgery Clinics, guest editor Farid Shamji brings considerable expertise to the topic of Lung Cancer. Provides in-depth, clinical reviews on Lung Cancer, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

This issue of Surgical Oncology Clinics, guest edited by Dr. Roshni Dasgupta, is devoted to Pediatric Cancer. Dr. Dasgupta has assembled expert authors to review the following topics: Management of Neuroendocrine Cancer and GIST in Pediatric Patients; Management of Thyroid Tumors in Pediatric Patients; Management of Liver Tumors in Pediatric Patients; Management of Renal Tumors in Pediatric Patients; Management of Rhabdomyosarcoma in Pediatric Patients; Management of non-Rhabdomyosarcoma Soft Tissues Tumors in Pediatric Patients; Management of Melanoma and Skin Cancer in Pediatric Patients; Management of Lung Metastases in Pediatric Patients; Management of Adrenal Tumors in Pediatric Patients; Minimally Invasive Surgery and New Techniques in Pediatric Cancer Patients; Fertility Considerations and the Pediatric Cancer Patient; Management of Neuroblastoma in Pediatric Patients; Management of Germ Cell Tumors in Pediatric Patients; and more!

Intended for medical oncologists, surgeons, obstetricians, gynecologists, geneticists, genetic counselors, and primary care physicians, this text presents the epidemiological, biological, and clinical issues associated with hereditary breast cancer. It offers clear guidance on the application and utilization of cancer risk assessment models, genetic counseling and testing of high risk patients, and screening and prevention options for individuals at risk of hereditary breast cancer. Addressing every essential aspect of hereditary breast cancer, this source offers comprehensive analyses of hereditary breast cancer-associated syndromes, low penetrance genes, and hereditary breast cancer associated with mutations in the BRCA1 and BRCA2 genes.

This highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease. It starts off by presenting the molecular mechanisms, genetic testing and counseling, and variants of unknown significance (VUS) to help readers understand the contemporary interpretation of the disease. Further chapters focus on the surveillance, diagnosis and treatment, including chemoprevention, risk reduction and drug development based on molecular mechanisms. It also includes a chapter on the latest findings from the HBOC database, ethical issues and the parp inhibitors, and discusses innovative thinking to manage and understand the disease. Hereditary Breast and Ovarian Cancer - Molecular Mechanism and Clinical Practice offers breast surgeons, medical oncologists, gynecological oncologists and genetic counselors a comprehensive overview of the disease. Providing insights into recent scientific findings and further avenues for investigation, it is also a thought-provoking and informative read for researchers and scholars.

The book offers a comprehensive review of the relations between volumes and outcomes in oncological surgery especially in Italian hospitals, based on national and regional data. After illustrating the quality-control methodology and the determinants of surgical outcomes, it discusses the volume-outcome relationship in different fields of surgical oncology (cancers of the upper and lower gastrointestinal tract, hepatopancreatobiliary system, breast, sarcomas etc.) and suggests possible solutions. The latest findings from Europe and the USA are also presented.

This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Douglas L. Fraker, is devoted to Endocrine Tumors. Dr. Fraker has assembled expert authors to review the following topics: Management of thyroid nodular disease: Current cytopathology classifications and genetic testing; Surgical management of lymph node compartments in papillary thyroid cancer; Current guidelines for post-operative treatment and follow-up of well differentiated thyroid cancer; Outpatient thyroid surgery - is it safe?; Asymptomatic hyperparathyroidism- diagnostic pitfalls and surgical intervention; Intra-operative PTH monitoring: optimal utilization; Minimally invasive parathyroidectomy vs bilateral neck exploration for primary hyperparathyroidism; Pheochromocytoma and paraganglioma: Diagnosis, genetics, and treatment; Minimally invasive adrenalectomy; Treatment of adrenocortical cancinoma: benefits of aggressive surgery; Biochemical diagnosis and pre-operative imaging of gastro-intestinal neuroendocrine tumors; Minimally invasive techniques for resection of pancreatic neuroendocrine tumors; and Treatment of metastatic neuroendocrine tumors to the liver.

Knowledge of cutaneous lymphomas has been growing significantly as a result of important discoveries in immunology, molecular biology, and immunohistochemistry. Improved clinical pathologic correlation and follow-up data, as well as the synergistic collaboration among different lymphoma registries and specialists from several academic medical centers have greatly contributed to the understanding of the difficult field of cutaneous lymphoproliferative disorders. While these advances have increased understanding of skin lymphomas, they have also produced an extensive and sometimes confusing litany of articles, studies, and classification schemes. This issue on Cutaneous Lymphomas in Surgical Pathology Clinics provides an organized and updated review of this challenging topic by leading experts. It bridges critical knowledge gaps in the diagnosis of cutaneous lymphomas. Sezary Syndrome, Mycosis Fungoides and variants are presented along with B-cell, CD30, lymphoproliferative disorders among others. In addition to multiple clinical and microscopic images, tables and algorithms are presented to aid in diagnosis and staging. Beyond its usefulness to general pathologists, dermatopathologists, and hematopathologists, this information is intended to be helpful for dermatologists, hematologists/oncologists, fellows, and residents.

This volume is the product of the author's long experience with melanomas and sarcomas and to a lesser but significant degree with upper gastrointestinal cancers, colorectal and breast cancers. As such, it offers a "hands-on" practical guide to approaching complex soft-tissue tumors and for performing more extensive tumor resections based on over 40 years of surgical experience. It provides important details about the positioning of patients, incision types, and exposure which can be of paramount importance in the resection of certain tumors. The book contains important general surgical principles for approaching tumors in a variety of locations but also offers the detail necessary for the safe and oncologically sound resection of these malignancies. Moreover, this operative atlas contains specific information for procedures which are not as commonly encountered in surgical training, but can be invaluable in the management of patients with locally aggressive tumors, such as hemipelvectomy and its variants, sacral resections, and forequarter amputation. Through the use of multiple detailed illustrations, Atlas of Operative Procedures in Surgical Oncology serves as a valuable resource to the general surgeon or surgical oncologist in the operative management of patients with cancer in the abdomen, retroperitoneum, pelvis or extremities.

This book comprehensibly describes the clinical details of anatomic hepatic resection using the Glissonean pedicle approach for hepatocellular carcinoma. It includes all aspects of the surgical anatomy of the liver, preoperative management of patients, surgical techniques, and intraoperative key points to prevent postoperative complications. The first three chapters provide a general introduction to the clinical anatomy of the liver, preoperative management of patients with hepatocellular carcinoma, basic techniques for hepatic resection using the Glissonean approach, and the application of dye staining in anatomic hepatic resection. Subsequent chapters present the technical details of anatomical segmentectomy (Couinaud's classification), sectionectomy and hemi-hepatectomy for hepatocellular carcinoma using the modified suprahilar Glissonean approach. All of these hepatectomies can be performed using simple and easily available surgical instruments. In addition, it discusses precise transection of the deepest hepatic parenchyma guided by methylene blue staining. It is a useful and timely reference for hepatobiliary surgeons, clinical staff, and medical students.

This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Frederick Greene, focuses on Surgical Oncology in the Community Cancer Center. An array of experts have come together to explore topics on Sarcoma Management, Minimally Invasive Esophagectomy, Multidisciplinary Clinics and the Surgeon's Role in the Hospital Cancer Program, Breast Cancer Care in the Community Cancer Center, Lumpectomy versus Mastectomy Rates in the Community Setting, American College of Surgeons Oncology Group trials and the Community Surgeon, Quality Surgical Oncology Care in the Community: Training versus Hospital Volume, The Impact of Dedicated Tumor Boards in Clinical Trials, The National Accreditation Program for Breast Centers: Quality Improvement Through Standard Setting, and much more.

A state-of-the-art resource on current and future advances in the treatment of intradural spinal tumors Tumors of the spinal canal provide unique challenges in terms of surgical approaches and oncological treatment. Management requires in-depth knowledge of the intricate anatomical relationships between the tumors and normal spinal pathways, restricted corridors of entry, and limitations of drug penetration. Over the past few decades, significant strides have been made in the treatment of these tumors. Development of minimally invasive techniques and greater understanding of these pathologies has resulted in improved safety, precision, and outcomes. Tumors of the Spinal Canal: Surgical Approaches and Future Therapies by Ankit I. Mehta and esteemed contributors is the most comprehensive textbook written to date on this topic. The book starts with two opening chapters covering an overview and anatomy, followed by three sections and 11 chapters on intramedullary spinal tumors, intradural extramedullary tumors, and peripheral nerve tumors. The comprehensive review encompasses anatomy, pathophysiology, therapeutic and surgical advances, diverse surgical techniques, and future directions. Throughout the text, readers are provided with the necessary tools to master management of these clinically difficult tumors, from both a medical and surgical standpoint. Key Highlights Treatment algorithms, clinical study summaries, and differential diagnoses presented in reader-friendly tables enhance acquisition and retention of knowledge Comprehensive analyses and pearls from masters provide insights on how to manage complications and improve patient outcomes Discussion of current research innovations, clinical trials, and future directions that have the potential to change the treatment paradigm Neurosurgical residents, spine fellows, and complex spine surgeons will benefit from reading this resource, while the intradural spinal tumor treatment paradigms provide an invaluable clinical tool for neurooncologists and oncologists. This book includes complimentary access to a digital copy on https://medone.thieme.com.

The mediastinum is a hollow space within the thoracic cavity that may give rise to a wide spectrum of tumoral conditions from the benign to the intermediate to the highly malignant neoplasms. In addition, other inflammatory and infectious conditions may also arise in this space, which renders the practice of mediastinal pathology, almost a general surgical pathology practice. However, there are numerous mediastinal conditions that are important not only for diagnosis but also for treatment and clinical outcome. Due to the unusual location and because of the complexity of the tumors occurring in the mediastinum, there are only a few experts in this particular anatomic area. In fact, there are no more than 3-4 individuals worldwide with enough experience to properly diagnose, classify, and make treatment suggestions when these tumors arise in the mediastinum. More recent developments in tumor diagnosis and classification have created a vacuum in the general pathologist who often is confronted with this pathology and becomes uneasy about the specifics. For instance, recent developments in tumor pathology have led to the classification and staging of mediastinal tumors in more innovative ways that are in need of proper highlighting. Needless to say, even though there are a few publications on mediastinal pathology, the books are either obsolete or incomplete, in addition of providing superficial knowledge. Unfortunately and with all due respect to the authors of those publications, neither of those books is written by experts in the area. Rather the books were written out of the lack of information in mediastinal pathology. Even the World Health Organization (WHO) publication, which is truly more on lung and pleural neoplasms, has inserted in its contents a portion of mediastinal tumors, such portion not only is superficial and incomplete but also at least highly controversial if not flat out incorrect. . This text's goal is to present comprehensive and up to date information of the diverse pathology that can be encountered in the mediastinal compartment. The book will be divided in 11 different chapters based on the lineage of the diverse tumors that occur in the mediastinum, i.e. epithelial, neuroendocrine, lymphoid, etc (see table of contents). In addition, two separate chapters will be included -one on the radiological aspects and the others on the surgical approach to the different mediastinal tumors., bringing a total of 13 chapters. In the pathology section, the book will include current staging and classification systems of the different tumors. In addition, it will address the most current criteria for diagnosis and the differential diagnosis. Although the emphasis of the book is on diagnostic surgical pathology, every chapter will include the use of immunohistochemical techniques, electron microscopy, and molecular biology when necessary. The book will be extensively illustrated so that the reader will benefit of the different histomorphology of mediastinal tumors. Because of the nature of this specific anatomic area and the need to develop a standard text, Mediastinal Pathology should be of high interest to general surgical pathologists, thoracic pathologists in particular as well as thoracic surgeons, oncologists, and radiologists. Needless to say, this book will be of interest to pathology residents and fellows as well as to those seeking more in depth knowledge of thoracic - mediastinal pathology.

This extraordinary monograph provides the precise neurovascular anatomy involved in open-abdominal radical hysterectomies, information that is essential for surgeons. For the surgical treatment of invasive cervical cancer, E. Wertheim reported the first systematic data on radical hysterectomy in the early 20th century. While Okabayashi's radical hysterectomy technique, which modified Wertheim's approach, later became the mainstream choice for the treatment of Stage Ib and IIb cervical cancer in Japan, the anatomy of the pericervical area is still not fully understood. The recent spread of laparoscopic surgery and robotic surgery also requires a clear grasp of the anatomy of the blood vessels in the connective tissues of the female pelvis. Precise Neurovascular Anatomy for Radical Hysterectomy provides comprehensive information on the surgery and surgical steps necessary for the complete preservation of the nerve function of the urinary bladder and rectal-nerve-sparing radical hysterectomy. All illustrations presented in this book were drawn by the first author - a pioneering gynecological surgeon - and reflect real-world procedures. Plus, a total of 4 hours of supplementary videos introducing the history of hysterectomy, the concept and precise anatomy of nerve-sparing radical hysterectomy, and live surgery provide valuable visual aids for professionals. All anatomical features described are essential and practical, and have been refined based on the latest clinical practice. As such, the book offers a valuable resource for all gynecological surgeons and general surgeons with an interest in gynecological oncology.

The 25th volume of this highly successful series covers a range of interesting topics, including biological therapy in inflammatory bowel disease, recent surgical approaches in rectal cancer, tumor markers in HPB and GI malignancies, bridging therapy for hepatocellular carcinoma, adjuncts to liver resection, IgG-related HPB diseases, ERCP-induced perforations and superior mesenteric artery syndrome. As in the previous volumes, the chapter on advances in GI surgery reviews the important new developments in the field. The GI Surgery Annual 25th Volume provides up-to-date information on current hot topics.

Due to recent advances in laparoscopic gastrectomy for gastric cancer, a high-resolution atlas in this field was felt necessary. This book describes the laparoscopic surgical procedure and precautions of lymph node (LN) dissection, comprehensively. The details of preoperative preparation, regional LN dissection, and digestive tract reconstruction are introduced based on a large numbers of clinical cases. Modified intracorporeal anastomosis procedure and clinical application of indo cyanine green (ICG) in LN dissection are included. This atlas will be of benefit to gastrointestinal surgeons, surgical oncologists, and minimally invasive surgeons.

This book provides a comprehensive overview of contemporary evidence-based management of urothelial carcinoma. The first part of the book is devoted to urothelial carcinoma of the bladder and includes detailed description of the diagnosis and treatment of non-muscle-invasive, muscle-invasive, and advanced or metastatic disease. Attention then turns to upper tract urothelial carcinoma (UTUC), with individual chapters on diagnosis, nephron-sparing surgery, nephroureterectomy, and treatment of advanced or metastatic UTUC. The text is supported by many illustrations, photos, and tables that clarify management, and surgical video clips are also available to readers. The book will be a welcome addition to the literature as progress continues to be made in understanding the exact pathophysiology of urothelial carcinoma and in developing more effective diagnostic and therapeutic modalities. It will be useful both to researchers in the field of urothelial carcinoma and to clinicians, including especially residents and fellows.

Renal Cancer: Current Status and Innovations provides a useful guide to the fundamental basics and latest diagnostic and treatment techniques for Renal Cancer. It features clearly structured and easy-to-understand chapters enabling the reader to develop a thorough understanding of screening, surveillance, diagnostics, pathology, robotic and open surgical approaches, ablation, medical treatment, psychology, and future innovations. The book provides a valuable resource for the full spectrum of clinicians involved in the multidisciplinary management of Renal Cancer.

This work presents a clear approach for the reconstruction of head and neck cancer excision defects. Starting with a brief historical account of head and neck reconstruction, the principles of resection and reconstruction of head and neck cancer, the book then provides a detailed overview of head and neck reconstruction based on head and neck subsites; various reconstruction techniques; best approaches; and the challenges faced in reconstruction and how to overcome them. Lastly, it discusses future directions in head and neck reconstruction.