Breast cancer made Jennie Nash a wise old woman at the age of thirty-six. She learned, among other things, that her instincts are good, her kids are really resilient, and that, in the fight against breast cancer, the journey for patients, family, and friends can be a surprisingly positive, life-changing experience.

Some five years younger than the AMA-recommended age for mammograms, Jennie Nash insisted she be tested, not because of a lump but because of a hunch brought on by a friend's battle with lung cancer. Jennie was as shocked to discover as her friend had been that cancer knows no age limits.

From detection and surgery to reconstruction and recovery, Jennie gives readers a road map for a journey no one chooses to take. She details both the large and small lessons learned along the way: the importance of a child's birthday cake; the pleasure of wearing a beautiful, provocative red dress; how to be grateful rather than guilty when someone brings lasagne to the door; and that sometimes the only difference between getting to live and having to die is luck.

A celebration of survival, Jennie Nash's account transforms one of life's most harrowing experiences into a story of reassurance and enlightenment.

Dr. Bob Arnot, author of the number one bestseller The Breast Cancer Prevention Diet, is back with an exciting new plan to protect men against prostate cancer. This debilitating cancer strikes nearly 180,000 men each year. Many undergo a great deal of pain and suffering and 37,000 die. Even when the cancer is caught early and surgically removed, there can be serious short—and long-term side effects, including incontinence and impotence.

Could it happen to you? New research shows that up to 25 percent of men in their thirties have microscopic, latent prostate cancer. By the time a man enters his fifties, the figure is even higher — 40 percent. In some men, these cancers remain dormant, but in others they can become clinically significant tumors, sometimes at ferocious speed. At present, nothing can prevent these latent cancers from starting, but there is some great good news. Many top researchers believe their transition into active, even life-threatening, tumors may be delayed or even prevented entirely.

As with breast cancer, Dr. Arnot has found that the foods men eat can have a profound influence on whether or not they get clinical prostate cancer. In The Prostate Cancer Protection Plan, he tells us what these wondrous foods are and how we can use them as part of a sensible, fun, and delicious eating program.

Dr. Arnot bases his menus on the incredibly varied, time-tested, and delicious cuisines from other cultures where the incidence of prostate cancer is dramatically less than in the United States. And he provides clear and simple scientific explanations for his choices, so the reader can customize his own plan and still get the right foods with the right nutrients.

With delicious recipes, advice on eating out and on the run, stress-busting techniques, fitness programs, a self-test for assessing your own risk, and other prostate cancer — fighting strategies such as promising new drugs and supplements, The Prostate Cancer Protection Plan offers a safe, effective program that will not only stave off this dread killer, but will help men lose weight, gain energy, and feel more relaxed as well.

This comprehensive, illustrated guide presents representative general surgery, including gastrointestinal tract, hepatobiliary and inguinal hernia. Surgery is generally based on the microanatomy; however, in practice surgery involves more dynamic and floating anatomy. In the last decade, the methods have been constantly improved, shedding new light on classical anatomical science. Laparoscopic is one such methodology. All illustrations presented in this book have been drawn by the author - a pioneering surgeon - and show real-world procedures. All the methods introduced are practical and have been refined based on the precise clinical and embryological anatomy. This unique book offers readers essential insights into efficient and high-integrity surgeries in abdominal region. As such, it is a valuable resource for all gastrointestinal surgeons.

Gastric cancer is the fourth most common cancer in the world. Most gastric cancers are diagnosed in advanced stages, and the prognosis remains poor. The 5-year survival rate is 40-60% in eastern countries and around 25% in the west. Among advanced gastric cancer cases, peritoneal implantation is one of the most common forms of metastasis and around 14% of cases present peritoneal metastases at initial diagnosis, presenting a survival of 3-6 months. Until the early 1990s it was considered a terminal disease. But today these patients have some opportunities to be treated with curative intent or to prolong their life. Although the prognosis remains poor, there are some treatment options including cytoreductive surgery, neoadjuvant therapy, and some forms of intraperitoneal chemotherapy with or without hyperthermia. These are aggressive treatments, so we must be careful when selecting patients. Imaging and preoperative staging are also crucial in selecting patients for appropriate treatment. The surgical technique is described and a detailed demonstration video is available in the e-book version. New forms of treatment such as PIPAC and new scientific advances and future perspectives are discussed. This book is an update on this topic and attempts to provide an overview for all medical personnel involved in the treatment of these patients.

The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.

This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Mark Arnold, is devoted to Colon Cancer. Dr. Arnold has assembled expert authors to review the following topics: Chemotherapy for Colon Cancer; Colon Cancer: What We Eat; Colon Cancer: Inflammatory Associated Cancer; Colon Cancer: The Imaging Conundrum; Minimally Invasive Surgical Approaches to Colon Cancer; Population Screening for Hereditary Colorectal Cancer; The Economics of Colon Cancer; Clinical Trials in Colon Cancer; Advanced Colonoscopic Techniques; Surgical Treatment of Metastatic Disease; The Metastatic Lymph Node; and more!

Breast MRI is no longer the domain of specialised centres; it is now a mainstream diagnostic technique, and an understanding of its applications is essential for any clinician involved with breast imaging. The Handbook of Breast MRI provides core knowledge and clinical guidelines for performing breast MRI in everyday practice. Introductory chapters on breast MRI basics, anatomy and pathology are followed by detailed chapters on the use of MRI in screening, staging, problem-solving and MRI-guided interventions, each containing diagnostic algorithms, tables and lists for quick access to key diagnostic information. Each chapter also contains a selection of self testing questions, and numerous Appendices concisely summarise tumour classification and current breast cancer treatment options. The Handbook of Breast MRI is an invaluable practical diagnostic resource for radiologists, surgeons, oncologists and all clinicians involved in breast cancer management.

This book assembles recent achievements in both basic research and clinical management in the field of hepatology, virology and immunology. It provides up-to-date information for clinicians who can apply the relevant knowledge to their daily clinical practice and for researchers who are interested in clinically orientated studies. The updated and detailed technology, state-of-the-art treatment strategies provided in this book serve as references for clinicians and resident physicians in the daily management of ACLF. The rationality and strategies for basic research as well as patient management in this book can also be a valuable reference for other fatal and end stage liver diseases than HBV induced ACLF. This volume 1 has 6 chapters and focuses on the definition, research technology, virology, genetics, and immunology.

This book focuses on Barrett's Esophagus (BE), a clinical condition that must be evaluated in all patients affected by chronic GERD, and with an important link to esophageal cancer. Divided into four sections (morphological background, epidemiology and natural history, diagnosis, and treatments), this handy volume provides the latest indications regarding endoscopic approaches (first level and advanced endoscopy), pathological studies (pathology and molecular biology), and state-of-the-art therapeutic options (medical, endoscopic, and surgical) for BE. As such, it offers a valuable reference guide for all professionals involved in the management of BE (gastroenterologists, endoscopists, pathologists and surgeons), offering them a comprehensive overview and deeper understanding of this seemingly superficial disease.

The widespread acceptance among the oncology community at large of cytoreductive surgery and HIPEC as a potentially curative treatment for peritoneal metastases has paved the way for innovative new therapies that could benefit a larger proportion of patients. Much has been and continues to be published on this subject. This book provides comprehensive reviews on the various aspects of managing peritoneal metastases. The authors highlight essential practical issues that surgical oncologists encounter in their day-to-day practice, and try to before provide evidence based answers to address them. All chapters were written and/or reviewed by leading experts in this field.

The treatment of skin cancer has become an increasingly multispecialty practice. Ongoing surgical and postsurgical advances and emergent factors that predispose patients to these tumors have changed the treatment paradigm. Having a keen understanding of diagnostic, surgical, and nonsurgical treatment options is key to identifying, treating, or referring patients with potential cutaneous malignancies. While Brian R. Gastman's Cutaneous Malignancies: A Surgical Perspective is the first of its kind to emphasize surgical management of skin cancer, several sections are devoted to systemic nonsurgical therapies affecting patient care and surgical intervention. Topics encompassed include prevention, diagnosis, medication management, appropriate margin size, reconstruction methods, and the importance of stellar dermatopathology. Key Highlights The role of Mohs micrographic surgery and radiation in skin cancer treatment Treatment approaches for the two most common forms of skin cancer respectively, basal cell carcinoma and squamous cell carcinoma Surgical treatment of cutaneous malignant melanoma and other high-risk malignancies Clinical insights on completion lymphadenectomy and sentinel node biopsy for melanoma, two topics rarely addressed in context with skin cancer Diagnosis and treatment of rare malignancies including Merkel cell carcinoma, dermatofibrosarcoma protuberans, cutaneous angiosarcoma, and cutaneous leiomyosarcoma More than 400 high-quality illustrations further delineate surgical modalities Edited by an esteemed dual board certified plastic surgeon and otolaryngologist, this definitive book is the most complete guide to surgical management of skin cancer. It is essential reading for plastic surgeons, dermatologists, otolaryngologists, and all clinicians who treat or refer patients with suspected skin cancer.

The first edition of this book was judged by many to be the best available atlas of upper gastrointestinal and hepato-pancreato-biliary surgery. The second edition builds upon this success by covering all of the significant intervening developments, including both new procedures and adaptations of established techniques. The atlas opens with an introductory section on the basic principles of operative surgery. All of the important surgical techniques are then presented in a series of sections devoted to the esophagus, stomach, and duodenum, the liver, the biliary system, portal hypertension, the pancreas, and the spleen. General, oncologic, and transplantation surgical procedures are described step by step with the aid of more than 900 superb illustrations drawn by a team of artists with extensive experience. The contributors were selected on the basis of their extensive experience in the procedures discussed and most are established educators.

A unique resource on glioma leverages advances and firsthand insights to enact meaningful change Glioblastoma (GBM) or glioma is an extremely aggressive and malignant brain tumor, with cell infiltration, rapid invasion, and a high frequency of relapse. The Glioma Book by neurosurgeon Michael Sughrue is a highly personal book - a culmination of two years of writing and more than 1,000 surgeries. It presents a unique viewpoint with the potential to transform the traditional paradigm that too often informs treatment of this universally fatal brain tumor. The book reinterprets the role of the cerebrum and sub-cortex, leverages scientific advances to improve cytoreduction and reduce neurological deficits, and challenges the myth of the "inoperable" glioma. This is the first step-by-step technical guide focused on aggressively resecting different types of gliomas. The book is logically organized, starting with a foundation of fundamental knowledge, then progressing to practical applications. Chapters focus on the skills necessary to perform glioma surgery, specific techniques, and systematic approaches to gliomas in different brain regions. Numerous case examples illuminate concepts introduced earlier in the book and explain how to perform these procedures About 30 high quality videos posted online provide insightful procedural guidance The role of connectomic imaging in visualizing the cerebrum, and other innovative techniques including awake brain mapping and diffusion tensor tractography Neurosurgeons who embrace the concepts in this book will realize they can change the glioma treatment paradigm. Continually improving techniques and viewing a glioma diagnosis as a battle for a patient's life, rather than an exercise in inevitable failure can impart progress in treating this devastating disease. This book includes complimentary access to a digital copy on https://medone.thieme.com.

In the past, liver resections and liver transplantations were performed by different surgical teams, with very little interplay between the two. However, the evolution toward more complex operations called for an increasingly intense interaction between these surgical techniques: split liver and living donor liver transplantation have become popular in the transplant community, utilizing the Coinaud segmental anatomy in a very sophisticated way, while portal and arterial resection and reconstruction have become indispensable methods for treating Klatskin tumors infiltrating the hepatic hilum. This book offers a complete overview of the connections between liver transplantation and hepatobiliary surgery. It focuses on ex situ techniques for resection of tumors at the suprahepatic confluence, with or without venous reconstruction, and on total vascular exclusion of the liver with the aid of a venovenous bypass that should be a surgical option for referral centers in hepatopancreatobiliary surgery. By taking into consideration the development of minimally invasive liver surgery, it will introduce readers to a variety of new perspectives such as: vascular exclusion techniques with or without extracorporeal circulation, hemodynamic implications and lessons learned from liver transplant surgery, and technical details on pediatric transplantation and its informative role in modern biliary tract surgery.

Management of Soft Tissue Sarcoma addresses the diagnosis and best current management of adult soft tissue sarcomas. Edited by world renowned experts, this book delineates and discusses each different sarcoma subtype individually. Both clinical and molecular diagnoses are addressed, and tumor histopathology is employed as the basis of treatment recommendations including surgery, radiation therapy, systemic therapy and novel therapeutics.

In recent years, great advances in translational research have led to new paradigms in the treatment of cancers of the head and neck. Written by leading international physicians and investigators, this innovative multi-disciplinary book presents the most up-to-date research and clinical approaches. Coverage is given to progress in a variety of clinical settings, including programs of organ and function preservation, curative treatments, unresectable disease, adjuvant treatments in high-risk patients, and recurrent/metastatic disease. Complementary to the techniques of surgery, radiotherapy, and systemic treatments, the authors present data on epidemiology, molecular pathology, normal tissue complications, rehabilitation, palliative care, and treatment in the elderly. State-of-the-art functional imaging is elucidated; and the latest developments in high precision techniques in irradiation, sequencing of chemo- and radiotherapy, as well as the integration of biomolecular therapies into cytotoxic treatments are explored.

This multidisciplinary textbook is designed to be the standard on the subject and is geared for use by physicians who are involved in the care and/or diagnosis of cancer patients, including general surgeons, nuclear medicine physicians, oncologists, and pathologists. Contributors to this book represent key members of the care team and include some of the most prestigious names in the field. Comprehensive coverage is provided on all aspects of radioguided surgery, including radiation protection, training, sentinel lymph node biopsy, and non-sentinel lymph node applications for various cancers, tumors, and lesions. Practical information is readily accessible and throughout there is an emphasis on improved decision making. For instance, discussions of lymph node staging, anatomy, and physiology provide rationale for performing radioguided studies and techniques. Sentinel node localization and radioimmunoguided therapy are compared and contrasted in order to define the appropriate use of each modality. Tables present the indications, performance, and interpretation of procedures at a glance. Key data on radiopharmaceuticals and sentinel node localization devices are centrally compiled so that readers can easily identify the characteristics of equipment and agents. A wealth of illustrations completes this authoritative reference and enhances the effective application of new concepts.

This handbook provides surgeons with updated information about the current status, perspectives and controversies for staging and treating cancer through minimal access procedures. The authors discuss the biology of minimal access, techniques, the equipment used, the perspectives and controversies surrounding the procedures in cancer management.

This guide provides practical information that will assist clinicians involved in the diagnosis, assessment, treatment, and follow-up care of patients with triple-negative breast cancer. After opening chapters on the pathologic evaluation, clinical presentation, genetics, and imaging features, the full range of current treatment approaches is thoroughly reviewed from a multidisciplinary perspective. Readers will find up-to-date information and guidance on surgical management, radiation therapy, tailored adjuvant therapy, neoadjuvant treatment, systemic treatment for metastatic disease, molecular profiling, and targeted therapy. The coverage is completed by discussion of special issues in young women with triple-negative breast cancer and individualization of the management approach in older patients affected with the disease. All healthcare professionals who care for patients with triple-negative breast cancer will find the book to be an invaluable source of expert advice on the issues faced in real-world practice.

This highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease. It starts off by presenting the molecular mechanisms, genetic testing and counseling, and variants of unknown significance (VUS) to help readers understand the contemporary interpretation of the disease. Further chapters focus on the surveillance, diagnosis and treatment, including chemoprevention, risk reduction and drug development based on molecular mechanisms. It also includes a chapter on the latest findings from the HBOC database, ethical issues and the parp inhibitors, and discusses innovative thinking to manage and understand the disease. Hereditary Breast and Ovarian Cancer - Molecular Mechanism and Clinical Practice offers breast surgeons, medical oncologists, gynecological oncologists and genetic counselors a comprehensive overview of the disease. Providing insights into recent scientific findings and further avenues for investigation, it is also a thought-provoking and informative read for researchers and scholars.

The book encompasses the different concepts and designs using magnets for surgical purposes. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. The text reviews new data about interventions in all medical and surgical fields. Written by experts in their fields, topics focus on endoluminal and laparoscopic operations, techniques from vascular and GI anastomosis. The book demonstrates the use of magnets to treat a variety of diseases such as reflux, back pain, and fecal incontinence. The reader will learn how to retract and gain exposure, dissect tissue planes, achieve hemostasis, and create anastomosis in a totally different way. Physical properties of external surface and internal magnets are discussed. The authors emphasize the importance of partnering with industry leaders to develop novel surgical tools. By harnessing the power of attraction, the energy and might of magnets, Magnetic Surgery serves as a valuable resource for clinicians, surgeons and researchers in biomedical engineering interested in this form of energy and physical metal properties. In utilizing these properties, the book seeks to improve surgical outcomes of patients worldwide.

This comprehensive, illustrated guide presents representative general surgery, including gastrointestinal tract, hepatobiliary and inguinal hernia. Surgery is generally based on the microanatomy; however, in practice surgery involves more dynamic and floating anatomy. In the last decade, the methods have been constantly improved, shedding new light on classical anatomical science. Laparoscopic is one such methodology. All illustrations presented in this book have been drawn by the author - a pioneering surgeon - and show real-world procedures. All the methods introduced are practical and have been refined based on the precise clinical and embryological anatomy. This unique book offers readers essential insights into efficient and high-integrity surgeries in abdominal region. As such, it is a valuable resource for all gastrointestinal surgeons.

Surgical oncology is now a recognized specialty in the US and several European countries, and cancer surgery takes up a significant part of any general surgeon's workload. This thoroughly updated second edition of this bestseller is officially endorsed as a textbook for the syllabus and curriculum of the UEMS examination in Surgical Oncology, which is administered by ESSO (European Society for Surgical Oncology). The examination is for trainees at the end of training or established consultants seeking to expand their accreditation.

This book examines the considerations, drawbacks, and advancements minimally invasive techniques have provided in the evaluation, management, and outcomes across a broad range of colorectal disease and procedures. For some readers of this book, a minimally invasive approach to colorectal disease may add a new dimension to the management of these patients. For others, it is the opportunity to learn helpful tips, specifics about a certain procedure, or to fine tune what has already become a routine part of their practice. Even if you have successfully overcome many of the technical challenges of minimally invasive surgery, the preoperative evaluation, perioperative decision-making, and management of postoperative complications can be demanding and consuming. Wherever you may be on this spectrum, Robotic Approaches to Colorectal Surgery is a useful resource to surgeons.

Ein Klassiker von zeitlosem Wert auch f r das 21.Jahrhundert!

Die anschauliche Beschreibung des Vorgehens in Wort und Bild, die der 1987 erschienene thoraxchirurgische Band aus der Kirschnerschen Operationslehre bietet, ist f r viele Operationen unver ndert g ltig.

Durch die Sonderausgabe ist der Band allen Chirurgen, die Eingriffe an der Brust und in der Brusth hle vornehmen, wieder zug nglich. Ein neu verfasstes Vorwort der Herausgeber pr zisiert den aktuellen Stellenwert der dargestellten Verfahren.