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Oxford Textbook of Cancer Biology (Hardcover)
Loot Price: R5,048
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Oxford Textbook of Cancer Biology (Hardcover)
Series: Oxford Textbooks in Oncology
Expected to ship within 12 - 17 working days
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The study of the biology of tumours has grown to become markedly
interdisciplinary, involving chemists, statisticians,
epidemiologists, mathematicians, bioinformaticians, and computer
scientists alongside biologists, geneticists, and clinicians. The
Oxford Textbook of Cancer Biology brings together the most
up-to-date developments from different branches of research into
one coherent volume, providing a comprehensive and current account
of this rapidly evolving field. Structured in eight sections, the
book starts with a review of the development and biology of
multi-cellular organisms, how they maintain a healthy homeostasis
in an individual, and a description of the molecular basis of
cancer development. The book then illustrates, as once cells become
neoplastic, their signalling network is altered and pathological
behaviour follows. It explores the changes that cancer cells can
induce in nearby normal tissue, the new relationship established
between them and the stroma, and the interaction between the immune
system and tumour growth. The authors illustrate the contribution
provided by high throughput techniques to map cancer at different
levels, from genomic sequencing to cellular metabolic functions,
and how information technology, with its vast amounts of data, is
integrated with traditional cell biology to provide a global view
of the disease. The effect of the different types of treatments on
the biology of the neoplastic cells are explored to understand on
the one side, why some treatments succeed, and on the other, how
they can affect the biology of resistant and recurrent disease. The
book concludes by summarizing what we know to date about cancer,
and in what direction our understanding of cancer is moving. Edited
by leading authorities in the field with an international team of
contributors, this book is an essential resource for scholars and
professionals working in the wide variety of sub-disciplines that
make up today's cancer research and treatment community. It is
written not only for consultation, but also for easy cover-to-cover
reading.
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