The eighth volume of Evidence-based Clinical Chinese Medicine aims to provide a multi-faceted 'whole evidence' analysis of the management of Alzheimer's disease in Chinese and integrative medicine.Beginning with overviews of how Alzheimer's disease is conceptualised and managed in both conventional medicine and contemporary Chinese medicine, the authors then provide detailed analyses of how dementia and memory disorders were treated with herbal medicine and acupuncture in past eras.In the subsequent chapters, the authors comprehensively review the current state of the clinical trial evidence for Chinese herbal medicines, acupuncture and other Chinese medicine therapies in the management of Alzheimer's disease, as well as analyse and evaluate the results of these studies from an evidence-based medicine perspective. The outcomes of these analyses are summarised and discussed in terms of their implications for the clinical practice of Chinese medicine and for future research.This book can inform clinicians and students in the fields of integrative and Chinese medicine of the current state of the evidence for a range of Chinese medicine therapies in Alzheimer's disease, including the use of particular herbal formulas and acupuncture treatments in order to assist clinicians in making evidence-based decisions in patient care.

Novel drug delivery systems cover the approaches, formulation, technologies, and modes for transporting any pharmaceutical compound throughout the body to safely get the desired effect. A growing area of research is the use of herbal formulations for disease therapy. In combining these two areas of research, that of novel drug delivery systems and that of herbal formulations, the usefulness of herbs is not only proved but its future applications and effectiveness are studied. The move towards herbal-based novel drug delivery systems can benefit society in a multitude of advantageous ways. Enhancing the Therapeutic Efficacy of Herbal Formulations discusses and explores the ways of preparing herbal formulations loaded in novel drug delivery systems and the resultant improvement in efficacy of the effected drugs/herbs already available on the market. The chapters will highlight traditional and herbal formulations, the effects of novel drug delivery systems on herbal formulations, and the safe and effective preparation and effects of herbal formulations as a therapeutic intervention. This book is ideal for pharmacists, doctors, and researchers specializing in herbal therapeutics, along with practitioners, researchers, academicians, and students interested in how herbal-based novel drug delivery systems can benefit society.

Type 2 diabetes mellitus is a chronic progressive disease characterised by hyperglycaemia. It affects many people around the world and creates burden for the individual as well as the economy. Chinese medicine can be used to support the management of Type 2 diabetes mellitus symptoms. Chapter 1 of the book summarises the conventional understanding of Type 2 diabetes mellitus, including aetiology, diagnosis and current available treatments.This book uses the 'whole evidence' approach to give an overview of the available evidence for Chinese medicine treatment for Type 2 diabetes mellitus, from classical literature to clinical evidence. Evidence from clinical studies are evaluated using high-quality and rigorous scientific methodology. Clinical trial literature of Chinese medicine treatments for Type 2 diabetes mellitus are described, with treatment modalities including Chinese herbal medicine, acupuncture and other Chinese medicine therapies. The findings are analysed and potential implications for clinical practice and research are explored. Experimental studies that describe the potential mechanisms of action of key herbs are summarised. Current evidence of Chinese medicine for Type 2 diabetes mellitus is synthesised in the final chapter, and suggestions for contemporary clinical practice and future research are also offered.Targeted at clinicians and students of Chinese and integrative medicine, this book is a convenient reference that provides comprehensive synthesis of both classical and contemporary knowledge, which can support and be incorporated into their clinical practice.

While biotechnological advances, genomics and high throughput screenings or combinatorial and asymmetric syntheses are opening new opportunities in drug discovery, the industry is facing serious innovation deficit. The total number of new molecules registered per year has dropped in contrast to expected increase. Post marketing failures of blockbuster drugs have become major concerns of industries. On the other side, globally there is a major shift to sue of traditional medicine involving complementary and alternative therapies. Ethnopharmacology and traditional medicines have contributed in past significantly in the process of natural product drug discovery. There are two clear tracks where ethnopharmacology has potential to contribute in future drug research. First, as a discovery engine to provide new targets, leads, and second, use of quality assured and standardized traditional medicines. In this scenario, it is important to understand the mechanisms of drug discovery and pharmaceutical development with a focus on herbal drugs and neutraceutical. This book provides historical perspective, future prospects and significance of ethnopharmacology in drug research. It also provides important steps in botanical drug discovery and development including bioprospecting, quality control, standardization, pharmaceutics, stability, pharmacokinetics, and bioavailability with examples from ethnopharmacology and herbal medicine. One of the important feature of this book is to give an excellent insight to Good Laboratory and Good Clinical Practices along with very useful summary steps involved in filing IND or NDA of botanical products. The book also gives Regulators' perspective of validating claims and how ethnopharmacological or traditional medicines need different approach.

Menopausal symptoms can significantly reduce women's quality of life, and may last for several years. Women who seek relief from symptoms often turn to complementary therapies, including Chinese medicine. The latest in the Evidence-based Clinical Chinese Medicine series uses a 'whole evidence' approach to summarise the management of menopausal symptoms with Chinese medicine. The first chapter describes the conventional medicine understanding of menopause, including common signs and symptoms, diagnosis and treatment. The Chinese medicine conceptualisation of menopause, both in contemporary and classical literature, is reviewed and discussed.The evidence from clinical studies is reviewed using internationally accepted scientific methods. Systematic reviews describe the treatments used in clinical studies, and analyse the effectiveness of Chinese herbal medicines, acupuncture and related therapies, other Chinese medicine therapies, and combinations of Chinese medicine therapies. Experimental studies that describe the potential mechanisms of action of key herbs are summarised. The final chapter synthesises the current evidence and offers suggestions for contemporary clinical practice and future research.This book is a handy desktop reference for both clinicians and students of Chinese and integrative medicine. It provides a comprehensive synthesis of both traditional and contemporary knowledge that can inform clinical decision-making.

Urinary tract infection is a common clinical condition with a significant health burden. This latest volume, Vol. 22 in the Evidence-based Clinical Chinese Medicine series, uses a 'whole evidence' approach to summarise management of urinary tract infection with Chinese medicine. The first chapter provides an overview of the clinical presentation, diagnosis and treatment with conventional medicine. The conceptualisation of urinary tract infection in both contemporary and classical Chinese medicine literature is reviewed and analysed. Attention is then turned to the evidence from clinical studies. Systematic reviews, using internationally accepted scientific methods, describe the treatments tested in clinical studies and the effects of Chinese herbal medicine, acupuncture and related therapies, and combinations of these therapies for urinary tract infection. The potential mechanisms of action for some of the key herbs are summarised, based on analysis of experimental studies. The final chapter summarises the current state of evidence and offers suggestions for contemporary clinical practice and future research.This book is a handy desktop reference for both clinicians and students of Chinese and integrative medicine. It provides a comprehensive synthesis of both traditional and contemporary knowledge that can inform clinical decision-making.This book provides an in-depth analysis of Chinese medicine management of urinary tract infection.

Chronic Cough is the 20th volume of the Evidence-based Clinical Chinese Medicine series. It provides a multi-faceted 'whole evidence' analysis of the management of chronic cough, including cough variant asthma, upper airways cough syndrome, and gastroesophageal reflux disease in Chinese medicine. Evidence from the classical Chinese medicine literature, contemporary clinical literature, the outcomes of clinical trials and experimental studies are reviewed, analysed and synthesised. The data from all these sources are condensed to provide evidence-based summaries and identity implications for the clinical practice of Chinese medicine and for future research. This book can inform clinicians and students in the fields of integrative medicine and Chinese medicine regarding contemporary practice and the current evidence base for a range of Chinese medicine therapies used in the management of chronic cough, including herbal formulas and acupuncture treatments, in order to assist clinicians in making evidence-based decisions in patient care.Currently, Chinese medicine practitioners who develop a special interest in a particular health condition, such as chronic cough need to consult a diversity of resources to expand their knowledge. Such sources typically included specialty books and journal articles sourced from biomedical databases published in Chinese and English. However, not all practitioners have access to such sources to obtain information on the evidence-based management of chronic cough. By providing all this information in one handy, easy to use reference, this book allows practitioners to focus on providing high quality health care, with the knowledge it is based on the best available evidence.

Consolidating unbiased, peer-reviewed information from many sources, this book provides a one-stop resource on the use and health benefits of 50 different herbs. While the use of herbs and herbal supplements seem an attractive alternate to man-made therapies, such use is often inspired by anecdotal evidence rather than sound clinical research. Healthy Herbs: Fact versus Fiction examines the health claims associated with 50 popular herbs and coalesces the clinical findings on these natural substances. This useful resource examines the history and use of herbs and will ultimately help readers make informed decisions regarding these natural therapies. The findings in the book are culled from credible sources such as international, peer-reviewed journals, providing nomenclature, history, common usage, effectiveness, and additional suggested reading on selected herbs and herbal supplements. Rather than advocating for or against alternative medicine or herb use, the book provides authoritative, unbiased, and evidence-based information so the health conscious can make informed decisions for themselves. Each entry contains a concise bibliography of resources and references

This seventeenth volume of the Evidence-based Clinical Chinese Medicine series aims to provide a multi-faceted 'whole evidence' analysis of the management of Colorectal Cancer in integrative Chinese medicine.Beginning with overviews of how colorectal cancer is conceptualised and managed in both conventional medicine and contemporary Chinese medicine, the authors then provide detailed analyses of how colorectal cancer and related disorders were treated with herbal medicine and acupuncture in past eras.In the subsequent chapters, the authors comprehensively review the current state of the clinical trial evidence for Chinese herbal medicines (Chapter 5), acupuncture (Chapter 7), other Chinese medicine therapies (Chapter 8) and combination Chinese medicine therapies (Chapter 9) in the management of colorectal cancer, as well as analyse and evaluate the results of these studies from an evidence-based medicine perspective. Chapter 6 provides a review and a summary of the experimental evidence for the bioactivity of commonly used Chinese herbs. The outcomes of these analyses are summarised and discussed in Chapter 10 which identifies implications for the clinical practice of Chinese medicine and for future research.This book can inform clinicians and students in the fields of integrative medicine and Chinese medicine regarding contemporary practice and the current evidence-base for a range of Chinese medicine therapies used in the management of colorectal cancer, including herbal formulas and acupuncture treatments, in order to assist clinicians in making evidence-based decisions in patient care.The following features mark the importance of this book in the field: