Leon N. Moses In June 1991, the Transportation Center at Northwestern University sponsored Hazmat Transport '91: A National Conference on the Transportation of Hazardous Materials and Wastes. The faculty associated with the center were aware that there had been many professional, industrial and government conferences and meetings on the subject. However, they believed that the unique capacity of the Transportation Center to bring together leaders from industry and government, as well as leading scholars from economics, law, engineering, psychology and sociology who have done research on the problems associated with the transportation of hazardous materials and wastes (hazmats), could produce a set of integrated insights and understandings that would go well beyond those of previous conferences. The papers that make up this volume were all delivered at Hazmat Transport '91. From a legislative point of view, they tend to deal with issues associated with the Hazardous Materials Transportation Act of 1975 (HMTA), the original act passed to regulate the transportation of hazardous materials, and the Hazardous Materials Transportation Uniform Safety Act of 1990 (HMTVSA). There were talks and papers presented at the conference that focused on other recent legislation and transportation issues with which HMTUSA does not deal. The conference proceedings volume also had discussions and papers on significant managerial and regulatory issues that could not be included in this volume because of constraints on its size. Therefore, this essay is made up of three parts.

This book encourages and demonstrates an innovative approach to the design and operation of urban wastewater systems: integrated modelling and control. Consideration of sewer system, wastewater treatment plant and receiving water body as a single system (rather than as three moderately independent units as before) opens up new types of analyses and new control algorithms for urban wastewater systems. After a comprehensive review of the literature of various fields including processes affecting water flow and quality in urban wastewater systems and their description by different types of models, this book also introduces some of the fundamental concepts of the operation of such systems. It discusses conventional as well as innovative control approaches - ranging from control by simple set-points to elaborate hierarchical control concepts taking into account the water flow and the quality of sewer systems, treatment plants and receiving water body. Thus it will enable the researcher as well as the practising engineer to analyse and to implement various types of control for a particular case study site.In order to illustrate the concepts developed, a detailed simulation study, covering the complete urban wastewater system, is presented. The conclusions drawn demonstrate that the application of innovative control concepts can lead to improved performance of wastewater systems. In addition, a comprehensive survey of mathematical optimisation methods is presented. This book can assist the practising engineer and the student to gain knowledge of all aspects of wastewater systems. To the researcher, this book provides a thorough survey of existing simulation and control concepts and inspiration for further work.

When, in 1966, the Gennan Research Society directed the attention of oceanographers in the Federal Republic of Ger many to problems of marine pollution, I was not enthusiastic. Emphasis on this problem area meant that other important research plans had to be postponed. But the lectures at the Third International Oceanographic Congress, September 1970, in Tokyo, and at the FAO Conference on Marine Pollution and its Effects on Living Resources and Fishing, December 1970, in Rome, convinced me that research on problems of marine pollution is a social obligation, and that the oceanographer has to take a stand. I issued public warnings about the continuing use of pesticides and had to defend myself against protests by the fishing industry and many colleagues who were, in Novem ber 1970, unaware of the extent of the threat. Thus, I was required by my profession to acquire an overview of the prob lems of ocean pollution. In 1971 I only needed to familiarize myself with some one hundred bibliographical items. In the interim, the flood of data has risen dramatically, and in the year 1975, no fewer than 868 publications under the heading of "Marine Pollution" were reported (Table 1). It is, therefore, more and more diffi cult to distinguish new results of scientific research from the many repetitions and variations, and I fear that from year to year my efforts to illustrate the actual status of the problem at a given moment will be subject to more gaps."

Disposal of organic sludge and liquid agricultural wastes is a universal problem. Their production cannot be halted and as steps are taken to maintain or improve the quality of rivers and lakes it grows in quanti ty. The Commission's early awareness of the need for action to prepare for substantial growth in the Community's' sludge disposal problem led to the setting up of the COST 68 project to coordinate and guide European research and development work with particular emphasis on recycling sludge to agricultural land. Two years ago the field of research activi ties was extended to liquid agricultural wastes. This Symposium is the latest opportunity to provide a comprehensive review of the results of the project, to define current trends in practice and to establish by discussion the priorities for research over the next few years. The development of instrumentation and of analytical techniques during the period has extended our knowledge of the organic and inorganic constituents of sewage sludge and agricultural wastes and enabled us more readily to identify and measure the risks to which our general environment may be exposed when disposing of it. This evolution of understanding is a continuing process and an essential guide to the modification of disposal practices to achieve safer and more efficient operations. However, it is important to take a broad view of the application of research findings in the light of the considerable contrast in conditions in different parts of the world.

Reviews of Environmental Contamination and Toxicology provides detailed review articles concerned with aspects of chemical contaminants, including pesticides, in the total environment with toxicological considerations and consequences.

Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.

The subject of rainfall-runoff modeling involves a wide spectrum of topics. Fundamental to each topic is the problem of accurately computing runoff at a point given rainfall data at another point. The fact that there is currently no one universally accepted approach to computing runoff, given rainfall data, indicates that a purely deter ministic solution to the problem has not yet been found. The technology employed in the modern rainfall-runoff models has evolved substantially over the last two decades, with computer models becoming increasingly more complex in their detail of describing the hydrologic and hydraulic processes which occur in the catchment. But despite the advances in including this additional detail, the level of error in runoff estimates (given rainfall) does not seem to be significantly changed with increasing model complexity; in fact it is not uncommon for the model's level of accuracy to deteriorate with increasing complexity. In a latter section of this chapter, a literature review of the state-of-the-art in rainfall-runoff modeling is compiled which includes many of the concerns noted by rainfall-runoff modelers. The review indicates that there is still no deterministic solution to the rainfall-runoff modeling problem, and that the error in runoff estimates produced from rainfall-runoff models is of such magnitude that they should not be simply ignored."

The growing perception of the public and politicians that life is extremely risky has led to a dramatic and increasing interest in risk analysis. The risks may be very diverse as demonstrated by the range of subjects covered at the annual meetings of the Society for Risk Analysis. There is a need to pause and see how well the present approaches are serving the nation. The theme, "Setting National Priorities," which was chosen for the 1987 SRA Annual Meeting, reflects the concern that in dealing with individual kinds of risks, society may be more concerned with the trees than the forest. It is surprising how little attention is being given to the holistic aspects of risk. Who, for instance, is responsible for a national strategy to manage the reduction of health or other risks? Individual agencies have the responsibility for specific patterns of exposure, but these are not integrated and balanced to determine how the nation as a whole can obtain the greatest benefit for the very large investment which is made in risk-related research and analysis.

As society has become increasingly aware of the potential threats to human health due to exposures to toxic chemicals in the environment and the workplace and in consumer products, it has placed increased demands upon the still-fledgling science of toxicology. As is often the case when science is called upon to supply firm answers when pertinent information and fundamental knowledge are lack ing, both the scientific and the social issues become confused and new tensions develop. One of the major purposes of this book is to focus on those aspects of the science of toxicology that pertain most to social issues-namely, analysis of risk for purposes of human health protection. Although it is apparent that the discipline of toxicology is not yet prepared to provide firm answers to many questions concerning human risk, it is important that the rigorously derived information be used in the most objective and logical way to yield the closest approximation to the truth. This book is designed to sup ply as much guidance for such tasks as is permitted by the current state of our knowledge. Its emphasis is thus placed on interpretation of toxicity data (broadly defined) for assessing risks to human health. In this way, it differs from other basic toxicology texts, most of which emphasize methods for performing studies or describe various toxicological endpoints and classes of toxic agents."

The difficulties associated with making risk assessments on the basis of experimental results are familiar to practitioners in many fields engineering, epidemiology, chemistry, etc. These difficulties are particularly common in problems that have dynamic and stochastic characteristics driven by multiple purposes and goals, with complex interconnections and inter dependencies. Acquiring an appropriate data base, processing and analyzing model results, and transmitting these results at an appropriate technical, social, political, and institutional level are additional difficulties that must be addressed. This book is grounded on the premise that risks are best assessed on the basis of experimental results and sound mathematical analyses, coupled with the knowledge of experts. The carcinogenicity prediction and battery selection (ePBS) approach described herein provides a systematic mechan ism-a synthesis of systems and statistical and decision analyses-to aid researchers and decision makers in the critical field of carcinogenicity prediction in selecting an appropriate battery of tests to use and in translating experimental results into information that can be used as an aid to decision making."

The Council of the North Atlantic Treaty Organization (NATO) established the "Committee on the Challenges of Modern Society" (CCMS) in 1969. The CCMS was charged with developing meaningful environmental and social programmes for solving existing problems and developing long-range goals for environmental protection. In 1983, at the Fall Plenary of the CCMS, the Norwegian delegate Dr. H.C. Christensen, proposed a Pilot Study on "Risk Management of Chemicals in the Environment". A draft proposal, written by Dr. Kari Kveseth of the Center for Industrial Research in Oslo, was presented. Dr. Christensen also informed the participants at the meeting that Norway was willing to act as the Pilot Country. The project was initially planned for 3 years, but it was later extended through 1987. The inaugural meeting was held in Oslo in April 1984 with participants from Denmark, Greece, France and Italy, in addition to representatives from several Norwegian institutions. The attendees concluded that a Pilot Study, as delineated in the draft proposal, would be useful, and it was decided to work out a detailed project plan based on the proposal.

As we enter the nineties, there is worldwide awareness that the future of all mankind is inexorably linked by the world we share, and its response to man's activities. Lasers and the optical sciences have brought powerful tools to measure and understand our environment. LIDAR (laser radar) and laser fluorescence allow us to measure atmospheric and oceanic pollutants, as well as industrial emissions, from many kilometers distance. And a variety of sensitive laser-based spectroscopic techniques permit the accurate analysis of heavy metals and other trace elements in the environment. In September 1989, an international group of scientists me.t in Erice, Sicily, for the 14th Course of the International School of Quant~ Electronics. This Course was devoted to "Optoelectronics for Envi~onmental Science", and was ably directed by Prof. V. S. Letokhov of the USSR Institute of Spectroscopy and Prof. A. M. Scheggi of the C.N.R. Electro magnetic Waves Institute, Florence, Italy. This book gives the proceedings of that conference, which covered not only basic tutorial papers but also reports on the latest research results. The first half of this volume describes the techniques used for direct "In-Situ Measurements" of the environment. In "Techniques and Programs", four chapters and one extended abstract give tutorial discussions of the most important remote sensing techniques: LIDAR, laser fluorescence, and optical fiber sensors, plus a description of the Italian program in this area.

Bioremediation is a rapidly advancing field and the technology has been applied successfully to remediate many contaminated sites. The goal of every soil remediation method is to enhance the degradation, transformation, or detoxification of pollutants and to protect, maintain and sustain environmental quality.

Advances in our understanding of the ecology of microbial communities capable of breaking down various pollutants and the molecular and biochemical mechanisms by which biodegradation occurs have helped us in developing practical soil bioremediation strategies. Chapters dealing with the application of biological methods to soil remediation are contributed from experts authorities in the area of environmental science including microbiology and molecular biology from academic institutions and industry."

1 2 J. H. SCHROEDER and B. H. PURSER 1 Introduction A symposium convened during the Vth International Coral Reef Congress in Papeete, Tahiti, 1985, encouraged the editors to assemble this volume of case studies by participating and, especially, by nonparticipating scientists. An attempt was made to include case studies from various regions and geological periods, carried out on various scales from regional to ultrastructural. We hope to present an overall view of reef diagenesis. Although the volume focuses on reef diagenesis, fields also to be considered are biology, paleontology, and sedimentary facies distribution, as they provide the context and, to some extent, encompass the determinants of diagenetic processes. The scope has been limited to reef diagenesis because we feel that reefs have relatively clearly defined geometries, which facilitate the evaluation of diagenetic trends and the definition of diagenetic models. On the other hand, their many different components make reefs somewhat more complex than other deposits, and this creates difficulties in deciphering diagenetic histories; the study of reefs, therefore, is not the simplest manner of solving the many problems relating to carbonate diagenesis. An additional reason for evaluating reef diagenesis is the reservoir potential of these carbonate bodies. To illustrate the point, in the recent collection of 35 case studies of carbonate reservoirs (Roehl and Choquette 1985), reefs were involved in 15. The emphasis on porosity development in many studies of the present volume is therefore not of mere academic interest.

Contained in this volume are the proceedings of the international conference on the "Genetic Toxicology of Complex Mixtures," held from July 4-7, 1989, in Washington, DC. This meeting was a satellite of the "Fifth International Conference on Environmental Mutagens" and the seventh in a biennial series of conferences on "Short-term Bioassays in the Analysis of Complex Environmental Mixtures. " Our central objective in calling together key researchers from around the world was to extend our knowledge of the application of the methods of genetic toxicology and analytical chemistry in the evaluation of chemical mixtures as they exist in the environment. This conference emphasized the study of genotoxicants in air and water, and the assessment of human exposure and cancer risk. The latest strategies and methodologies for biomonitoring of genotoxicants (including transformation products) were described in the context of the ambient environment. Source character ization and source apportionment were discussed as an aid to understand ing the origin and relative contribution of various kinds of complex mix tures to the ambient environment. Similarly, investigations of genotoxi cants found in the indoor environment (sidestream cigarette smoke) and in drinking water (chlorohydroxyfuranones) were given special attention in terms of their potential health impacts. New molecular techniques were described to enable more precise quantitation of internal dose and dose to-target tissues. The emphasis of presentations on exposures/effects assessment was on integrated quantitative evaluation of human exposure and potential health effects.

Life is often considered to be a journey. The lifecycle of waste can similarly to be a journey from the cradle (when an item becomes be considered is placed in the dustbin) to the grave (when value valueless and, usually, is restored by creating usable material or energy; or the waste is transformed into emissions to water or air, or into inert material placed in a landfill). of this book This preface provides a route map for the journey the reader will undertake. Who? Who are the intended readers of this book? Waste managers (whether in public service or private companies) will find a holistic approach for improving the environmental quality and the of managing waste. The book contains general principles economic cost based on cutting edge experience being developed across Europe. Detailed data and a computer model will enable operations managers to develop data-based improvements to their systems. oj waste will be better able to understand how their actions can Producers influence the operation of environmentally improved waste management systems. oj products and packages will be better able to understand how Designers their design criteria can improve the compatibility of their product or package with developing, environmentally improved waste management systems. Waste data specialists (whether in laboratories, consultancies or environ mental managers of waste facilities) will see how the scope, quantity and quality of their data can be improved to help their colleagues design more effective waste management systems."

The complex topic of in-situ subsurface remediation technologies has been ad dressed at an international symposium at the Universitat Stuttgart on September 26 and 27, 1995, on the occasion of the inauguration of the research facility VEGAS (Versuchseinrichtung zur Grundwasser- und Altlastensanierung). The results are contained in this book with 22 contributions from leading experts in the field from Europe and North America. The book illustrates the role of large-scale experiments in groundwater and subsurface remediation research. The subtopics address the various links between conventional laboratory experiments, technology-scale experiments and field-site studies, showing the contribution of large-scale experiments to bridging the gap between small-scale investigations and large-scale field investigations (upscaling). The interdisciplinary nature of the problems requires a multidisciplinary approach. Therefore, the idea has been followed to bring together the various disciplines in volved in the different aspects and facets of subsurface flow, transport and trans as hydraulics and hydrology, physics, formation, involving such diverse disciplines chemistry, microbiology, geology, industrial, chemical and hydraulic engineering, mathematics and hydroinformatics. The individual contributions from these di versified fields address the subject from different angles in an attempt to form a coherent picture of the various aspects of the complex problems of subsurface remediation. The focus is on research approaches and strategies with respect to the development of new and improved technologies and to the role of large-scale experiments in research and application.

This book is the Proceedings of the International Conference on Trans portation, Storage, and Disposal of Hazardous Materials, which was held at the International Institute for Applied Systems Analysis (IIASA), 1-5 July 1985. The Conference brought together representatives of academia, business, and government from East and West to discuss the nature of current problems in the area of hazardous materials. An important objective of the Conference was to suggest steps that could be undertaken by industrial firms, the insurance industry, and govern ment agencies to improve the safety and efficiency with which hazar dous materials are produced and controlled in industrialized societies. Conference sponsors were IIASA, the Geneva Association, and the Center for Risk and Decision Processes of the University of Pennsyl vania. Additional financial support was received from the US Environ mental Protection Agency, the Monsanto Corporation, the Center for Organizational Innovation at the University of Pennsylvania, and the Canadian IIASA Committee. We are grateful to all of these institutions for their generous support of this Conference. Within IIASA, a long history of research in risk activities is evi dent. This owes much to the vision of IIASA's founding Director, Howard Raiffa, and program leaders who have promoted risk research at IIASA. The present Conference continued this tradition with the strong support of IIASA's current Director, Thomas H. Lee, and Deputy Director, Vitali Kaftanov."

In order to validate predictive models of the very long-term processes which affect the performance of radioactive waste repositories, there has been an increased interest in the information and understanding which can be obtained from studying similar mechanisms in natural systems. These "natural analogues," as they are known in the jargon of waste management, have been studied sporadically for many years, but there has been a considerable rejuvenation of interest in the last four years, possibly owing to the fact that performance assessment methodolo gy is gradually maturing to the point where it needs the kind of support which analogues can offer. Since 1982, the Commission of the European Communities has been involved in specific work on natural analogues in the framework of its activities on radioactive waste management, principally within the MIRAGE project which concerns migration of radionuclides in the geosphere. As a consequence, the Commission took the initiative, in 1985, of establish ing a Natural Analogue Working Group (NAWG) whose members can benefit from the overall expertise available for managing their own natural analogue research programmes. In this group, modeller' s requirements and the results of field research are exchanged at regular intervals. A number of wide-ranging investigation programmes, both on national and international scales. are currently underway or being initiated, and several of these have been discussed recently at the NAWG."

During late 1978, a symposium entitled "Science Underlying Radioactive Waste Management" was one component of the Annual Meet ing of the Materials Research Society held in Boston, Massachusetts. The purpose of this Symposium was to bring together for the first time the entire range of sciences that form the basis for the treatment, solidification and isolation of radioactive wastes. Some 79 papers were presented to an international audience of over 300. The Symposium was such an impressive success that another will be held at the 1979 Annual Meeting of the Materials Research Society. The proceedings of the forthcoming symposium will also be published and it is for this reason that the present volume has been desig nated Volume 1. The scope of the Symposium was defined by the following steer ing committee: Rustum Roy, The Pennsylvania State University (Chairman) Richard S. Claassen, Sandia Laboratories Don Ferguson, Oak Ridge National Laboratory Victor I. Spitsyn, U.S.S.R. Academy of Sciences, Moscow David B. Stewart, United States Geological Survey Torbjorn Westermark, Royal Institute of Technology, Stockholm. The program was organized by the following committee: Gregory J. McCarthy, The Pennsylvania State University (Cha- man) Harry C. Burkholder, Battelle Memorial Institute Arnold M. Friedman Argonne National Laboratory Werner Lutze, Hahn-Meitner Institut, Berlin John G. Moore, Oak Ridge National Laboratory Robert W. Potter, II, United States Geological Survey Richard L. Schwoebe1, Sandia Laboratories Roger W. Staehle, Ohio State University."

The elements in group 17 (VIlA) of the periodic table of elements-fluorine (F), chlorine (CI), bromine (Br), and iodine (I)-were designated by Berzelius as "halogens" (Greek hals, sea salt; gennao, I beget) because of their propensity to form salts. In this first of the two volumes of Bio chemistry of the Halogens, the biochemistry of the elemental halogens and inorganic halides is reviewed. Discovery, properties, and biochemistry of the elemental halogens are reviewed first (Chapter 1). This is followed by a review of the developments in the various areas of inorganic halide biochemistry (Chapters 2 through 5). The biochemistry of thyroid hor mones is considered in Chapter 6, while biohalogenation, an important link between inorganic and organic halogen biochemistry, is reviewed in Chapter 7. Chapter 8 covers the biochemistry of products produced by human-inspired halogenation, in particular, poly halogenated compounds that present environmental problems. In Chapter 9, the process is reversed and biodehalogenation is reviewed. In each subject, the attempt has been made to find an appropriate balance between depth and breadth of treatment, since a thorough, in depth review of this field would not be possible in a single volume. To provide readers not familiar with subjects with the necessary background to place subsequent discussions in perspective, brief historical develop ments of many of the topics are given."

Applied geophysics were developed to explore the raw materials needed by civilization. Today it is used to investigate the extent and nature of buried contaminated waste and leachates.
The book describes in detail, yet in a simple language, possibilities, advantages and shortcomings of geophysical methods. Case histories from the US and all over the world are discussed and richly illustrated, and cost estimates for geophysical surveys and criteria for the choice of methods and the compilation of tenders are provided.
The book will enable engineers, scientists and lawyers to appraise the possibilities of geophysics in the assessment of environmental risks.

The use of biotechnical processes in control of environmental pollution and in haz ardous waste treatment is viewed as an advantageous alternative or adduct to phys ical chemical treatment technologies. Yet, the development and implementation of both conventional and advanced biotechnologies in predictable and efficacious field applications suffer from numerous technical, regulatory, and societal uncertainties. With the application of modern molecular biology and genetic engineering, there is clear potential for biotechnical developments that will lead to breakthroughs in controlled and optimized hazardous waste treatment for in situ and unit process use. There is, however, great concern that the development of these technologies may be needlessly hindered in their applications and that the fundamental research base may not be able to sustain continued technology development. Some of these issues have been discussed in a fragmented fashion within the research and development community. A basic research agenda has been established to promote a sustainable cross-disciplinary technology base. This agenda includes developing new and improved strains for biodegradation, improving bioanalytical methods to measure strain and biodegradation performance, and providing an in tegrated environmental and reactor systems analysis approach for process control and optimization."

The study of the relationship between environmental pollution and human health is in its infancy. The number of substances and mixtures that have been identified in uncontrolled hazardous waste sites or that have been in advertently released into the environment is large and data on how thes~ substances are modified as they interact with one another as they migrate through soil, air, and water are limited. There are also limits on our un derstanding of how these substances may be ingested, inhaled, or absorbed by people. The complexity of possible interactions between biological, chemical, and physical components in a given environment makes it virtually impossible to evaluate the potential for adverse biological effects ade quately in the laboratory. Other, more comprehensive methods which provide realistic and interpretable results must be used. Many scientists believe that humans represent the ultimate sentinel species of a toxic exposure re sUlting from environmental pollution, however such exposures may also se verely impact environmental health. There exists a wide variety of organ isms in the natural environment that could be used to provide an early warning for potential human health effects as well as to indicate adverse ecological effects. The issue of effective utilization of sentinel species for environment al monitoring is a rapidly developing area of research which has grown in importance during the last decade.

Although present day politics seems to be preoccupied with questions of economic growth and full employment, the basic environmental problems stemming from the interactions of the economic sphere with global, regional and local environments persist and will have an even greater impact in the future. If economy and ecology are not reconciled in the years to come, mankind will not have a sustainable future on Earth. The typical negation of environmental problems in times of economic crisis is partially due to the fact that environmental and health damages of economic activities are neither priced nor included in our market price system. This allows politicians to focus their attention on insufficient economic indicators which do not reflect the actual development of the welfare of society. If economic lead indicators like GDP or balance of trade figures were better integrated with information on the environmental and health costs caused by the seemingly beneficial economic development, politicians might have better guidance as to what policy choices would benefit society most.