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The Pharmacology of Pain (Paperback, Softcover reprint of the original 1st ed. 1997)
Loot Price: R2,989
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The Pharmacology of Pain (Paperback, Softcover reprint of the original 1st ed. 1997)
Series: Handbook of Experimental Pharmacology, 130
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Pain is a symptom of many clinical disorders, afflicts a large
proportion of the population and is largely treated by
pharmacological means. However, the two main classes of drugs used
are the opioids and the non-steroidal anti inflammatory drugs,
drugs that have a long history. The last decade has seen remarkable
advances in our understanding of some of the pharmacological bases
of pain and analgesia and this book aims to reflect these rapid
changes in our understanding of pain mechanisms. One impetus to
these scientific advances has been dialogue and interactions
between scientists and clinicians; as a result we now has a number
of animal models of clinical pain states, to mimic certain aspects
of clinical pathophysiological pain states. Molecular aspects of
receptors and the synthesis of tools for probing receptor function
have also been rapid growth areas. A number of controlled clinical
studies using novel licensed drugs have also resulted from recent
research, offering hope to certain patients with severe intractable
pain. However, we desperately need the pharmaceutical industry to
develop new drugs based on these novel targets for analgesic
therapy. This book attempts to provide an overview of the important
areas of the pharmacology of pain. This book, although providing an
account of the pharmacology of pain transmission and its control
based on the underlying anatomical organization and physiological
responses, does not attempt to cover these latter two areas."
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