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Cerebral Blood Flow and Metabolism Measurement (Paperback, Softcover reprint of the original 1st ed. 1985)
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Cerebral Blood Flow and Metabolism Measurement (Paperback, Softcover reprint of the original 1st ed. 1985)
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At the present time several techniques are available for studying
quantitatively global and regional blood flow and metabolism of the
human brain. How ever, many scientists working in the clinical and
research field who would like to use these tools for their
investigations may be less familiar with the indi cations and
limitations of the individual methods. The rapid development of
both modern imaging techniques and new tracers may have led to some
con fusion in answering the question as to which method is
appropriate to solve the diagnostic problem of an individuum with
brain disease. Scepticism and ignorance as to the methods to be
used as tools in differential diagnosis of brain disorders may have
prevented their widespread introduction into clinical practice.
Thus, the significance of circulatory and metabolic parameters
involved in the majority of diseases of the central nervous system
may have been overlooked. The contributions compiled in this book
describe in detail the individual techniques, outline their
indications and limitations and deal in particular with newer
methods such as the atraumatic 133Xe technique, stable xenon
tomogra phy, three-dimensional techniques such as 133Xe single
photon emission tomog raphy and N-isopropyl-P23-iodoamphetamine.
Positron emission tomography studies provide information on
function and metabolism, particularly that of oxygen and glucose,
in regional brain areas of interest. Nuclear magnetic reso nance
may be a promising method for studying metabolic parameters;
however, accurate circulation measurements can not be performed at
present."
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