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Books > Medicine > General issues > Public health & preventive medicine > Epidemiology & medical statistics
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Clinical Trial Optimization Using R (Paperback)
Loot Price: R1,588
Discovery Miles 15 880
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Clinical Trial Optimization Using R (Paperback)
Series: Chapman & Hall/CRC Biostatistics Series
Expected to ship within 12 - 19 working days
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Clinical Trial Optimization Using R explores a unified and broadly
applicable framework for optimizing decision making and strategy
selection in clinical development, through a series of examples and
case studies. It provides the clinical researcher with a powerful
evaluation paradigm, as well as supportive R tools, to evaluate and
select among simultaneous competing designs or analysis options. It
is applicable broadly to statisticians and other quantitative
clinical trialists, who have an interest in optimizing clinical
trials, clinical trial programs, or associated analytics and
decision making. This book presents in depth the Clinical Scenario
Evaluation (CSE) framework, and discusses optimization strategies,
including the quantitative assessment of tradeoffs. A variety of
common development challenges are evaluated as case studies, and
used to show how this framework both simplifies and optimizes
strategy selection. Specific settings include optimizing adaptive
designs, multiplicity and subgroup analysis strategies, and overall
development decision-making criteria around Go/No-Go. After this
book, the reader will be equipped to extend the CSE framework to
their particular development challenges as well.
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