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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Membrane Organization and Dynamics (Hardcover, 1st ed. 2017)
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Membrane Organization and Dynamics (Hardcover, 1st ed. 2017)
Series: Springer Series in Biophysics, 20
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This volume brings together information on membrane organization
and dynamics from a variety of spectroscopic, microscopic and
simulation approaches, spanning a broad range of time scales. The
implication of such dynamic information on membrane function in
health and disease is a topic of contemporary interest. The
chapters cover various aspects of membrane lipid and protein
dynamics, explored using a battery of experimental and theoretical
approaches. The synthesis of information and knowledge gained by
utilizing multiple approaches will provide the reader with a
comprehensive understanding of the underlying membrane dynamics and
function, which will help to develop robust dynamic models for the
understanding of membrane function in healthy and diseased states.
In the last few years, crystal structures of an impressive number
of membrane proteins have been reported, thanks to tremendous
advances in membrane protein crystallization techniques. Some of
these recently solved structures belong to the G protein-coupled
receptor (GPCR) family, which are particularly difficult to
crystallize due to their intrinsic flexibility. Nonetheless, these
static structures do not provide the necessary information to
understand the function of membrane proteins in the complex
membrane milieu. This volume will address the dynamic nature of
membrane proteins within the membrane and will provide the reader
with an up-to date overview of the theory and practical approaches
that can be used. This volume will be invaluable to researchers
working in a wide range of scientific areas, from biochemistry and
molecular biology to biophysics and protein science. Students of
these fields will also find this volume very useful. This book will
also be of great use to those who are interested in the dynamic
nature of biological processes.
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