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Experimental Metastasis: Modeling and Analysis (Hardcover, 2013 ed.)
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Experimental Metastasis: Modeling and Analysis (Hardcover, 2013 ed.)
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Metastatic dissemination of cancer is a main cause of cancer
related deaths, therefore biological mechanisms implicated in
metastatic process presents an essential object of cancer research.
This research requires creation and utilization of adequate
laboratory models. The book describes main approaches to model
processes of metastatic cancer dissemination and metastases
development. The book is structured in according with various
metastatic pathways reflecting molecular specificity of metastatic
process as well as anatomical specificity of aria of dissemination.
Each chapter is introduced by short discussion of clinical aspects
of certain metastatic pathway. Especial attention is paid for
methods of visualization, quantification and analysis of the
modeled metastases. Additional chapter is devoted to methods of
mathematic modeling of tumor spread. The data presented in the book
may be helpful for cancer researchers and oncologists.
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