Cooperativity and Regulation in Biochemical Processes (Paperback, Softcover reprint of hardcover 1st ed. 2001)

This book evolved from a graduate course on applications of statistical thermody- namics to biochemical systems. Most of the published papers and books on this subject used in the course were written by experimentalists who adopted the phenomenological approach to describe and interpret their results. Two outstanding papers that impressed me deeply were the c1assical papers by Monod, Changeux, and Jacob (1963) and Monod, Wyman, and Changeux (1965), where the allosteric model for regulatory enzymes was introduced. Reading through them I feIt as if they were revealing one of the c1everest and most intricate tricks of nature to regulate biochemical processes. In 1985 I was glad to see T. L. HilI's volume entitled Cooperativity Theory in Biochemistry, Steady State and Equilibrium Systems. This was the fIrst book to systematically develop the molecular or statistical mechanical approach to binding systems. HilI demonstrated how and why the molecular approach is so advanta- geous relative to the prevalent phenomenological approach of that time. On page 58 he wrote the following (my italics): The naturalness of Gibbs' grand partition function for binding problems in biology is evidenced by the rediscovery of what is essentially the grand partition function for this particular type of problem by various physical biochentists, including E. Q. Adams, G.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Release date:	December 2010
First published:	2001
Authors:	Arieh Y. Ben-Naim
Dimensions:	229 x 152 x 19mm (L x W x T)
Format:	Paperback
Pages:	349
Edition:	Softcover reprint of hardcover 1st ed. 2001
ISBN-13:	978-1-4419-3336-2
Categories:	Books > Medicine > Nursing & ancillary services > Pharmacy / dispensing Books > Science & Mathematics > Physics > Applied physics & special topics > Biophysics Books > Science & Mathematics > Biology, life sciences > Biochemistry > General Promotions
LSN:	1-4419-3336-0
Barcode:	9781441933362

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