Volume 22, entitled Metal Ions in Bio-Imaging Techniques, of the
series Metal Ions in Life Sciences deals with metal ions as tools
in imaging. This dates back to the first half of the past century,
when barium sulfate was orally given to patients undergoing X-ray
examination. The use of contrast agents has since developed into a
large interdisciplinary field encompassing not only medicine, but
also chemistry, material sciences, physics, biology, engineering,
and computer sciences. MILS-22 provides deep and current insights
in 17 stimulating chapters on the new research frontiers of this
fast growing field on bio-imaging ... and beyond. For example,
adding bio-sensing yields theranostic agents, meaning diagnosis and
therapy linked in the same molecule; ions of Gd, Mn, Fe, Co, Ir,
99mTc, etc., are involved. Other important topics are, e.g., metal
complexes in paramagnetic Chemical Exchange Transfer (paraCEST),
radiometals for Positron Emission Tomography (PET) imaging, or
paramagnetic metal ion probes for 19F magnetic resonance imaging.
MILS-22 is written by 57 internationally recognized experts from 12
countries, that is, from the US via Europe to China. The impact of
this vibrant research area is manifested by more than 2300
references and nearly 120 figures, mostly in color, and several
informative tables. To conclude, Metal Ions in Bio-Imaging
Techniques is an essential resource for scientists working in the
wide range from material sciences, enzymology, analytic, organic,
and inorganic biochemistry all the way through to medicine
including the clinic ... not forgetting that also excellent
information for teaching is provided.
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