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The World of Nano-Biomechanics (Paperback, 2nd edition)
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The World of Nano-Biomechanics (Paperback, 2nd edition)
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The World of Nano-Biomechanics, Second Edition, focuses on the
remarkable progress in the application of force spectroscopy to
molecular and cellular biology that has occurred since the book's
first edition in 2008. The initial excitement of seeing and
touching a single molecule of protein/DNA is now culminating in the
development of various ways to manipulate molecules and cells
almost at our fingertips, enabling live cell operations. Topics
include the development of molecular biosensors, mechanical
diagnosis, cellular-level wound healing, and a look into the
advances that have been made in our understanding of the
significance of mechanical rigidity/flexibility of protein/DNA
structure for the manifestation of biological activities. The book
begins with a summary of the results of basic mechanics to help
readers who are unfamiliar with engineering mechanics. Then,
representative results obtained on biological macromolecules and
structures, such as proteins, DNA, RNA, polysaccharides, lipid
membranes, subcellular organelles, and live cells are discussed.
New to this second edition are recent developments in three
important applications, i.e., advanced AFM-data analysis,
high-resolution mechanical biosensing, and the use of cell
mechanics for medical diagnosis.
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