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Bioassay Techniques for Drug Development (Hardcover)
Loot Price: R5,042
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Bioassay Techniques for Drug Development (Hardcover)
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The goal of an activity-directed isolation process is to isolate
bioactive compounds which may provide structural leads of
therapeutic importance. Whereas the traditional process of drug
development is long and expensive, simple and rapid bioassays can
serve as the starting point for drug discovery. This book presents
a range of "bench top" bioassay techniques useful for natural
product and pharmaceutical chemists involved in drug discovery and
pharmacognosy. The contents detail a number of enzyme-based assays,
cell-based functional bioassays and receptor radioligand binding
assays along with detailed descriptions of each type. The majority
of these bioassays are presented in a step-by-step format, so they
could even be implemented by technical personnel with little
background in microbiology, biochemistry or pharmacology.
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