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Books > Science & Mathematics > Biology, life sciences > Microbiology (non-medical)
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Iron Acquisition by the Genus Mycobacterium - History, Mechanisms, Role of Siderocalin, Anti-Tuberculosis Drug Development (Paperback, 2013 ed.)
Loot Price: R1,481
Discovery Miles 14 810
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Iron Acquisition by the Genus Mycobacterium - History, Mechanisms, Role of Siderocalin, Anti-Tuberculosis Drug Development (Paperback, 2013 ed.)
Series: SpringerBriefs in Biometals
Expected to ship within 10 - 15 working days
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Iron Acquisition by the Genus Mycobacterium summarizes the early
evidence for the necessity of iron in mycobacteria and the
discovery of the mycobacterial siderophores mycobactin,
carboxymycobactin, and exochelin. The structural characterization
of the mycobacterial siderophores is described. The genes so far
identified as essential for iron acquisition and maintenance of an
infection by pathogenic mycobacteria are discussed. The potential
role of siderocalin in iron gathering by M. tuberculosis is
featured. Because new drugs for M. tuberculosis are needed, this
brief also emphasizes the design of antibiotics that interfere with
siderophore biosynthesis and the use of siderophore analogs and/or
conjugates.
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