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Growth Hormone II - Basic and Clinical Aspects (Paperback, Softcover reprint of the original 1st ed. 1994)
Loot Price: R2,819
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Growth Hormone II - Basic and Clinical Aspects (Paperback, Softcover reprint of the original 1st ed. 1994)
Series: Serono Symposia USA
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This book is a compendium of proceedings from the Symposium on
Growth Hormone II: Basic and Clinical Aspects. The intent of the
sym posium was to review current aspects of the rapidly expanding
science of growth hormone (GH) neuroendocrinology, especially those
develop ments that occurred since our last meeting in 1985. The
meeting was timely since there have been many new and exciting
developments in basic research on the GH axis, and several new
clinical applications for GH other than growth have been
identified. For example, significant strides have been made into
use of the bioengineered hormone as an anabolic in debilitated
states and as an immunorestorative agent. Both these areas have
received most attention as they relate to geriatric popu lations.
Furthermore, recent focus on a novel family of GH secretagogues
that complement the action of GHRH has shown that in animal models,
these compounds have the potential to restore GH secretion in
deficient or insufficient states, including growth retardation,
obesity, and aging. Accordingly, these xenobiotics may have
significant potential as drug products to stimulate physiological
GH secretion and, thus, resist or reverse some of the maladaptive
changes in form and function resulting from GH insufficiency. The
importance of these agents as drug candidates is underscored by the
diversity of molecules that have been studied by various
pharmaceutical companies and the recent discovery that non peptide
analogs with high oral bioavailability can be synthesized."
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