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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Henipavirus - Ecology, Molecular Virology, and Pathogenesis (Paperback, 2012 ed.)
Loot Price: R5,181
Discovery Miles 51 810
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Henipavirus - Ecology, Molecular Virology, and Pathogenesis (Paperback, 2012 ed.)
Series: Current Topics in Microbiology and Immunology, 359
Expected to ship within 10 - 15 working days
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Henipaviruses form a new genus of emerging paramyxoviruses that are
the deadliest human pathogens within the Paramyxoviridae family.
This volume deals with the many facets of henipavirus biology, and
covers our current understanding regarding the ecology, molecular
virology, and pathogenesis of henipavirus infections. It is an
international effort written by a multidisciplinary panel of
experts at the front lines of research into this lethal emerging
group of paramyxoviruses. The first section introduces the
epidemiology and ecology of Nipah and Hendra viruses in their
respective endemic areas, including a first-hand account of the
discovery of Nipah virus during its initial outbreak in Malaysia;
the next section documents the molecular virology of henipaviruses,
and the substantial advances made towards understanding the unique
features of henipavirus entry and tropism; and this is followed by
accounts of the clinical and pathologic features of henipavirus
infections in their human and naturally infected animal hosts. The
next sections on pathogenesis provide a comprehensive reference on
how henipaviruses counteract the innate immune system, and the
relevant pathogenic features in animal challenge models developed
to test potential therapeutic strategies. The final sections
describe our current and future capabilities for diagnosis and
control, including an account of potentially effective immunization
strategies that are currently being tested. This book will not only
serve as a useful reference for the henipavirus field; it will be
useful to basic and animal virologists, ecologists,
epidemiologists, physicians, and others interested in emerging
infectious viral diseases, as it showcases the multidisciplinary
efforts required to understand the genesis, spread and hopefully,
control, of a group of lethal emerging zoonotic pathogens.
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