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Metabolic Turnover in the Nervous System (Paperback, Softcover reprint of the original 1st ed. 1971)
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Metabolic Turnover in the Nervous System (Paperback, Softcover reprint of the original 1st ed. 1971)
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Volume V deals with the problems of turnover in the nervous system.
"Turnover" is defined in different ways, and the term is used in
different contexts. It is used rather broadly in the present
volume, and intentionally so. The turnover of macromolecules is
only one aspect; here "turnover" in dicates the simultaneous and
coordinated formation and breakdown of macromolecular species. The
complexities of cerebral protein turnover are shown in aseparate
chapter dealing with the synthesis ofproteins, in another on
breakdown, and in still another on the relationship ofthese two
(showing how the two halves of turnover are controlled). The fact
that most likely the two halves of protein turnover, synthesis and
breakdown, are separated spatially and the mechanisms involved are
different further emphasizes the complexity of macromolecular
turnover. "Turnover" is used in a different context when the
turnover of a cycle is discussed; but he re again a number of
complex metabolic reactions have to be interrelated and controlled;
some such cycles are discussed briefly in this volume, additional
cycles have been discussed with metabolism, and some cycles still
await elucidation or discovery.
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