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Protein Function Prediction for Omics Era (Paperback, 2011 ed.)
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Protein Function Prediction for Omics Era (Paperback, 2011 ed.)
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Gene function annotation has been a central question in molecular
biology. The importance of computational function prediction is
increasing because more and more large scale biological data,
including genome sequences, protein structures, protein-protein
interaction data, microarray expression data, and mass spectrometry
data, are awaiting biological interpretation. Traditionally when a
genome is sequenced, function annotation of genes is done by
homology search methods, such as BLAST or FASTA. However, since
these methods are developed before the genomics era, conventional
use of them is not necessarily most suitable for analyzing a large
scale data. Therefore we observe emerging development of
computational gene function prediction methods, which are targeted
to analyze large scale data, and also those which use such omics
data as additional source of function prediction. In this book, we
overview this emerging exciting field. The authors have been
selected from 1) those who develop novel purely computational
methods 2) those who develop function prediction methods which use
omics data 3) those who maintain and update data base of function
annotation of particular model organisms (E. coli), which are
frequently referred
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