Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity, Volume 47 (Paperback)

Sodium reabsorbing epithelia play a major role in whole-body sodium homeostasis. Some examples of sodium regulating tissues include kidney, colon, lung, and sweat ducts. Sodium transport across these membranes is a two-step process: entry through an amiloride-sensitive sodium channel and exit via the ouabain-sensitive sodium/potassium ATPase. The sodium entry channels are the rate-limiting determinant for transport and are regulated by several different hormones. The sodium channels also play a significant role in a number of disease states, like hypertension, edema, drug-induced hyperkalemia, and cystic fibrosis. Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity provides the first in-depth exchange of ideas concerning these sodium channels, their regulation and involvement in normal and pathophysiological situations.
Key Features
* Summarizes current state of amiloride-sensitive sodium channel field
* Analyzes structure-function of epithelial sodium channels
* Discusses immunolocalization of epithelial sodium channels
* Examines hormonal regulation of sodium channels
* Discusses sodium channels in lymphocytes, kidney, and lung
* Considers mechanosensitivity of sodium channels
* Provides ideas on sodium channels and disease

General

Imprint:	Academic Press Inc
Country of origin:	United States
Series:	Current Topics in Membranes
Release date:	October 1999
First published:	1999
Series editors:	Douglas M. Fambrough
Volume editors:	Dale J. Benos
Dimensions:	229 x 152 x 27mm (L x W x T)
Format:	Paperback
Pages:	384
ISBN-13:	978-0-12-089030-9
Categories:	Books > Science & Mathematics > Physics > Applied physics & special topics > Biophysics Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
LSN:	0-12-089030-5
Barcode:	9780120890309

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