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Molecular and Cellular Genetics, Volume 5 (Hardcover)
Loot Price: R2,443
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Molecular and Cellular Genetics, Volume 5 (Hardcover)
Series: Principles of Medical Biology
Expected to ship within 12 - 17 working days
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The tools of molecular biology have revolutionised our
understanding of gene structure and function and changed the
teaching of genetics in a fundamental way. The transition from
classical genetics to molecular genetics was initiated by two
discoveries. One was the discovery that DNA has a complementary
double helix structure and the other that a universal genetic code
does exist. Both led to the acceptance of the central dogma that
RNA molecules are made on DNA templates.
The last twenty years have seen remarkable growth in our knowledge
of molecular genetics, most of which is the outcome of recombinant
DNA technology. This technology which is not limited to cloning,
sequencing, and expression has created a biotechnology industry of
its own, the purpose of which is to develop new diagnostic and
therapeutic approaches in medicine. Both industries in
collaboration with the biomedical community are now engaged in
laying down the foundation of molecular medicine.
The present volume seeks to provide a coherent account of the new
science of molecular genetics. Its content however is by no means
exhaustive, partly because of the publication explosion but more
because of space restrictions. A rudimentary knowledge of genetics
on the reader's part is assumed. Quite understandably, considerable
emphasis is placed on major technical advances but not without
expounding numerous new ideas and phenomena including alternative
splicing, POR, DNA methylation, genomic imprinting, and so on.
General
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