GW bodies are novel cytoplasmic foci that were discovered and named
by Dr. Chan's group in 2002. These bodies are now known to be
active cytoplasmic foci involved with the new gene regulation
process mediated by microRNA that leads to translational repression
and mRNA degradation. The detailed biological functions of these
cytoplasmic structures are still being uncovered and the idea for
this book is to provide the history of the discovery and the major
work from different laboratories that has led to the
characterization and elucidation of the structure and function of
these new multiple subcellular structures.
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