Eicosanoid Protocols (Paperback, 1999 ed.)

Since the pioneering work of U. S. VonEuler, G. O. Burr, B. Samuelsson, and others in the field of eicosanoids, research in this area continues to grow rapidly. Novel eicosanoids are being discovered even as enzymes that ca- lyze the synthesis of well-established eicosanoids are being critically studied with respect to their regulation and function. The novice in this field will most likely encounter three areas of intense research activity: regulation of expression and function of enzymes, i.e., ph- pholipases, cyclooxygenases, and lipoxygenases involved in the syntheses of established eicosanoids, characterization and distribution in tissues of eicosanoid receptors, and discovery and biologic roles of novel eicosanoids. This book is a compilation of chapters addressing these three areas. Most chapters of Eicosanoid Protocols address the first area, giving p- ticular emphasis to the cyclooxygenases and their two isoforms. This was done intentionally, because the discovery of the constitutive and inducible isoforms of this enzyme have introduced new concepts in the pathobiology of inflammation and in the use of nonsteroidal anti-inflammatory drugs. Although receptors of most established eicosanoids have been characterized and cloned, only one chapter (on the thromboxane A receptor) was devoted to this area.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Molecular Biology, 120
Release date:	March 1999
First published:	1999
Editors:	Elias A Lianos
Dimensions:	229 x 152 x 17mm (L x W x T)
Format:	Paperback
Pages:	296
Edition:	1999 ed.
ISBN-13:	978-0-89603-667-3
Categories:	Books > Science & Mathematics > Biology, life sciences > Molecular biology Books > Science & Mathematics > Science: general issues > Scientific equipment & techniques, laboratory equipment > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > Enzymology Promotions
LSN:	0-89603-667-7
Barcode:	9780896036673

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