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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Prostaglandins in Cancer Research (Paperback, Softcover reprint of the original 1st ed. 1987)
Loot Price: R2,973
Discovery Miles 29 730
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Prostaglandins in Cancer Research (Paperback, Softcover reprint of the original 1st ed. 1987)
Series: Proceedings in Life Sciences
Expected to ship within 10 - 15 working days
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Arachidonic acid metabolites are known to playa regulatory role in
a number of biological systems, in which they function as
microenviron mental hormones and intracellular signal mediators.
One of the most exciting areas of research of these compounds is
the one that studies the relationship between prostaglandins and
tumor cell growth and function. In the last few years there has
been an extraordinary evolution of data on prostaglandins (and
related compounds) and cancer. This vol ume is based on papers
presented at the 1986 International Confer ence on Prostaglandins
and Cancer organized by the Italian National Research Council and
the II University of Rome, and held in Rome, Italy, in June, 1986.
This Conference brought together oncologists and specialists in the
areas of prostaglandin chemistry, biochemistry, pharmacology,
physiology, cellular and molecular biology to overview the actual
state of knowledge on the role of eicosanoids in cancer and to
focus on the key questions that need to be answered. The picture
that comes out of this book describes a very complicated network of
interactions between arachidonic acid metabolites and different as
pects of the complex phenomenon "cancer." Eicosanoids participate
in carcinogenesis initiation and promotion, and their relationship
with tumor promoters and growth factors is well established. During
cancer growth, different prostaglandins can have different roles in
the regulation of cell proliferation and differentiation and in
metastasis formation; meanwhile evidence is accumulating for a pos
sible use of some of these compounds as antineoplastic agents."
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