To celebrate the 40th anniversary of the discovery of Natural
Killer (NK) cells, this volume focuses on the recent advances in
our understanding of NK cell development and differentiation and
their acquisition of functional properties, as well as the latest
models for NK-cell analysis in mice and applications in clinical
medicine. NK cells have travelled a circuitous path from their
initial description as 'spontaneous killers' (for some simply an
experimental artifact) to being a bona fide subset of innate
lymphoid cells with a complementary mode of action in immune
defense and an important mediator of immune reactivity in health
and disease. Together, these reviews provide a timely and concise
picture of the evolution of NK cells as essential agents in
immunity and as potent weapons against disease. This book offers an
appealing and insightful resource for scientists and clinicians.
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