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Vaccines - New Generation Immunological Adjuvants (Paperback, Softcover reprint of the original 1st ed. 1995)
Loot Price: R2,908
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Vaccines - New Generation Immunological Adjuvants (Paperback, Softcover reprint of the original 1st ed. 1995)
Series: NATO Science Series A:, 282
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During the last decade or so vaccine development has been
facilitated by rapid advances in molecular and cell biology. These
have laid the foundations of a new generation of vaccines
exemplified by subunit vaccines produced through gene cloning and
by synthetic peptides mimicking small regions of proteins on the
outer coat of viruses. Such peptide~ are capable of eliciting
virus-neutralizing antibodies. Unfortunately, subunit and peptide
vaccines are only weakly or non immunogenic in the absence of
immunological adjuvants that are known to augment specific
cell-mediated immune responses to the antigens and to promote the
formation of protective antibodies. This book contains the
proceedings of the 4th NATO Advanced Studies Institute (ASI)
"Vaccines: New Generation Immunological Adjuvants" held at Cape
Sounion Beach, Greece, during 24 June -5 . July 1994 and deals in
depth with both theoretical and practical aspects of vaccinology.
These include the role of antigen presenting cells in the induction
of immune responses. immunopotentiation by a variety of new
generation immunological adjuvants and vaccine carriers. and recent
advances and perspectives in experimental vaccines as well as
vaccinatioll with nucleic acids. We express our appreciation to Dr.
K. Dalsgaard and Dr. J. L. Virelizier for their cooperatioll in
planning the ASI and to Mrs. Concha Pening for her excellent
production of the manuscripts. The ASI was held under the
sponsorship of NATO Scientific Affairs Division and generously
co-sponsored by SmithKline Beecham Pharmaceuticals (Philadelphia).
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