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Books > Professional & Technical > Biochemical engineering > Biotechnology
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Metabolic Engineering - Principles and Methodologies (Hardcover)
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Metabolic Engineering - Principles and Methodologies (Hardcover)
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Metabolic engineering is a new field with applications in the
production of chemicals, fuels, materials, pharmaceuticals, and
medicine at the genetic level. The field's novelty is in the
synthesis of molecular biology techniques and the tools of
mathematical analysis, which allow rational selection of targets
for genetic modification through measurements and control of
metabolic fluxes. The objective is to identify specific genetics or
environmental manipulations that result in improvements in yield
and productivities of biotechnological processes.
Key features of the book are pathway integration and the focus on
metabolic flux as a fundamental determinant of cell physiology. The
book keeps mathematical complexity to a minimum, and provides a
glossary of biological terms to facilitate use of the book by a
broader spectrum of readers. A web page exists to communicate
updates of the codes and homework problems.
Key Features
* Demonstrates metabolic engineering in action with numerous
examples of pathway modification
* Includes methods for identifying key enzymes in metabolic
networks
* Contains a comprehensive review of metabolic biochemistry
* Discusses metabolic regulation at the gene, enzyme, operon, and
cell levels
* Explains concepts of stoichiometry, kinetics, and thermodynamics
of metabolic pathways
* Minimizes mathematical complexity
* Links to a Web page to communicate updates of the software code
and homework problems
General
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