Structure and Function of GPCRs (Hardcover, 1st ed. 2019)

This book introduces readers to the latest advances in G protein-coupled receptor (GPCR) biology. It reviews our current understanding of the structural basis of ligand binding and allosteric mechanisms, following a decade of technological breakthroughs. Several examples of structure-based drug discovery are presented, together with the future challenges involved in designing better drugs that target GPCRs. In turn, the book illustrates the important concept of GPCR biased signaling in physiological contexts, and presents fluorescent- and light-based methodologies frequently used to measure GPCR signaling or to trace their dynamics in cells upon ligand activation. Taken together, the chapters provide an essential overview and toolkit for new scientific investigators who plan to develop GPCR projects. All chapters were written by experts in their respective fields, and share valuable insights and powerful methodologies for the GPCR field.

General

Imprint:	Springer Nature Switzerland AG
Country of origin:	Switzerland
Series:	Topics in Medicinal Chemistry, 30
Release date:	August 2019
First published:	2019
Editors:	Guillaume Lebon
Dimensions:	235 x 155mm (L x W)
Format:	Hardcover
Pages:	289
Edition:	1st ed. 2019
ISBN-13:	978-3-03-024589-4
Categories:	Books > Science & Mathematics > Biology, life sciences > Biochemistry > General Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology Books > Science & Mathematics > Chemistry > Analytical chemistry > Qualitative analytical chemistry > Chemical spectroscopy, spectrochemistry > General
LSN:	3-03-024589-6
Barcode:	9783030245894

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