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Books > Science & Mathematics > Physics > Applied physics & special topics > Biophysics
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Methods in Pharmacology - Molecular and Cellular Biology of Pharmacological Targets (Paperback, Softcover reprint of hardcover 1st ed. 1993)
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Methods in Pharmacology - Molecular and Cellular Biology of Pharmacological Targets (Paperback, Softcover reprint of hardcover 1st ed. 1993)
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In this volume of Methods in Pharmacology we have brought together
experts in the field of ion channels to provide the reader with an
in-depth view of current biochemical and electrophysiological
methods. The focus is on cation-selective ion channels (voltage
controlled Of ligand controlled) that are of special
pharmacological interest. The con- tents are divided into three
sections that exemplify {I) molecular and biochemical
characterization of ion channels, (II) functional analysis of ion
channels (after recon- stitution or expression, or in cells), and
(III) specific methods and tools. The editors thank the
contributors for their cooperation in assembling this volume. We
are convinced that the reader will enjoy the chapters, written by
leading scientists in their respective disciplines, as much as we
did. Hartmut Glossmann Jarg Striessnig Innsbruck, Austria vii
Contents I MOLECULAR AND BIOCHEMICAL CHARACTERIZA nON OF ION
CHANNELS 1 Purification and Pharmacological Analysis of the
Omega-Conotoxin 3 GVIA Receptor from Rat Brain Maureen W McEnery 2
Molecular Characterization of the Charybdotoxin-Sensitive, 41
High-Conductance, Calcium-Activated Potassium Channel Margarita
Garda-Calvo, Gregory J. Kaczorowski, and Maria L. Garda 3
Characterization of the Sulfonylurea-Sensitive ATP-Modulated 61
Potassium Channel Henri Bernardi and Michel Lazdunski II FUNCTIONAL
ANALYSIS OF ION CHANNELS 4 Xenopus Oocytes as an Expression System
for Ion Channels 79 Alan L. Goldin ix x Contents 5 Reconstitution
of Muscle Calcium Channel Function in Bilayer 99 Membranes: From
the First Steps to Results Dieter J. Pelzer, Terence F.
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