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Prion Diseases (Hardcover, 1996 ed.)
Loot Price: R4,335
Discovery Miles 43 350
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Prion Diseases (Hardcover, 1996 ed.)
Series: Methods in Molecular Medicine, 3
Expected to ship within 12 - 17 working days
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Harry Baker and Rosalind Ridley have done an admirable job in assem
bling this collection of articles that describe the methodology
frequently used to study a group of CNS illnesses often referred to
as the "prion diseases." Research on prions and the disorders that
they cause has progressed relatively rapidly over the last decade
since the discovery of the prion protein (PrP) that allowed the
application of modem molecular biological and genetic tools. The
power of these techniques is awesome and their use in deciphering
the once mysterious prion diseases has brought a wealth of new
information. Although prions are unprecedented pathogens, appearing
to consist only of PrPSc molecules, the diseases that they cause
are no less remarkable. The prion diseases in animals include
scrapie of sheep and goats as well as "mad cow" disease or bovine
spongiform encephalopathy (BSE). In the United King dom, the
epidemic of BSE has heightened public awareness of this previously
obscure group of diseases such that any work in the field is likely
to stir up interest in the media and become a subject of public
debate. It has been diffi cult for British investigators to work on
prion diseases without being involved in these controversies. As
such, several chapters have been included that deal with political
and social issues surrounding prion diseases. The human prion
diseases present an equally fascinating saga in which these CNS
degenerations present as genetic, sporadic, and infectious
illnesses."
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