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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Molecular and Cellular Mechanisms of Cardiovascular Regulation (Hardcover)
Loot Price: R1,603
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Molecular and Cellular Mechanisms of Cardiovascular Regulation (Hardcover)
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This volume contains selected papers presented at the Sendai
International Sympo sium on Molecular and Cellular Mechanisms of
Cardiovascular Regulation held from May 10-12, 1995, to honor the
contributions ofProfessorNorio Taira, Chairman of the Department of
Pharmacology (1972-1995), Tohoku University School of Medicine,
Sendai, Japan. The Department of Pharmacology at Sendai has a long
tradition of significant contribution to the development of drug
therapy for cardiovascular diseases. The late Professor Koroku
Hashimoto, the predecessor of Professor Norio Taira, first
suggested the mode of action of calcium antagonists and their
potential usefulness in therapy of ischemic heart disease and
hypertension at an early stage of their development. The need for
greater understanding of the pathophysiology of cardiovascular dis
eases is more critical now than ever before because modern advances
in basic and clinical sciences have prolonged the average life
expectancy. Using a wide range of molecular and
electrophysiological techniques, major advances are occurring
frequently in the field of cardiovascular physiology and
pharmacology. Such multifaceted approaches are preferred because
human cardiovascular diseases are complex, requiring multiple
interventions and an in-depth understanding of molecular mechanisms
underlying the disease. The first section of this book focuses on
molecular mechanisms of ion channel regulation. Eight of ten
chapters in this section are devoted to the recent advances in
molecular characterization and regulation of various types of
potassium channels in cardiac, vascular, and neuronal tissues. A
discussion of the structure and function of sodium and calcium
channels is also included.
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