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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Vascular Ion Channels in Physiology and Disease (Hardcover, 1st ed. 2016)
Loot Price: R6,846
Discovery Miles 68 460
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Vascular Ion Channels in Physiology and Disease (Hardcover, 1st ed. 2016)
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Ion channels are the major class of membrane proteins responsible
for rapid and regulated transport of ions across biological
membranes and for the generation and propagation of electrical
signals in the brain, heart, and skeletal and vascular tissues. Ion
channels are also known to play critical roles in regulation of
cell proliferation, insulin secretion and intracellular signaling
in a variety of cell types. This book focuses on the roles of ion
channels in vascular tissues under normal and pathological
conditions. Vascular abnormalities are known to underlie a plethora
of severe pathological conditions, such as atherosclerosis,
systemic and pulmonary hypertension, coronary or cerebral
vasospasm, and diabetes. In addition, misregulated angiogenesis is
one of the major contributors to the development of tumors.
Therefore, it is clearly imperative to obtain a better
understanding of the molecular mechanisms that contribute to
vascular disorders. This book will be the first comprehensive
assembly of assays to present the studies that have been done
during the last decade to elucidate the roles of ion channels in
different vascular diseases.
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