Biomedical Applications of Acridines - Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases (Hardcover, 1st ed. 2017)

This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine. Using modern data-mining software, it presents structures of acridines with nucleic acids and proteins and compares them with the native structures. Furthermore, the book presents modern methods of acridine synthesis, comparing them with the most useful conventional methods. Acridines interact with both nucleic acids and proteins, and due to their direct interactions with various enzymes, they can be suitable for the treatment of neurodegenerative diseases, inflammation, immunological disorders, and protozoal diseases. The characteristic spectral properties of acridines can be employed in labeling proteins, nucleic acids, lipids, and even cells and their compartments. Moreover, they can be applied in photodynamic therapy.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Series:	Progress in Drug Research, 72
Release date:	August 2017
First published:	2017
Authors:	Jan Jezek • Jan Hlavacek • Jaroslav Sebestik
Dimensions:	235 x 155mm (L x W)
Format:	Hardcover
Pages:	237
Edition:	1st ed. 2017
ISBN-13:	978-3-319-63952-9
Categories:	Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology Books > Medicine > Other branches of medicine > Pharmacology > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins Promotions
LSN:	3-319-63952-8
Barcode:	9783319639529

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