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Books > Medicine > Clinical & internal medicine > Geriatric medicine
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Retinal Degenerative Diseases - Mechanisms and Experimental Therapy (Paperback, Softcover reprint of the original 1st ed. 2014)
Loot Price: R8,686
Discovery Miles 86 860
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Retinal Degenerative Diseases - Mechanisms and Experimental Therapy (Paperback, Softcover reprint of the original 1st ed. 2014)
Expected to ship within 10 - 15 working days
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This book will contain the proceedings of the XV International
Symposium on Retinal Degeneration (RD2012). A majority of those who
will speak and present posters at the meeting will contribute to
this volume. The blinding diseases of inherited retinal
degenerations have no treatments, and age-related macular
degeneration has no cures, despite the fact that it is an epidemic
among the elderly, with 1 in 3-4 affected by the age of 70. The RD
Symposium will focus on the exciting new developments aimed at
understanding these diseases and providing therapies for them.
Since most major scientists in the field of retinal degenerations
attend the biennial RD Symposia, they are known by most as the
"best" and "most important" meetings in the field. The volume will
present representative state-of-the-art research in almost all
areas of retinal degenerations, ranging from cytopathologic,
physiologic, diagnostic and clinical aspects; animal models;
mechanisms of cell death; candidate genes, cloning, mapping and
other aspects of molecular genetics; and developing potential
therapeutic measures such as gene therapy and neuroprotective
agents for potential pharmaceutical therapy. While advances in
these areas of retinal degenerations will be described, there will
be many new topics that either were in their infancy or did not
exist at the time of the last RD Symposium, RD2010. These include
the role of inflammation and immunity, as well as other basic
mechanisms, in age-related macular degeneration, several new
aspects of gene therapy, and revolutionary new imaging and
functional testing that will have a huge impact on the diagnosis
and following the course of retinal degenerations, as well as to
provide new quantitative endpoints for clinical trials. The retina
is an approachable part of the central nervous system (CNS), and
there is a major interest in neuroprotective and gene therapy for
CNS diseases and neurodegenerations, in general. It should be noted
that with successful and exciting initial clinical trials in
neuroprotective and gene therapy, including the restoration of
sight in blind children, the retinal degeneration therapies are
leading the way towards new therapeutic measures for
neurodegenerations of the CNS. Many of the successes recently
reported in these areas of retinal degeneration sprang from
collaborations established at previous RD Symposia, and many of
those will be reported at the RD2010 meeting and included in the
proposed volume. We anticipate the excitement of those working in
the field and those afflicted with retinal degenerations will be
reflected in the volume.
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