The means by which non-enveloped viruses penetrate cellular
membranes during cell entry remain poorly defined. Recent findings
indicate several members of this group share a common mechanism of
membrane penetration in which the virus particle undergoes
programmed conformational changes, leading to capsid disassembly
and release of small membrane-interacting peptides. A complete
understanding of host cell entry by this minimal system will help
elucidate the mechanisms of non-enveloped virus membrane
penetration in general
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