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Immunobiology of Parasites and Parasitic Infections (Paperback, Softcover reprint of the original 1st ed. 1984)
Loot Price: R3,069
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Immunobiology of Parasites and Parasitic Infections (Paperback, Softcover reprint of the original 1st ed. 1984)
Series: Contemporary topics in immunobiology, 12
Expected to ship within 10 - 15 working days
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The phenomena involved in infections of man and domestic animals
with metazoan or protozoan parasites present formidable practical
problems as well as a theoretical challenge to immunologists,
molecular biologists, and evolu tionary biologists. With respect to
the public health and economic problems, malaria, for example,
remains a major health problem with approximately 200 million
people being infected yearly and, on the basis of World Health
Organiza tion estimates, more than 1 million children die each year
of malaria infections (Chapter 4). This volume addresses
state-of-the-art immunologic approaches to the development of
vaccines for parasitic diseases (Chapter 9) and analyses of studies
bearing on the antigenic characterization of protozoan and metazoan
parasites (Chapters 4, 5, and 7), on investigations of the role of
precise mecha nisms underlying natural resistance or non
permissiveness of the host to parasitic infections (Chapters 1, 2,
and 12), on induced mechanisms including the genera tion of
parasite-specific T-cell lines and clones (Chapter 6), and on the
generation of monoclonal antibodies (Chapters 4 and 5) to parasite
antigens of distinct de velopmental stages. Great progress has been
made in characterizing parasite antigens capable of inducing a
protective response in the vaccinated host; further progress in
this area strongly depends on biochemistry and molecular biology
with the long-term goal of synthesizing such antigens chemically or
producing them by means of recombinant DNA technology (Chapter 4).
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