Immunology has made significant progress in the past decade,
driven forward by rapidly advancing technology and a renewed
interest in the vast realm of innate immunity. The receptors that
mediate these functions are at the front lines of both protective
and regulative roles of the immune system. In "Immune Receptors:
Methods and Protocols," expert researchers present a variety of
experimental approaches to the characterization of immune receptors
and the cell biology that mediates their functions. These include
imaging techniques that aim to understand receptor localization and
trafficking, techniques to measure receptor-ligand interactions,
strategies to identify novel ligands and methods to analyze
downstream receptor signaling, as well as strategies for genomic
and proteomic characterization of receptor repertoires. Written in
the highly successful "Methods in Molecular Biology " series
format, chapters include introductions to their respective
subjects, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols, and tips
on troubleshooting and avoiding known pitfalls.
Authoritative and practical, "Immune Receptors: Methods and
Protocols" offers technical descriptions and protocols that will be
useful both to investigators who are interested in carrying out
these procedures and to those who seek a deeper understanding of
the bench science that lies behind the immunology literature."
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