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Books > Medicine > Clinical & internal medicine > Haematology
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Ectopeptidases - CD13/Aminopeptidase N and CD26/Dipeptidylpeptidase IV in Medicine and Biology (Paperback, Softcover reprint of the original 1st ed. 2002)
Loot Price: R2,662
Discovery Miles 26 620
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Ectopeptidases - CD13/Aminopeptidase N and CD26/Dipeptidylpeptidase IV in Medicine and Biology (Paperback, Softcover reprint of the original 1st ed. 2002)
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The idea to compile recent results on the ectoenzymes
aminopeptidase N/CD13 and dipeptidylpeptidase IV/CD26 arose from
the great interest given by readers world-wide to the two
proceedings volumes edited by us in 1997 and 2000 (Ansorge and
Langner, 1997; Langner and Ansorge, 2000). These volumes contained
the presentations at two symposia held in Magdeburg (Germany) in
1996 and 1999 under the title "Cellular peptidases in immune
functions and diseases", which was also the name of the
Sonderforschungsbereich in Magdeburg, sponsored by the Deutsche
Forschungsgemeinschaft between 1995 and 2001. Our groups in
Magdeburg and Halle during the last two decades have provided
results on these two enzymes in cells of the hematopoietic system
that justify a review in an edited monograph like the present one
(see the reviews by Kahne et at. , 1999; Lendeckel et at. ,1999;
Riemann et at. , 1999). There are, however, many other groups in
Europe, US and Japan which made important contributions to this
field and particularly in topics improving the understanding of
physiological and pathophysiological roles ofAPN/CD13 and
DPIV/CD26. Therefore we decided to invite some of them to
contribute reviews of their results to this book. Having worked for
about 40 years in the field of proteolysis, for both of us to see
the development of activities and knowledge from protein chemistry
and enzymology to physiology and pathophysiology and even to
therapy is very stimulating and fascinating. Of course, this
development also reflects the dramatic improvement and refinement
of methods.
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