Of the 121,000 people on donor lists in the U.S., over 100,000 need
kidney transplants and thousands die each year while waiting.
Bioprinting aspires to build healthy kidney tissue from a patient's
own cells and transplant this to boost failing kidneys without fear
of rejection... As the 21st century dawned, a handful of inspired
scientists tried to use 3D printing to create living human tissue.
Their vision was to restore the health of people with intractable
injuries, such as worn out cartilage, severed nerves, ailing
kidneys, failing hearts-the gamut of human frailties. Their modest
success energized others to join the quest. Now, after two decades
of ingenious effort and hard work, they have carved out a vibrant
new discipline: bioprinting. In Bioprinting: To Make Ourselves
Anew, physicist Kenneth Douglas casts an eye over the achievements
and future of bioprinting. He explains the science with rigor but
with a minimum of technical baggage. This is the first book on the
subject written expressly for the lay audience: accessible and even
entertaining. Douglas interviewed two dozen bioprinting researchers
from around the world, and he enriches the narrative by sharing
stories from the scientists behind the science. These contemporary
vignettes are complemented by historical accounts of the women and
men whose prescient contributions were foundational to the
development of bioprinting. The book describes the challenges and
accomplishments in the bioprinting of blood vessels, cartilage,
skin, bone, skeletal muscle, neuromuscular junctions, liver, heart,
lung, kidney, and so-called organs-on-a-chip, as well as the
challenges of providing a blood supply and nerves to bioprinted
tissues. This is a compelling tale of a work in progress: to
imitate nature and help heal people with debilitating afflictions.
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