Specificity, Function, and Development of NK Cells - NK Cells: The Effector Arm of Innate Immunity (Paperback, Softcover reprint of the original 1st ed. 1998)

Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors.

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	Current Topics in Microbiology and Immunology, 230
Release date:	March 2012
First published:	1998
Editors:	Klas Karre • Marco Colonna
Dimensions:	235 x 155 x 14mm (L x W x T)
Format:	Paperback
Pages:	248
Edition:	Softcover reprint of the original 1st ed. 1998
ISBN-13:	978-3-642-46861-2
Categories:	Books > Medicine > Clinical & internal medicine > Haematology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN:	3-642-46861-6
Barcode:	9783642468612

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