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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Experimental Models of Chronic Inflammatory Diseases (Paperback, Softcover reprint of the original 1st ed. 1977)
Loot Price: R3,096
Discovery Miles 30 960
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Experimental Models of Chronic Inflammatory Diseases (Paperback, Softcover reprint of the original 1st ed. 1977)
Series: Bayer-Symposium, 6
Expected to ship within 10 - 15 working days
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With the introduction of antibiotics acute inflammatory disease has
ceased to be the dominant problem in general medical practice and
its place is now increasingly occupied by chronic inflamma tory
disease of which the rheumatic diseases constitute the most
important group. lwo aspects of these diseases need to be consid
ered, their aetiology and their pathogenesis. In some respects the
latter is more important since even when the aetiology is known, as
for example the haemolytic streptococcus in rheumatic fever, the
mechanism by which the infecting agent accomplishes the development
of the lesions that characterise the disease are still largely
unknown. Still more so is this the case in rheuma toid arthritis
and other chronic inflammations where the aetio logical agents are
unknown. In an attempt to clarify the pathogenic mechanisms
involved, sev eral attempts have been made to induce comparable
lesions in ex perimental animals, partly to test underlying
hypotheses, and partly to provide test situations for the trial of
new therapeu tic agents. In view of the deficiencies in the current
drug treat ment of chronic inflammatory disease there are many who
feel that this is largely due to the inadequacy of the models avail
able for test purposes."
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