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Translational Pain Research - From Mouse to Man (Paperback)
Loot Price: R2,221
Discovery Miles 22 210
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Translational Pain Research - From Mouse to Man (Paperback)
Series: Frontiers in Neuroscience
Expected to ship within 12 - 17 working days
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One of the Most Rapidly Advancing Fields in Modern Neuroscience The
success of molecular biology and the new tools derived from
molecular genetics have revolutionized pain research and its
translation to therapeutic effectiveness. Bringing together recent
advances in modern neuroscience regarding genetic studies in mice
and humans and the practicality of clinical trials, Translational
Pain Research: From Mouse to Man effectively bridges the gap
between basic research and patient care by humanely examining
rodent models for pain associated with bone cancer, osteoarthritis,
fibromyalgia, and cardiac episodes. Distinguished Team of
International Contributors In addition to addressing the
groundbreaking technical advances in tract tracing,
endocannabinoids, cannabis, gene therapy, siRNA gene studies, and
the role of glia, cytokines, P2X receptors and ATP, this book also
presents cutting-edge information on: Nociceptor sensitization
Muscle nociceptors and metabolite detection Visceral afferents in
disease Innovative rodent model for bone cancer pain Highly
specific receptor cloning Modular molecular mechanisms relevant to
painful neuropathies This sharply focused work also discusses
unexpected discoveries derived from brain-imaging studies related
to thalamic pain. Translational Pain Research covers the progress
made toward bringing laboratory science (much of it at the
molecular level) to our understanding of pain phenomena in humans,
with the ultimate goal of reducing the suffering that often
accompanies pain and its indirect consequences.
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