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Symbiosis: Cellular, Molecular, Medical and Evolutionary Aspects (Paperback, 1st ed. 2020)
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Symbiosis: Cellular, Molecular, Medical and Evolutionary Aspects (Paperback, 1st ed. 2020)
Series: Results and Problems in Cell Differentiation, 69
Expected to ship within 10 - 15 working days
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This volume presents a comprehensive overview of the latest
developments in symbiosis research. It covers molecular,
organellar, cellular, immunologic, genetic and evolutionary aspects
of symbiotic interactions in humans and other model systems. The
book also highlights new approaches to interdisciplinary research
and therapeutic applications. Symbiosis refers to any mutually
beneficial interaction between different organisms. The symbiotic
origin of cellular organelles and the exchange of genetic material
between hosts and their bacterial and viral symbionts have helped
shaped the current diversity of life. Recently, symbiosis has
gained a new level of recognition, due to the realization that all
organisms function as a holobiome and that any kind of interference
with the hosts influences their symbionts and vice versa, and can
have profound consequences for the survival of both. For example,
in humans, the microbiome, i.e., the entirety of all the
microorganisms living in association with the intestines, oral
cavity, urogenital system and skin, is partially inherited during
pregnancy and influences the maturation and functioning of the
human immune system, protects against pathogens and regulates
metabolism. Symbionts also regulate cancer development, wound
healing, tissue regeneration and stem cell function. The medical
applications of this new realization are vast and largely
uncharted. The composition and robustness of human symbionts could
make them a valuable diagnostic tool for predicting impending
diseases, and the manipulation of symbionts could yield new
strategies for the treatment of incurable diseases.
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